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Diseases, Volume 7, Issue 1

March 2019 - 32 articles

Cover Story: Myogenin–Cre-mediated deletion of the SET and MYND Domain 1 (SMYD1) lysine methyl transferase in skeletal muscle results in perinatal death in mice. Severe defects in pectoral (white arrows) and sternohyoid (yellow arrows) muscles, as well as accumulation of excessive brown adipose tissue (pink), were observed in the conditional knockout (CKO, right) relative to wild-type (WT, left). Dorsal muscles (blue arrows) were also significantly diminished, whereas other skeletal muscles were left unscathed. Shown are the in situ Myogenin hybridization sections at embryonic (E) stage (15.5 days). View this paper.
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Articles (32)

  • Article
  • Open Access
5 Citations
4,524 Views
8 Pages

Handgrip strength (HS) and knee extensor muscle strength (KEMS) showed a negative correlation with the Disabilities of the Arm, Shoulder, and Hand (DASH) score at one month following cardiac surgery. We performed a longitudinal study to examine chang...

  • Communication
  • Open Access
4,613 Views
4 Pages

Ancient Egyptians smeared a mixture of dark soil on their eyelids and believed it protected eyes from unknown forces (illness). Recent studies have proven that the dark soil across the Nile River is rich in natural compounds including lead sulfide, w...

  • Article
  • Open Access
16 Citations
7,678 Views
7 Pages

Keeping an Eye on Perimenopausal and Postmenopausal Endometriosis

  • Michail Matalliotakis,
  • Charoula Matalliotaki,
  • Alexandra Trivli,
  • Maria I. Zervou,
  • Ioannis Kalogiannidis,
  • Maria Tzardi,
  • Ioannis Matalliotakis,
  • Aydin Arici and
  • George N. Goulielmos

Introduction: We aimed to describe and review the epidemiological aspect of the disease pattern of a series of perimenopausal and postmenopausal women with a histology confirmation of endometriosis. Material and Methods: We retrospectively examined t...

  • Review
  • Open Access
80 Citations
19,099 Views
14 Pages

Salmonella not only causes acute infections, but can also cause patients to become chronic “asymptomatic” carriers. Salmonella has been verified as a pathogenic factor that contributes to chronic inflammation and carcinogenesis. This revi...

  • Review
  • Open Access
44 Citations
9,762 Views
12 Pages

The Therapeutic Implications of the Gut Microbiome and Probiotics in Patients with NAFLD

  • Brandon J. Perumpail,
  • Andrew A. Li,
  • Nimy John,
  • Sandy Sallam,
  • Neha D. Shah,
  • Waiyee Kwong,
  • George Cholankeril,
  • Donghee Kim and
  • Aijaz Ahmed

25 February 2019

Recent breakthrough in our understanding pertaining to the pathogenesis of nonalcoholic fatty liver disease (NAFLD) has pointed to dysregulation or derangement of the gut microbiome, also known as dysbiosis. This has led to growing interest in probio...

  • Article
  • Open Access
8 Citations
4,189 Views
9 Pages

24 February 2019

The relationship between hepatitis C virus (HCV) infection and C-reactive protein (CRP), which is an inflammatory biomarker, is limited in studies with the general population. It was hypothesized that changes in CRP levels are genotype-dependent in t...

  • Feature Paper
  • Article
  • Open Access
17 Citations
6,141 Views
16 Pages

Factors Influencing Quality of Life in Breast Cancer Patients Six Months after the Completion of Chemotherapy

  • Maria Lavdaniti,
  • Dimitra Anna Owens,
  • Polixeni Liamopoulou,
  • Kalliopi Marmara,
  • Efrosini Zioga,
  • Michael S. Mantzanas,
  • Eftychia Evangelidou and
  • Eugenia Vlachou

24 February 2019

Purpose: To assess breast cancer patients’ quality of life six months after the completion of adjuvant chemotherapy, and to investigate factors affecting this. Methods: The study was conducted in one large hospital located in a major Greek city...

  • Feature Paper
  • Review
  • Open Access
24 Citations
6,520 Views
12 Pages

Social Interaction Improved by Oxytocin in the Subclass of Autism with Comorbid Intellectual Disabilities

  • Haruhiro Higashida,
  • Toshio Munesue,
  • Hirotaka Kosaka,
  • Hidenori Yamasue,
  • Shigeru Yokoyama and
  • Mitsuru Kikuchi

22 February 2019

Approximately half of all autism spectrum disorder (ASD) individuals suffer from comorbid intellectual disabilities. Furthermore, the prevalence of epilepsy has been estimated to be 46% of patients with low intelligence quotient. It is important to i...

  • Feature Paper
  • Article
  • Open Access
4 Citations
4,829 Views
10 Pages

Inhibitory Effect of Ionizing Radiation on Echinococcus granulosus Hydatid Cyst

  • Yumin Zhao,
  • Weifeng Gui,
  • Yishu Zhang,
  • Gang Mo,
  • Dayu Li and
  • Shigui Chong

18 February 2019

Background: Heavy ion radiation has more advantages than traditional radiation therapy in the treatment of cancer, mainly because of its superior biological effects. However, there is currently no reliable evidence that heavy ion radiation can induce...

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Diseases - ISSN 2079-9721