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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
Open AccessArticle

Synthesis and Antimicrobial Activity of 3-(1,3,4-Oxadiazol-2-yl)quinazolin-4(3H)-ones

Department of Chemistry, Veer Narmad South Gujarat University, Surat 395007, Gujarat, India
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Author to whom correspondence should be addressed.
Sci. Pharm. 2010, 78(2), 171-194; https://doi.org/10.3797/scipharm.0912-16
Received: 17 December 2009 / Accepted: 26 April 2010 / Published: 26 April 2010
In attempt to find new pharmacologically active molecules, we report here the synthesis and in vitro antimicrobial activity of various 3-(1,3,4-oxadiazol-2-yl)- quinazolin-4(3H)-ones. The antimicrobial activity of title compounds were examined against two gram positive bacteria (S. aureus, S. pyogenes), two gram negative bacteria (E. coli, P. aeruginosa) and three fungi (C. albicans, A. niger, A. clavatus) using the broth microdilution method. Some derivatives bearing a bromo or iodo group exhibited very good antimicrobial activity.
Keywords: Antimicrobial activity; 1,3,4-Oxadiazole; Quinazolin-4(3H)-one Antimicrobial activity; 1,3,4-Oxadiazole; Quinazolin-4(3H)-one
MDPI and ACS Style

PATEL, N.B.; PATEL, J.C. Synthesis and Antimicrobial Activity of 3-(1,3,4-Oxadiazol-2-yl)quinazolin-4(3H)-ones. Sci. Pharm. 2010, 78, 171-194.

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