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Biosensors, Volume 8, Issue 1

March 2018 - 26 articles

Cover Story: As competitors of neurotransmitters like dopamine (DA), antipsychotic drugs (APD) bind to the receptor sites in neurons and block the biological responses in vivo. Currently available in vitro APD screening platforms are developed on the basis of drug-receptor interaction monitoring with fluorescent or radioactive methods that require lengthy and troublesome labelling steps. In this work, we unraveled the unique potentials of label-free electrochemical and optical biosensors for cost-efficient and simpler APD screening. Specifically, we demonstrate the utility of electrochemical impedance spectroscopy and nanoplasmonic sensing for rapid analysis and identification of APD candidates via drug-receptor in vitro assays. View this paper
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Articles (26)

  • Article
  • Open Access
18 Citations
5,860 Views
9 Pages

The Use of Biosensors to Explore the Potential of Probiotic Strains to Reduce the SOS Response and Mutagenesis in Bacteria

  • Vladimir Anatolievich Chistyakov,
  • Evgeniya Valer’evna Prazdnova,
  • Maria Sergeevna Mazanko and
  • Anzhelica Borisovna Bren

16 March 2018

A model system based on the Escherichia coli MG1655 (pRecA-lux) Lux-biosensor was used to evaluate the ability of the fermentates of eight probiotic strains to reduce the SOS response stimulated by ciprofloxacin in bacteria and mutagenesis mediated b...

  • Feature Paper
  • Article
  • Open Access
16 Citations
6,654 Views
11 Pages

Fabrication of SrTiO3 Layer on Pt Electrode for Label-Free Capacitive Biosensors

  • Francesca Malvano,
  • Luigi Maritato,
  • Giovanni Carapella,
  • Pasquale Orgiani,
  • Roberto Pilloton,
  • Marisa Di Matteo and
  • Donatella Albanese

16 March 2018

Due to their interesting ferroelectric, conductive and dielectric properties, in recent years, perovskite-structured materials have begun to attract increasing interest in the biosensing field. In this study, a strontium titanate perovskite layer (Sr...

  • Feature Paper
  • Review
  • Open Access
92 Citations
15,187 Views
17 Pages

Calibration of Minimally Invasive Continuous Glucose Monitoring Sensors: State-of-The-Art and Current Perspectives

  • Giada Acciaroli,
  • Martina Vettoretti,
  • Andrea Facchinetti and
  • Giovanni Sparacino

13 March 2018

Minimally invasive continuous glucose monitoring (CGM) sensors are wearable medical devices that provide real-time measurement of subcutaneous glucose concentration. This can be of great help in the daily management of diabetes. Most of the commercia...

  • Review
  • Open Access
205 Citations
24,437 Views
34 Pages

Biosensors for Sustainable Food Engineering: Challenges and Perspectives

  • Suresh Neethirajan,
  • Vasanth Ragavan,
  • Xuan Weng and
  • Rohit Chand

12 March 2018

Current food production faces tremendous challenges from growing human population, maintaining clean resources and food qualities, and protecting climate and environment. Food sustainability is mostly a cooperative effort resulting in technology deve...

  • Feature Paper
  • Article
  • Open Access
46 Citations
10,136 Views
8 Pages

Accuracy of Continuous Glucose Monitoring before, during, and after Aerobic and Anaerobic Exercise in Patients with Type 1 Diabetes Mellitus

  • Lyvia Biagi,
  • Arthur Bertachi,
  • Carmen Quirós,
  • Marga Giménez,
  • Ignacio Conget,
  • Jorge Bondia and
  • Josep Vehí

9 March 2018

Continuous glucose monitoring (CGM) plays an important role in treatment decisions for patients with type 1 diabetes under conventional or closed-loop therapy. Physical activity represents a great challenge for diabetes management as well as for CGM...

  • Article
  • Open Access
9 Citations
8,916 Views
12 Pages

A DNA-Based Assay for Digoxin Detection

  • Michael V. Kjelstrup,
  • Line D. F. Nielsen,
  • Malthe Hansen-Bruhn and
  • Kurt V. Gothelf

6 March 2018

The most common method for quantifying small-molecule drugs in blood samples is by liquid chromatography in combination with mass spectrometry. Few immuno-based assays are available for the detection of small-molecule drugs in blood. Here we report o...

  • Article
  • Open Access
13 Citations
8,360 Views
11 Pages

Amperometric Self-Referencing Ceramic Based Microelectrode Arrays for D-Serine Detection

  • Diana Campos-Beltrán,
  • Åsa Konradsson-Geuken,
  • Jorge E. Quintero and
  • Lisa Marshall

6 March 2018

D-serine is the major D-amino acid in the mammalian central nervous system. As the dominant co-agonist of the endogenous synaptic NMDA receptor, D-serine plays a role in synaptic plasticity, learning, and memory. Alterations in D-serine are linked to...

  • Article
  • Open Access
42 Citations
8,362 Views
13 Pages

A Nanostructured Sensor Based on Gold Nanoparticles and Nafion for Determination of Uric Acid

  • Natalia Stozhko,
  • Maria Bukharinova,
  • Leonid Galperin and
  • Khiena Brainina

6 March 2018

The paper discusses the mechanism of uric acid (UA) electrooxidation occurring on the surface of gold nanoparticles. It has been shown that the electrode process is purely electrochemical, uncomplicated with catalytic stages. The nanoeffects observed...

  • Article
  • Open Access
14 Citations
6,508 Views
10 Pages

28 February 2018

Here, we provide a method and apparatus for real-time compensation of the thermal effect of single free-standing piezoresistive microcantilever-based biosensors. The sensor chip contained an on-chip fixed piezoresistor that served as a temperature se...

  • Feature Paper
  • Review
  • Open Access
79 Citations
21,381 Views
30 Pages

26 February 2018

Designs and applications of microfluidics-based devices for molecular diagnostics (Nucleic Acid Amplification Tests, NAATs) in infectious disease testing are reviewed, with emphasis on minimally instrumented, point-of-care (POC) tests for resource-li...

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Biosensors - ISSN 2079-6374Creative Common CC BY license