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Cosmetics, Volume 11, Issue 3

2024 June - 40 articles

Cover Story: Cosmetic formulations based on natural ingredients have received increased consumer attention due to health, safety, and sustainability concerns. European regulations mandate manufacturers to assess the safety of all cosmetic products, including those from natural sources. This assessment includes evaluating microbial and chemical hazards, and the local and systemic risks associated with natural substances. The ban on animal-based toxicological testing for cosmetic ingredients necessitates the rapid adoption, validation, and regulatory acceptance of New Approach Methodologies (NAMs). Additionally, restrictions apply to certain naturally occurring bioactive compounds with allergenic properties. This paper provides an in-depth discussion of the legal and safety aspects of natural cosmetic ingredients and products in the European Union. View this paper
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Articles (40)

  • Article
  • Open Access
4 Citations
4,329 Views
13 Pages

Development of an Antioxidant, Anti-Aging, and Photoprotective Phytocosmetic from Discarded Agave sisalana Perrine Roots

  • Guilherme dos Santos Mazo,
  • Julia Amanda Rodrigues Fracasso,
  • Luísa Taynara Silvério da Costa,
  • Valdecir Farias Ximenes,
  • Natália Alves Zoppe,
  • Amanda Martins Viel,
  • Lucas Pires Guarnier,
  • Beatriz de Castro Silva,
  • Luan Victor Coelho de Almeida and
  • Lucinéia dos Santos

The primary source of hard fiber globally is Agave sisalana Perrine, also known as sisal. In areas where sisal is grown, the roots of the plant are usually left in the field after it has stopped producing, which leads to soil degradation and decrease...

  • Article
  • Open Access
4,016 Views
14 Pages

Establishing the Inhibition of the Serine Protease Plasmin as a Skin Anti-Aging Pathway

  • Remo Campiche,
  • Dominik Imfeld,
  • Chennakesava Cuddapah,
  • Leithe Budel and
  • Mathias Gempeler

Plasmin is a serine protease induced by UV-irradiation in skin that contributes to inflammation. We showed that plasmin is upregulated in photo-exposed facial skin and that this correlates with increased transepidermal water loss (TEWL). Plasmin acti...

  • Article
  • Open Access
5,673 Views
13 Pages

Human hair is characterized by significant diversity, which is dictated by the individual genetic makeup. It is estimated that up to 70% of the world’s population has textured hair, with a significant proportion also living in areas with high e...

  • Article
  • Open Access
5 Citations
15,547 Views
14 Pages

Pigmentary disorders of the face present a significant challenge in dermatology, impacting the confidence and well-being of affected individuals. Various approaches have been developed to address these concerns, including microneedling and topical vi...

  • Article
  • Open Access
1 Citations
6,538 Views
11 Pages

A Split-Face Comparison of Novel Microneedle Patch versus Botulinum Toxin-A and Microneedle Patch for Improvement in Undereye Skin Texture

  • Polen Te,
  • Jitlada Meephansan,
  • Punyaphat Sirithanabadeekul,
  • Purit Pureesrisak,
  • Kittipong Tantisantisom,
  • Sattra Thongma,
  • Yossawat Rayanasukha,
  • Punyanuch Adulyaritthikul and
  • Paisan Khanchaitit

(1) Background: The emergence of microneedle patch technology and its development as a transdermal drug delivery platform have shown proven results in improving skin texture and appearance. This study was conducted to determine the efficacy of the mi...

  • Article
  • Open Access
6 Citations
4,066 Views
22 Pages

Thermophilic Composting as a Means to Evaluate the Biodegradability of Polymers Used in Cosmetic Formulations

  • Timothy W. Gillece,
  • Helen K. Gerardi,
  • Roger L. McMullen,
  • William T. Thompson and
  • Daniel H. Brown

In the last decade, a growing demand for sustainable cosmetic ingredients has yielded numerous biodegradation protocols. While OECD (Organization for Economic Co-operation and Development) aquatic assays are suitable for water-borne chemicals, it is...

  • Communication
  • Open Access
3 Citations
8,278 Views
9 Pages

The effect of lactoferrin on skin was simulated using a recombinant human epidermal model. The anti-inflammatory and soothing effect of lactoferrin was verified using IL-1α and TSLP Elisa assay. The effects of lactoferrin on the expression of r...

