Reaction of Prop-2-ynylamine with Isochromadiones : Formation of Amides
1
Departments of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
2
Departments of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2001, 69(2), 161-166; https://doi.org/10.3797/scipharm.aut-01-17
Submission received: 5 December 2000
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Accepted: 15 March 2001
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Published: 30 June 2001
Abstract
The ring opening of isochromadiones by prop-2-ynylamine was accomplished in non-polar solvents to form N-prop-2-ynylbenzamide-2-acetic acid 3 N-prop-2-ynylhomophthalimide 4. Compound 3 was found out to be an intermediate product in the formation of 4. These compounds were screened for anticonvulsant and antibacterial properties and were found to have no activity.
Keywords:
Isochromadiones; Prop-2-ynylamine; Amide
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MDPI and ACS Style
Usifoh, C.O.; Okunrobo, L.O.; Ukoh, G.C.
Reaction of Prop-2-ynylamine with Isochromadiones : Formation of Amides
. Sci. Pharm. 2001, 69, 161-166.
https://doi.org/10.3797/scipharm.aut-01-17
AMA Style
Usifoh CO, Okunrobo LO, Ukoh GC.
Reaction of Prop-2-ynylamine with Isochromadiones : Formation of Amides
. Scientia Pharmaceutica. 2001; 69(2):161-166.
https://doi.org/10.3797/scipharm.aut-01-17
Chicago/Turabian StyleUsifoh, C. O., L. O. Okunrobo, and G. C. Ukoh. 2001. "
Reaction of Prop-2-ynylamine with Isochromadiones : Formation of Amides
" Scientia Pharmaceutica 69, no. 2: 161-166.
https://doi.org/10.3797/scipharm.aut-01-17
APA StyleUsifoh, C. O., Okunrobo, L. O., & Ukoh, G. C. (2001).
Reaction of Prop-2-ynylamine with Isochromadiones : Formation of Amides
. Scientia Pharmaceutica, 69(2), 161-166.
https://doi.org/10.3797/scipharm.aut-01-17
