2000 December - 10 articles
The Contents of Al, Ba, Cr, Cu, Sr, and Zn in Atropa belladonna, Datura stramonium, and Hyoscyamus niger are measured by ICP-AES. Enrichment of these elements in the leaves is observed.
Salvia bucharica belonging to the family Lamiaceae (Labiatae), afforded a new aromatic ester named buchariate [1-(p-hydroxybenzoyloxy)-3-oxo-octane (1)] along with twelve known constituents for the first time from our investigated source. The structu...
From bulbs of Drimia robusta 7 bufadienolides were isolated, 3 of them new natural compounds. Structure elucidation was performed by comparison with authentic substances or by means of 1H-, 13C-NMR-spectroscopy and FAB-MS. The substances were identif...
A simple, rapid and sensitive spectrophotometric procedure for the assay of some drugs has been developed. The method is based on the reaction of the studied drugs with 2,2-diphenyl-1-picrylhydrazyl (DPPH). The latter is employed to abstract a hydrog...
Thienopyridine 1 and thienopyridazine 13 have been readily reacted with electron-poor olefins to give isoquinolines and phthalazines, respectively. Some of the obtained compounds were tested for their antimicrobial activity.
Effects of acute administration of vigabatrin (VGB) that has significant GABA-mimetic properties were studied for its antiinflammatory, antigranuloma effects in rats and thermoregulatory actions in mice. Treatment of rats with VGB (125, 250 and 500 m...
Various 4-substituted phenyl semicarbazone derivatives were synthesized and evaluated in vitro by NCI in the 3-cell line, one dose primary anticancer assay. Three compounds showed significant activity against breast MCF7 cell line and were further ev...
Complexation properties of ranitidine (Ran) with Fe2+, Fe3+, A13+, Mg2+, Cu2+, Ni2+ and Pb2+ were studied using UV/V|S spectroscopy and conductometric titrations respectively. Ranitidine was found to form 1:1 complexes in methanol or aqueous buffer (...
Simple and accurate methods are described for the quantitative determination of flufenamic acid, mefenamic acid and tranexamic acid utilizing precipitation reactions with cobalt, cadmium and manganese. The acidic drugs were precipitated from their ne...
The paper presents the synthesis of 5-substituted pyrimidine sulphonamides as well as the results of studies on the antibacterial and antifungal activity of obtained derivatives.
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