  • Article
  • Open Access
4 Citations
5,605 Views
14 Pages

Exploring the In Vitro Antioxidant, Anti-Aging, and Cytotoxic Properties of Kaempferia galanga Linn. Rhizome Extracts for Cosmeceutical Formulations

  • Panikchar Wichayapreechar,
  • Ranit Charoenjittichai,
  • Anchalee Prasansuklab,
  • Maria Pilar Vinardell and
  • Wandee Rungseevijitprapa

Kaempferia galanga Linn. (KG), a member of the family Zingiberaceae, is native to India, and commonly found in China, Indonesia, and Thailand. It has been used as a food condiment, folk medicine, and to relieve skin diseases due to its biological act...

  • Systematic Review
  • Open Access
3 Citations
10,846 Views
16 Pages

How Do Artificial Intelligence, Social Media Platforms and Photo Editing Applications Influence Cosmetic Surgery Choices—Literature Systematic Review and Prospective Study

  • Malek Benamor,
  • Stefana Luca,
  • Jed Bouguila,
  • Oxana Madalina Grosu,
  • Bianca Maria Avadani,
  • Dan Cristian Moraru and
  • Mihaela Pertea

Background: In recent years, social media and AI have indirectly taken control of our daily lives. We bring attention to the impact that social networks, photo-editing applications, and artificial intelligence have on potential patients when they are...

  • Article
  • Open Access
1 Citations
1,997 Views
13 Pages

A Mn (II) Quinoline Complex (4QMn) Mitigates Oxidative Damage Induced by Ultraviolet Radiation and Protein Aggregation

  • Marián Merino,
  • Sonia González,
  • Mª Paz Clares,
  • Enrique García-España and
  • José L. Mullor

Solar radiation, specifically ultraviolet radiation (UVR), is one of the harmful external factors that affect the integrity of the skin upon sun overexposure. Its detrimental effects include skin aging (photoaging), pigmentation disorders, and skin c...

  • Article
  • Open Access
8 Citations
4,631 Views
15 Pages

Chemical Profile and Antioxidant and Tyrosinase Inhibitory Activity of Chamaemelum nobile L. Green Extracts

  • Luciana Maria Polcaro,
  • Antonietta Cerulli,
  • Francesco Montella,
  • Elena Ciaglia,
  • Milena Masullo and
  • Sonia Piacente

The request for skin-whitening agents and bioactive principles able to control hyperpigmentation disorders is continuously growing. Chamomile (Matricaria chamomilla) is used as a remedy for skin diseases, but little is known about the ability of Roma...

  • Article
  • Open Access
1 Citations
3,765 Views
16 Pages

Electrospray-Mangiferin Nanoparticles Gel: A Promising Agent for Sun and Age Defense

  • Neungreuthai Chomchoei,
  • Pimporn Leelapornpisid,
  • Pratchaya Tipduangta,
  • Jakkapan Sirithunyalug,
  • Busaban Sirithunyalug and
  • Pawitrabhorn Samutrtai

UV irradiation causes skin damage and aging. This study aimed to develop and evaluate a gel formulation loaded with electrospray mangiferin nanoparticles (MNPs) as a double-action product with photoprotective and anti-aging properties. The MNPs were...

  • Article
  • Open Access
2 Citations
13,669 Views
14 Pages

The Comparative Efficacy and Safety of 250 μm versus 350 μm Long Microneedle Patch on Under-Eye Skin

  • Apisama Arepagorn,
  • Jitlada Meephansan,
  • Punyaphat Sirithanabadeekul,
  • Kittipong Tantisantisom,
  • Sattra Thongma,
  • Yossawat Rayanasukha,
  • Thitikorn Boonkoom and
  • Paisan Khanchaitit

Background: Microneedle patch (MNP) technology is now applied for many purposes, including transdermal drug delivery and percutaneous collagen induction in the cosmetic and dermatology fields. Previous research showed that a MNP effectively improved...

