Scientia Pharmaceutica, Volume 70, Issue 2

A survey of morphological and phytochemical data characteristic for several taxa of the Achillea millefoliurn group (A. aspleniifolia VENT., A. roseoalba EHREND., A. collina J. BECKER ex REICHENB., A. ceretanica SENNEN, A. setacea W. ET K., A. praten...

Matrix tablets of ketorolac trometharnine (KT) were prepared by direct compression technique and Carbopol 934, 940 and 1342 have been used as polymers in different concentrations (5-15 % ). For the quality control of tablets; physical tests as crushi...

The spiropiperidine derivatives have considerable importance in pharmaceutical chemistry due to their effects on different biological systems [...]

Danazol, a weekly androgenic, heterocyclic compound with anabolic properties, is used primarily in the treatment of endometriosis and other gynecological complaints. Effects of co-administration of enalapril, an angiotensin converting enzyme inhibito...

Tris(dimethy1amino)phosphine 1 reacted with phenylarylidene barbituric acids 4 to yield the triaminophosphonium dipolar ion adduct 7. 2-Arylidene-1,3- cyclohexanedione 5 and 2-Arylidene-5,5-dimethylcyclohaxane1-,3 -diones 6 reacted with phosphine 1 t...

We have evaluated vigabatrin (γ-vinyl γ-aminobutyric acid), an irreversible inhibitor of γ-aminobutyric acid (GABA)-transaminase responsible for GABA degradation, for its effects on food consumption, body weight changes, fluid intake, changes in hema...

A certain type of titration methods have appeared with an increasing frequency during the last years, this being evident surveying the latest editions of the European Pharmacopeia (1997-2001) [1-3], where there are now more than fifty monographs on t...

The synthesis of a novel quinazolinone was accomplished by the reaction of quinazolin- 2,4-(1H,3H)-dione with trifluoromethanesulfonic anhydride in triethylamine. The antimicrobial activity was determined against eight microorganisms. The organisms w...

The title compound 2 - prepared by Komblum reaction - reacted with Hg(II)-edta in a two electron withdrawal to a bicyclic compound 6, which showed in solution an equilibrium of two species probably of diastereomers, which was deduced from NMR-measure...