June 2001 - 12 articles
The cationic thiomer chitosan-thioglycolic acid (TGA) shows excellent mucoadhesive features. In order to deepen the knowledge concerning this new excipient the optimization of its synthesis and a detailed characterization of its properties was the ob...
Substituted phenylaminocarbonylaziridines are reacted with N-nitro-ethylcarbamate and then with ammonia to give N-aryl-N′-nitroaminoethyl-ureas 5-11 after acidification. 5 and 6 have a sweet taste, 7 is bitter.
Compacts prepared from binary combinations of Carbopol® 934 P (CP), Polycarbophil (Noveon® AA1, PC) and Hydroxy propyl cellulose (Klucel®, HPC) and coated on all but one flat surface with Poly Methyl Methacrylate - PMMA (chloroformic solution) were e...
Three simple, accurate and sensitive spectrophotometric methods (A, B and C) for the determination of cefuroxime and ceftazidime in bulk samples and in dosage forms are described. They are based on the reaction with nitrous acid forming a nitroso der...
A simple spectrophotometric methods has been developed for the determination of nortriptyline hydrochloride in pure and in pharmaceutical formulations based on the formation of ion-pair complexes with sudun II (SII), sudan (IV) (SIV) and sudan black...
The ring opening of isochromadiones by prop-2-ynylamine was accomplished in non-polar solvents to form N-prop-2-ynylbenzamide-2-acetic acid 3 N-prop-2-ynylhomophthalimide 4. Compound 3 was found out to be an intermediate product in the formation of 4...
It is quite well known that β-blockers influence the stability of cell membranes, but the effect of metoprolol on the composition of cell membrane lipids is not established. On the other hand, synchronous culture of Chlorella vulgaris cells, which co...
A spectrophotometric method for the selective determination of paracetamol based on its reaction with pyrochatechol violet under basic conditions to form an ion-pair complex is described. The absorption maximum of the coloured ion-pair formed is obse...
A simple and accurate method is described for the quantitative determination of flufenamic acid, mefenamic acid, tranexamic acid, furosemide, diclofenac sodium and thiaprofenic acid by precipitation reactions with nickel(II) followed by direct determ...
We have evaluated vigabatrin (γ-vinyi-γ-aminobutyric acid), an irreversible inhibitor of γ-aminobutyric acid (GABA)-transarninase responsible for GABA degradation, for its effects on nociceptive response, changes in spontaneous locomotor activity and...
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