  • Article
  • Open Access
3,129 Views
13 Pages

Towards the Development of a Cream with Antiviral Properties Targeting Both the Influenza A Virus and SARS-CoV-2

  • Philippe Mangeot,
  • Kristell Lazou,
  • Aurelia Blin,
  • Valerie Gorzelanczyk,
  • Olivier Jeanneton,
  • Chantal Kurfurst,
  • Karl Pays,
  • Bruno Bavouzet,
  • Carine Nizard and
  • Anne-Laure Bulteau
  • + 1 author

Objective: Many severe acute respiratory infections are caused by viral pathogens, and viruses are responsible for a large number of deaths worldwide. Among the most common respiratory viruses are the influenza A virus (IAV) and, more recently, the S...

  • Review
  • Open Access
12 Citations
9,070 Views
28 Pages

Disturbances in the Skin Homeostasis: Wound Healing, an Undefined Process

  • Montserrat Férnandez-Guarino,
  • Jorge Naharro-Rodriguez and
  • Stefano Bacci

This review was written with the aim of examining the effects that cause an insult, such as a wound, to an organ, such as the skin. Before examining the cellular mechanisms relating to wound healing, the reader is invited to read about the structure...

  • Communication
  • Open Access
5 Citations
18,457 Views
10 Pages

The use of low-fluence picosecond (LFPS) 1064 nm neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers, referred to as laser toning, is increasingly acknowledged as an effective treatment for pigmentation disorders in the Asian skin phenotype. This...

  • Communication
  • Open Access
1 Citations
5,365 Views
8 Pages

Deodorant Efficacy of Xylityl Sesquicaprylate Vehiculated into Roll-on and Stick Prototype Formulations

  • Lilian Mussi,
  • André Rolim Baby,
  • Cecilia Nogueira,
  • Flávio Bueno de Camargo Junior and
  • Wagner Vidal Magalhães

Given the burgeoning global market for deodorant products, it is paramount to develop novel, safe, and efficacious molecules that align with the cosmetic industry’s trend toward active compounds sourced from natural, sustainable, and renewable...

  • Article
  • Open Access
1 Citations
9,391 Views
13 Pages

Antioxidants (including Vitamin C, ferulic acid, and phloretin) are among the compounds used in skincare products. The purpose of this study was to evaluate the effect of a combination containing L-ascorbic acid, ferulic acid, and phloretin. The deli...

  • Article
  • Open Access
3 Citations
2,255 Views
18 Pages

Physicochemical Properties of a Bioactive Polysaccharide Film from Cassia grandis with Immobilized Collagenase from Streptomyces parvulus (DPUA/1573)

  • Kétura Ferreira,
  • Kethylen Cardoso,
  • Romero Brandão-Costa,
  • Joana T. Martins,
  • Cláudia Botelho,
  • Anna Neves,
  • Thiago Nascimento,
  • Juanize Batista,
  • Éverton Ferreira and
  • José Teixeira
  • + 4 authors

(1) Background: Polysaccharide films are promising vehicles for the delivery of bioactive agents such as collagenases, as they provide controlled release at the wound site, facilitating tissue regeneration. This study aimed to investigate the physico...

  • Article
  • Open Access
3,732 Views
11 Pages

Nanotechnology for Effective Epilation: Assessment of the Application of a Protease-Containing Microemulsion

  • Monika Skórka,
  • Manfred Gahrtz,
  • Maria D. Chatzidaki,
  • Aristotelis Xenakis and
  • Thomas Whitfield

Background: Epilation is a very effective way to remove unwanted hair because of its long-lasting effects. However, there are some disadvantages such as pain during the procedure, the possibility of ingrown hairs and perifollicular inflammation. In t...

  • Article
  • Open Access
8 Citations
5,168 Views
11 Pages

The increasing use of natural ingredients such as essential oils (EOs) and natural extracts (NEs) in cosmetics is an analytical and legislative challenge due to their complex composition, which includes recognized allergenic compounds. In this work,...

  • Article
  • Open Access
2 Citations
6,204 Views
13 Pages

Background: Eyelid dermatitis is a common, multifactorial, chronic, and/or relapsing condition with a considerable impact on life quality that represents a diagnostic and treatment challenge. Methods: We carried out a single-blind, controlled, random...

