Indirubine-3-Monoxime Inhibits PDGF-Mediated Vascular Smooth Muscle Cell Migration

SROKA, I.; HEISS, E. H.; CZALOUN, C.; DIRSCH, V. M.

doi:10.3797/scipharm.oephg.21.PO-45

Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).

Abstract

16 April 2009

1 Page

Indirubine-3-Monoxime Inhibits PDGF-Mediated Vascular Smooth Muscle Cell Migration

and

Department of Pharmacognosy, University of Vienna, Althanstr. 14, 1090, Vienna, Austria

Author to whom correspondence should be addressed.

Sci. Pharm.2009, 77(7), 244;https://doi.org/10.3797/scipharm.oephg.21.PO-45

Version Notes

Order Reprints

Abstract

During the pathology of atherosclerosis and restenosis, hyperproliferation and migration of vascular smooth muscle cells (VSMC) contribute to lumen loss of the vessel and neointima formation [1]. Drugs interfering with both, proliferation and migration of VSMC are therefore promising candidates for the treatment of vasculoproliferative diseases.

Article Metrics

Citations

Article Access Statistics

Journal Statistics

Multiple requests from the same IP address are counted as one view.

Distinct Anti-Migratory Effects of Resveratrol on EGF- versus PDGF-Stimulated Vascular Smooth Muscle Cells

Growth Factor-Induced Vascular Smooth Muscle Cell Proliferation is Inhibited by Tylophorine