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Journal of Functional Biomaterials, Volume 13, Issue 2

June 2022 - 52 articles

Cover Story: Extrusion-based 3D printing of calcium phosphate cements (CPC) enables the fabrication of patient-specific scaffolds for bone substitutes with high biocompatibility. Due to the brittleness of the material, the stability of such open-pore structures cannot always be guaranteed. Through a multi-technological approach combining CPC printing with melt electrowriting (MEW) of polycaprolactone (PCL) microfibers in one automated process, hybrid and interwoven CPC+PCL scaffolds were successfully fabricated. This not only improved the mechanical properties but also showed partially better pore bridging behavior of human mesenchymal stem cells along the PCL-fibers with increasing CPC strand distances, as well as an elevated proliferation level of murine pre-osteoblasts. View this paper
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Articles (52)

  • Article
  • Open Access
17 Citations
4,321 Views
10 Pages

Green Synthesis of Antibacterial Nanocomposite of Silver Nanoparticle-Doped Hydroxyapatite Utilizing Curcuma longa Leaf Extract and Land Snail (Achatina fulica) Shell Waste

  • Is Fatimah,
  • Habibi Hidayat,
  • Gani Purwiandono,
  • Khoirunisa Khoirunisa,
  • Hasna Azizah Zahra,
  • Rahmania Audita and
  • Suresh Sagadevan

Preparation of green synthesized silver nanoparticle (AgNPs)-doped hydroxyapatite (Ag/HA) utilizing Curcuma longa leaf extract and land snail (Achatina fulica) shell waste was performed. Physicochemical characteristics and antibacterial activity of A...

  • Article
  • Open Access
9 Citations
3,758 Views
14 Pages

A fine control over different dimensional scales is a challenging target for material science since it could grant control over many properties of the final material. In this study, we developed a multivariable additive manufacturing process, direct...

  • Case Report
  • Open Access
8 Citations
5,635 Views
12 Pages

Immediate Tooth Autotransplantation with Root Canal Filling and Partially Demineralized Dentin/Cementum Matrix into Congenital Missing Tooth Region

  • Masaru Murata,
  • Yasuhiro Nakanishi,
  • Kaoru Kusano,
  • Yukito Hirose,
  • Junichi Tazaki,
  • Toshiyuki Akazawa and
  • Itaru Mizoguchi

This clinical report describes immediate tooth auto-transplantation with an autograft of partially demineralized dentin/cementum matrix (pDDM), based on an orthodontic treatment plan for a 16-year-old male patient with a congenital missing tooth (#45...

  • Review
  • Open Access
36 Citations
6,380 Views
18 Pages

The current scenario of the quest for microneedles (MNs) with biodegradability and biocompatibility properties is a potential research area of interest. Microneedles are considered to be robust, can penetrate the skin’s deep-seated layers, and...

  • Article
  • Open Access
4 Citations
2,909 Views
23 Pages

Osteoconductive silk fibroin (SF) binders were fabricated for the bone repair of an alveolar cleft defect. Binders were prefigureared by mixing different ratios of a mixture of random coils and SF aggregation with SF fibrils: 100:0 (SFB100), 75:25 (S...

  • Feature Paper
  • Article
  • Open Access
10 Citations
3,844 Views
13 Pages

Effect of a Self-Assembly Peptide on Surface Roughness and Hardness of Bleached Enamel

  • Gabriela de A. P. Magalhães,
  • May Anny A Fraga,
  • Isaac J. de Souza Araújo,
  • Rafael R. Pacheco,
  • Américo B. Correr and
  • Regina M. Puppin-Rontani

After bleaching, enamel surfaces are damaged, contributing to erosion and tooth sensitivity. Although fluoride is used after bleaching to try and revert alterations, it is not capable of repairing tooth structure. This study compared the effect of a...

  • Article
  • Open Access
15 Citations
3,398 Views
14 Pages

Cu2+ Release from Polylactic Acid Coating on Titanium Reduces Bone Implant-Related Infection

  • Chengdong Zhang,
  • Xingping Li,
  • Dongqin Xiao,
  • Qiao Zhao,
  • Shuo Chen,
  • Fei Yang,
  • Jinhui Liu and
  • Ke Duan

Implant-related infection (IRI) is a major problem in orthopedics. Copper (Cu) is an essential trace element with strong bactericidal activity and, thus, presents potential for reducing IRI. The present study explored a straightforward strategy for r...

  • Review
  • Open Access
166 Citations
15,601 Views
28 Pages

Graphene Oxide (GO) Materials—Applications and Toxicity on Living Organisms and Environment

  • Aminah N. Ghulam,
  • Otávio A. L. dos Santos,
  • Layla Hazeem,
  • Bianca Pizzorno Backx,
  • Mohamed Bououdina and
  • Stefano Bellucci

Graphene-based materials have attracted much attention due to their fascinating properties such as hydrophilicity, high dispersion in aqueous media, robust size, high biocompatibility, and surface functionalization ability due to the presence of func...

  • Article
  • Open Access
18 Citations
4,739 Views
24 Pages

3D Plotting of Calcium Phosphate Cement and Melt Electrowriting of Polycaprolactone Microfibers in One Scaffold: A Hybrid Additive Manufacturing Process

  • David Kilian,
  • Max von Witzleben,
  • Matthew Lanaro,
  • Cynthia S. Wong,
  • Corina Vater,
  • Anja Lode,
  • Mark C. Allenby,
  • Maria A. Woodruff and
  • Michael Gelinsky

The fabrication of patient-specific scaffolds for bone substitutes is possible through extrusion-based 3D printing of calcium phosphate cements (CPC) which allows the generation of structures with a high degree of customization and interconnected por...

  • Article
  • Open Access
4 Citations
4,361 Views
13 Pages

Collagenase Administration into Periodontal Ligament Reduces the Forces Required for Tooth Extraction in an Ex situ Porcine Jaw Model

  • Ran Tohar,
  • Hen Alali,
  • Tamar Ansbacher,
  • Tamar Brosh,
  • Inbal Sher,
  • Yossi Gafni,
  • Evgeny Weinberg and
  • Maayan Gal

Minimally invasive exodontia is among the long-sought-for development aims of safe dental medicine. In this paper, we aim, for the first time, to examine whether the enzymatic disruption of the periodontal ligament fibers reduces the force required f...

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J. Funct. Biomater. - ISSN 2079-4983