  • Article
  • Open Access
2 Citations
4,291 Views
16 Pages

N-acetylneuraminic acid (Neu5Ac) is the predominant form of sialic acid present in the glossy swiftlet (Collocalia esculenta). It is also the only form of sialic acid detected in the human body. In this study, we investigated the mechanism underlying...

  • Article
  • Open Access
1 Citations
13,124 Views
12 Pages

Fractional Ablative Carbon Dioxide Laser versus Fractional Non-Ablative 1410 nm Diode Laser in the Treatment of Acne Scars: A Clinical and Immunohistochemical Study

  • Mai Abdelraouf Osman,
  • Shaimaa Mohamedadel Fawy,
  • Dalia M. Abouelfadl,
  • Mohamed Fouad Abdel Salam,
  • Amin Sharobim and
  • Abeer Attia Tawfik

Background: Effectively managing acne scars while minimizing consequences is still a challenging task. The primary determinant in selecting and continuing therapy for a specific device is stimulating collagen production and dermal remodeling with the...

  • Review
  • Open Access
11 Citations
17,921 Views
19 Pages

Deciphering the Effects of Different Types of Sunlight Radiation on Skin Function: A Review

  • Sophia Letsiou,
  • Elpida Koldiri,
  • Apostolos Beloukas,
  • Efstathios Rallis and
  • Vasiliki Kefala

Sunlight radiation is a fundamental component of our daily lives. Specifically, blue light as well as UV light appear to play a role in the development of oxidative stress, DNA damage, photoaging, and pigmentation through the chromophores in skin tis...

  • Review
  • Open Access
2 Citations
3,884 Views
16 Pages

In the field of the cosmetic industry, significant efforts are made to develop methods that are not only cost effective and time effective but are also environmentally friendly and cruelty free. Cosmetic tests using in vivo animal models are currentl...

  • Review
  • Open Access
4 Citations
23,793 Views
22 Pages

Contact Dermatitis Due to Hair Care Products: A Comprehensive Review

  • Marta Cebolla-Verdugo,
  • Juan Pablo Velasco-Amador and
  • Francisco José Navarro-Triviño

Hair cosmetics are in fashion. Numerous products are commonly used in combination. Frequent allergens are present in hair cosmetics, which, with almost daily use, increase the risk of sensitization. Familiarity with the clinical distribution of the e...

  • Article
  • Open Access
3 Citations
3,790 Views
12 Pages

Effect of Fermentation and Extraction Techniques on the Physicochemical Composition of Copoazú Butter (Theobroma grandiflorum) as an Ingredient for the Cosmetic Industry

  • Luisa L. Orduz-Díaz,
  • Kimberly Lozano-Garzón,
  • Willian Quintero-Mendoza,
  • Raquel Díaz,
  • Juliana E. C. Cardona-Jaramillo,
  • Marcela P. Carrillo,
  • Diana Carolina Guerrero and
  • Maria Soledad Hernández

The Copoazú is a Theobroma species of Amazonian origin, and its derived products have a high content of lipids valuable for both the cosmetic and food industries. The composition of the butter extracted from its seeds can vary depending on the...

  • Review
  • Open Access
7 Citations
13,746 Views
18 Pages

Polyglutamate: Unleashing the Versatility of a Biopolymer for Cosmetic Industry Applications

  • Mónica Serra,
  • Eduardo Gudina,
  • Cláudia Botelho,
  • José António Teixeira and
  • Ana Novo Barros

Polyglutamic acid (PGA), a biopolymer comprising repeating units of glutamic acid, has garnered significant attention owing to its versatile applications. In recent years, microbial production processes have emerged as promising methods for the large...

  • Article
  • Open Access
1 Citations
3,031 Views
13 Pages

The tap water that we normally use contains certain concentrations of free residual chlorine to kill microorganisms and viruses and make it safe for use. Water containing free residual chlorine not only dries out our hair and skin but can also cause...

  • Review
  • Open Access
7 Citations
26,398 Views
21 Pages

Adult Female Acne: Recent Advances in Pathophysiology and Therapeutic Approaches

  • Andreea Amuzescu,
  • Mircea Tampa,
  • Clara Matei and
  • Simona Roxana Georgescu

Adult acne is a chronic inflammatory disease of the pilosebaceous unit characterized by the excessive production of abnormal sebum favoring an imbalance of the skin microbiota and the hyperproliferation of Cutibacterium acnes and other virulent micro...

