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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Betrachtungen zur Herstellung von Methadon-nitril und Isomethadon-nitril sowie verwandten Verbindungen

Institut für Pharmazeutische Chemie der Westfälischen Wilhelms-Universität Münster, Hittorfstr. 58-62, D-48149 Münster, Bundesrepublik Deutschland
Author to whom correspondence should be addressed.
Sci. Pharm. 2000, 68(3), 229-234;
Received: 16 June 2000 / Revised: 11 July 2000 / Accepted: 11 July 2000 / Published: 24 July 2000
The 2-chloro-1-dialkylamino-propanes 4a-d are reacted with diphenylacetonitrile under phase transfer conditions to give a mixture of the nitriles 1a-d and 2a-d. Both chloro-dialkylamino-1-phenyl-ethanes 7a-d and 8a-d lead to 4-dialkylamino-2,2,3-triphenyl-butyronitriles 6a-d.
Keywords: 4-Dialkylamino-2,2-diphenyl-valeronitriles; 4-dialkylamino-2,2-diphenyl-3-methyl-butyronitriles; 4-dialkylamino-2,2,3-triphenyl-butyronitriles 4-Dialkylamino-2,2-diphenyl-valeronitriles; 4-dialkylamino-2,2-diphenyl-3-methyl-butyronitriles; 4-dialkylamino-2,2,3-triphenyl-butyronitriles
MDPI and ACS Style

Unterhalt, B.; Coesfeld, B. Betrachtungen zur Herstellung von Methadon-nitril und Isomethadon-nitril sowie verwandten Verbindungen. Sci. Pharm. 2000, 68, 229-234.

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