Theoretical and Practical Considerations of the Newer Methods of the European Pharmacopeia for the Assay of Halide Salts of Organic Bases

Ragnar, Bye

doi:10.3797/scipharm.aut-02-15

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Article

1 May 2002

5 Pages

Theoretical and Practical Considerations of the Newer Methods of the European Pharmacopeia for the Assay of Halide Salts of Organic Bases

Ragnar Bye, University of Oslo, Department of Pharmacy, P.O. Box 1068, N-0316 Oslo, Norway

Sci. Pharm.2002, 70(2), 129-133;https://doi.org/10.3797/scipharm.aut-02-15

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A certain type of titration methods have appeared with an increasing frequency during the last years, this being evident surveying the latest editions of the European Pharmacopeia (1997-2001) [1-3], where there are now more than fifty monographs on the assay of halide salt of organic bases by potentiometric titration of the sample dissolved in ethanol or in an ethanolwater mixture with sodium hydroxide after addition of a defined volume of diluted hydrochloric acid [...]

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