  • Article
  • Open Access
4 Citations
12,386 Views
12 Pages

Nicotinamide Riboside Ameliorates Hyperpigmentation on Photo-Irradiated Skin

  • Yeon Jae Lee,
  • Seul Gi Jang,
  • Min Jeong Ryu and
  • Seung Hee Choi

Nicotinamide adenine dinucleotide (NAD) is one of the most important and essential components within an organism. Extensive ongoing research is aimed at harnessing its potential in managing diverse diseases by supplying various forms of NAD in its ox...

  • Review
  • Open Access
32 Citations
23,762 Views
21 Pages

Consumer preferences, safety, and sustainability aspects of conventional cosmetic ingredients have contributed to an increase in the demand for natural cosmetic ingredients and products. Naturally derived active cosmetic agents and excipients may com...

  • Article
  • Open Access
4 Citations
31,708 Views
10 Pages

Efficacy and Safety of Monopolar Radiofrequency for Tightening the Skin of Aged Faces

  • JungMin Shin,
  • Yeounkuk Sung,
  • Soyoung Jin,
  • Cho-Long Hwang,
  • Hyunjung Kim,
  • Dongkyun Hong,
  • Kyung Eun Jung,
  • Young-Joon Seo and
  • Young Lee

Background: Monopolar radiofrequency (RF) has emerged as a promising modality for tightening the skin of aged faces. Although many studies have assessed the efficacy of monopolar RF via the clinical evaluation of photographs, few have examined the lo...

  • Article
  • Open Access
2 Citations
7,238 Views
12 Pages

Advancing Lip Augmentation: State-of-the-Art 2D and 3D Analysis for Assessing Volume Enhancement and Lip Line Redefinition

  • Ritamaria Di Lorenzo,
  • Lucia Ricci,
  • Eleonora Vardaro,
  • Teresa Di Serio,
  • Elena Morelli and
  • Sonia Laneri

Over the preceding five decades, there has been a noticeable surge in the pursuit of achieving voluminous and well-defined lips. This trend has prompted an escalating number of individuals to undergo lip augmentation procedures, aiming for a natural...

  • Article
  • Open Access
3 Citations
6,488 Views
11 Pages

Artichoke Leaf Extract Effectiveness on the Skin Aging Exposome: Efficacy and Safety Results of a Split-Face Study

  • Gloria Roveda,
  • Enza Cestone,
  • Francesca De Gennaro,
  • Andrea Poggi,
  • Violetta Insolia,
  • Vincenzo Zaccaria and
  • Vincenzo Nobile

The skin is a barrier organ subjected to lifelong exposure to internal and external factors influencing both its biological response and appearance. A randomized split-face study was carried out on 22 adult female outdoor workers using an artichoke l...

  • Article
  • Open Access
7 Citations
6,005 Views
16 Pages

Development of Cosmetic Formulations Containing Olive Extract and Spirulina sp.: Stability and Clinical Efficacy Studies

  • Gabriela Maria D’Angelo Costa and
  • Patricia Maria Berardo Gonçalves Maia Campos

Cosmetic formulations with natural antioxidants can reduce the oxidative stress caused by solar radiation and pollution. In this context, the aim of this study was to develop and evaluate the clinical efficacy of cosmetic formulations containing oliv...

  • Correction
  • Open Access
1 Citations
1,863 Views
2 Pages
  • Article
  • Open Access
9 Citations
5,651 Views
17 Pages

Stability and Retention of Nanoemulsion Formulations Incorporating Lavender Essential Oil

  • Konstantina Flekka,
  • Virginia D. Dimaki,
  • Elena Mourelatou,
  • Konstantinos Avgoustakis,
  • Fotini N. Lamari and
  • Sophia Hatziantoniou

Lavender essential oil (LEO) is applied topically for its soothing properties, serving not only as an antiseptic in wound care but also as an insect repellent. This study investigates the impact of carrier systems on LEO encapsulation, stability, and...

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Cosmetics - ISSN 2079-9284