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Synthesis of Thienopyridines and Isoquinolines from 6-Amino-1,2-dihydro-4-methyl-2-thioxopyridine-3,5-dicarbonitrile and of Phthalazines from Thieno[3,4-c]pyridazine

1
Department of Chemistry, Faculty of Science, Benha University, Benha, Egypt
2
H. E. J. Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
3
Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2000, 68(4), 389-401; https://doi.org/10.3797/scipharm.aut-00-36
Received: 1 February 2000 / Revised: 22 September 2000 / Accepted: 22 September 2000 / Published: 5 November 2000
Thienopyridine 1 and thienopyridazine 13 have been readily reacted with electron-poor olefins to give isoquinolines and phthalazines, respectively. Some of the obtained compounds were tested for their antimicrobial activity.
Keywords: Diels-Alder reaction; Thienopyridines; Isoquinolines; Thienopyrid-azines, Phthalazines Diels-Alder reaction; Thienopyridines; Isoquinolines; Thienopyrid-azines, Phthalazines
MDPI and ACS Style

Issac, Y.A.; Ali, M.S.; Erian, A.W. Synthesis of Thienopyridines and Isoquinolines from 6-Amino-1,2-dihydro-4-methyl-2-thioxopyridine-3,5-dicarbonitrile and of Phthalazines from Thieno[3,4-c]pyridazine. Sci. Pharm. 2000, 68, 389-401.

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