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Sci. Pharm.
Volume 69
Issue 2
10.3797/scipharm.aut-01-20
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Article

Utility of Nickel for Atomic Absorption Spectrophotometric Determination of Selected Acidic Drugs

by
Hesham Salem
1,*,
Khadiga Kelani
2 and
Abdalla Shalaby
3
1
Analytical Chemistry Department, Faculty of Pharmacy, Minia University, EGYPT
2
Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, EGYPT
3
Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, EGYPT
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2001, 69(2), 189-201; https://doi.org/10.3797/scipharm.aut-01-20
Submission received: 21 February 2001 / Accepted: 5 April 2001 / Published: 30 June 2001
Versions Notes

Abstract

A simple and accurate method is described for the quantitative determination of flufenamic acid, mefenamic acid, tranexamic acid, furosemide, diclofenac sodium and thiaprofenic acid by precipitation reactions with nickel(II) followed by direct determination of the ions in the precipitate or indirect determination of the ions in the filtrate by atomic absorption spectroscopy. Statistical analysis of the results compared to assays used in pharmacopeas and the Amax. methods revealed equal precision and accuracy. Furthermore the assays were also applied for the determination of these drugs in pharmaceutical preparations.
Keywords: Nickel; Flufenamic acid; Mefenamic acid; Tranexamic acid; Furosemide; Diclofenac sodium; Thiaprofenic acid; Atomic Absorption spectrophotomerty Nickel; Flufenamic acid; Mefenamic acid; Tranexamic acid; Furosemide; Diclofenac sodium; Thiaprofenic acid; Atomic Absorption spectrophotomerty

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MDPI and ACS Style

Salem, H.; Kelani, K.; Shalaby, A. Utility of Nickel for Atomic Absorption Spectrophotometric Determination of Selected Acidic Drugs. Sci. Pharm. 2001, 69, 189-201. https://doi.org/10.3797/scipharm.aut-01-20

AMA Style

Salem H, Kelani K, Shalaby A. Utility of Nickel for Atomic Absorption Spectrophotometric Determination of Selected Acidic Drugs. Scientia Pharmaceutica. 2001; 69(2):189-201. https://doi.org/10.3797/scipharm.aut-01-20

Chicago/Turabian Style

Salem, Hesham, Khadiga Kelani, and Abdalla Shalaby. 2001. "Utility of Nickel for Atomic Absorption Spectrophotometric Determination of Selected Acidic Drugs" Scientia Pharmaceutica 69, no. 2: 189-201. https://doi.org/10.3797/scipharm.aut-01-20

APA Style

Salem, H., Kelani, K., & Shalaby, A. (2001). Utility of Nickel for Atomic Absorption Spectrophotometric Determination of Selected Acidic Drugs. Scientia Pharmaceutica, 69(2), 189-201. https://doi.org/10.3797/scipharm.aut-01-20

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