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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2015). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Sci. Pharm. 2013, 81(3), 651-662; (registering DOI)

Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug

Chemical Research and Development Department, Aurobindo Pharma Ltd, Survey No: 71&72, Indrakaran (V), Sangareddy (M), Medak Dist., Hyderabad – 502 329, Andhra Pradesh, India
Department of Engineering Chemistry, A. U. College of Engineering (A), Andhra University, Visakhapatnam – 530 003, Andhra Pradesh, India
Author to whom correspondence should be addressed.
Received: 20 December 2012 / Accepted: 18 February 2013 / Published: 18 February 2013
PDF [145 KB, uploaded 28 September 2016]


Gatifloxacin is an antibacterial agent belonging to the fourth-generation fluoroquinolone family. Four piperazine-linked fluoroquinolone dimers of Gatifloxacin were observed during the laboratory process for Gatifloxacin and they were identified. The present work describes the origin, synthesis, characterization, and control of these dimers along with the synthesis of Despropylene Gatifloxacin (metabolite).
Keywords: Gatifloxacin; Piperazine dimers; Synthesis; Characterization Gatifloxacin; Piperazine dimers; Synthesis; Characterization
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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GARAGA, S.; REDDY, A.V.R.; PRABAHAR, K.J.; KORUPOLU, R.B.; SANASI, P.D. Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug. Sci. Pharm. 2013, 81, 651-662.

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