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Biosensors, Volume 10, Issue 9

September 2020 - 28 articles

Cover Story: Cytokine IL-6 plays a major role in several inflammatory diseases, from rheumatoid arthritis to cancer, and more recently, in COVID-19 pneumonia. In the aim of producing highly sensitive and selective biosensors, we performed a virtual comparison among different IL-6 receptors, two Fabs, an aptamer, a clinical antibody as well as the natural receptors of this protein. The procedure requires translating the biomolecules (the protein alone and complexed with its receptors) into complex elec-trical networks, then allowing a flow of electrons to cross them, in such a way that the electron flux works like a probe exploring the network topology. The selected receptors were ranked accounting for their topological complementarity with IL-6. Two of the analyzed receptors are endorsed in a would-be electrochemical biosensor. View this pa-per.
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Articles (28)

  • Article
  • Open Access
15 Citations
3,841 Views
11 Pages

22 September 2020

A new fluorescent chemosensor for copper (II) and subsequent anion sensing was designed and fully characterized. The sensor consisted of a 1,8-naphthalimide core, bearing two terminal dipicolylamine (DPA) receptor units for binding metal cations, and...

  • Article
  • Open Access
13 Citations
4,705 Views
10 Pages

20 September 2020

Wearable devices equipped with inertial sensors enable objective gait assessment for persons with multiple sclerosis (MS), with potential use in ambulatory care or home and community-based assessments. However, gait data collected in non-controlled s...

  • Review
  • Open Access
105 Citations
11,911 Views
23 Pages

18 September 2020

A recent development in portable biosensors allows rapid, accurate, and on-site detection of biomarkers, which helps to prevent disease spread by the control of sources. Less invasive sample collection is necessary to use portable biosensors in remot...

  • Article
  • Open Access
12 Citations
3,489 Views
19 Pages

16 September 2020

Microfluidic separators based on Deterministic Lateral Displacement (DLD) constitute a promising technique for the label-free detection and separation of mesoscopic objects of biological interest, ranging from cells to exosomes. Owing to the simultan...

  • Article
  • Open Access
15 Citations
4,513 Views
13 Pages

Robust Single-Trial EEG-Based Authentication Achieved with a 2-Stage Classifier

  • Uladzislau Barayeu,
  • Nastassya Horlava,
  • Arno Libert and
  • Marc Van Hulle

13 September 2020

The risk of personal data exposure through unauthorized access has never been as imminent as today. To counter this, biometric authentication has been proposed: the use of distinctive physiological and behavioral characteristics as a form of identifi...

  • Article
  • Open Access
35 Citations
5,889 Views
17 Pages

Screen-Printed Glucose Sensors Modified with Cellulose Nanocrystals (CNCs) for Cell Culture Monitoring

  • Ye Tang,
  • Konstantinos Petropoulos,
  • Felix Kurth,
  • Hui Gao,
  • Davide Migliorelli,
  • Olivier Guenat and
  • Silvia Generelli

13 September 2020

Glucose sensors are potentially useful tools for monitoring the glucose concentration in cell culture medium. Here, we present a new, low-cost, and reproducible sensor based on a cellulose-based material, 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO)...

  • Article
  • Open Access
15 Citations
4,932 Views
12 Pages

11 September 2020

Adenine is an important molecule for biomedical and agricultural research and applications. The detection of low concentration adenine molecules is thus desirable. Surface-enhanced Raman scattering (SERS) is a promising label-free detection and finge...

  • Article
  • Open Access
22 Citations
5,730 Views
8 Pages

Screen-Printed Sensor for Low-Cost Chloride Analysis in Sweat for Rapid Diagnosis and Monitoring of Cystic Fibrosis

  • Alicia Hauke,
  • Susanne Oertel,
  • Leona Knoke,
  • Vanessa Fein,
  • Christoph Maier,
  • Folke Brinkmann and
  • Michael P. M. Jank

11 September 2020

Analysis of sweat chloride levels in cystic fibrosis (CF) patients is essential not only for diagnosis but also for the monitoring of therapeutic responses to new drugs, such as cystic fibrosis transmembrane conductance regulator (CFTR) modulators an...

  • Article
  • Open Access
9 Citations
4,907 Views
12 Pages

LipiSensors: Exploiting Lipid Nanoemulsions to Fabricate Ionophore-Based Nanosensors

  • Alexandra L. Dailey,
  • Meredith D. Greer,
  • Tyler Z. Sodia,
  • Megan P. Jewell,
  • Tabitha A. Kalin and
  • Kevin J. Cash

10 September 2020

Ionophore-based nanosensors (IBNS) are tools that enable quantification of analytes in complex chemical and biological systems. IBNS methodology is adopted from that of bulk optodes where an ion exchange event is converted to a change in optical outp...

  • Review
  • Open Access
21 Citations
5,464 Views
47 Pages

Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review

  • Ana Lúcia Morais,
  • Patrícia Rijo,
  • María Belén Batanero Hernán and
  • Marisa Nicolai

10 September 2020

Over recent three decades, the electrochemical techniques have become widely used in biological identification and detection, because it presents optimum features for efficient and sensitive molecular detection of organic compounds, being able to tra...

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Biosensors - ISSN 2079-6374