Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review
1
CBIOS—Universidade Lusófona Research Centre for Biosciences & Health Technologies, Campo Grande 376, 1749-024 Lisbon, Portugal
2
Department of Biomedical Sciences, Faculty of Pharmacy, University of Alcalá, Ctra. A2, Km 33.600–Campus Universitario, 28871 Alcalá de Henares, Spain
3
iMed.ULisboa-Research Institute for Medicines and Pharmaceutical Sciences, Universidade de Lisboa—Faculdade de Farmácia, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal
4
Department of Organic & Inorganic Chemistry, Faculty of Pharmacy, University of Alcalá, 28805 Madrid, Spain
*
Authors to whom correspondence should be addressed.
†
Current address: Instituto de Investigación Química “Andrés M. del Río” (IQAR) University of Alcala, 28801 Madrid, Spain.
Biosensors 2020, 10(9), 121; https://doi.org/10.3390/bios10090121
Received: 28 July 2020 / Revised: 28 August 2020 / Accepted: 7 September 2020 / Published: 10 September 2020
(This article belongs to the Special Issue Advanced Biosensing Technologies in Medical Applications)
Over recent three decades, the electrochemical techniques have become widely used in biological identification and detection, because it presents optimum features for efficient and sensitive molecular detection of organic compounds, being able to trace quantities with a minimum of reagents and sample manipulation. Given these special features, electrochemical techniques are regularly exploited in disease diagnosis and monitoring. Specifically, amperometric electrochemical analysis has proven to be quite suitable for the detection of physiological biomarkers in monitoring health conditions, as well as toward the control of reactive oxygen species released in the course of oxidative burst during inflammatory events. Besides, electrochemical detection techniques involve a simple and swift assessment that provides a low detection-limit for most of the molecules enclosed biological fluids and related to non-transmittable morbidities.
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Keywords:
non-communicable diseases; electrochemistry; hydrogen peroxide; dopamine; uric acid; ascorbic acid; reactive oxygen species; antioxidants
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MDPI and ACS Style
Morais, A.L.; Rijo, P.; Batanero Hernán, M.B.; Nicolai, M. Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review. Biosensors 2020, 10, 121. https://doi.org/10.3390/bios10090121
AMA Style
Morais AL, Rijo P, Batanero Hernán MB, Nicolai M. Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review. Biosensors. 2020; 10(9):121. https://doi.org/10.3390/bios10090121
Chicago/Turabian StyleMorais, Ana L.; Rijo, Patrícia; Batanero Hernán, María B.; Nicolai, Marisa. 2020. "Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review" Biosensors 10, no. 9: 121. https://doi.org/10.3390/bios10090121
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