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Article

Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol

1
Department of Dental Techniques, Faculty of Midwifery and Medical Assisting (FMAM), “Carol Davila” University of Medicine and Pharmacy, 8, Eroilor Sanitari Blvd, 050474 Bucharest, Romania
2
Department of Analytical Chemistry, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Polizu St., sector 1, 011061 Bucharest, Romania
3
Department of Behavioral Science, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, 19 Plevnei Ave., 010221 Bucharest, Romania
4
Center for Surface Science and Nanotechnology (CSSNT), University Politehnica of Bucharest, 313 Splaiul Independentei, District 6, 060032 Bucharest, Romania
5
Department of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Esenler-Istanbul 34210, Turkey
6
Academy of Romanian Scientists, Splaiul Independentei 54, 050094 Bucharest, Romania
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
J. Clin. Med. 2020, 9(2), 324; https://doi.org/10.3390/jcm9020324
Received: 31 December 2019 / Revised: 15 January 2020 / Accepted: 20 January 2020 / Published: 23 January 2020
The present study aimed to assess the eighteen month follow-up patient-centered outcomes of a simple and predictable protocol for 3D-printed functional complete dentures manufactured using an improved poly(methyl methacrylate) (PMMA)–nanoTiO2. A detailed morphological and structural characterization of the PMMA–TiO2 nanocomposite, using SEM, EDX, XRD, and AFM, after 3D-printing procedure and post-wearing micro-CT, was also performed. Methods: A total of 35 fully edentulous patients were enrolled in this prospective study. A 0.4% TiO2-nanoparticle-reinforced PMMA composite with improved mechanical strength, morphologically and structurally characterized, was used according to an additive computer-aided design and computer-aided manufacturing (CAD/CAM) protocol for complete denture fabrication. The protocol proposed involved a three-step appointment process. Before denture insertion, 1 week, 12 month, and 18-month follow up patients were evaluated via the Visual Analogue Scale (VAS, 0–10) and Oral Health Impact Profile for Edentulous Patients (OHIP-EDENT), with a higher score meaning poor quality of life. Results: A total of 45 complete denture sets were inserted. OHIP-EDENT scored significantly better after 18 months of denture wearing, 20.43 (±4.42) compared to 52.57 (±8.16) before treatment; mean VAS was improved for all parameters assessed. Conclusions: Within the limitations of this study, we can state that the proposed workflow with the improved material used is a viable treatment option for patients diagnosed with complete edentulism. View Full-Text
Keywords: PMMA–nanotitania composite; OHIP-EDENT; digital light processing; complete denture; quality of life PMMA–nanotitania composite; OHIP-EDENT; digital light processing; complete denture; quality of life
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MDPI and ACS Style

Cristache, C.M.; Totu, E.E.; Iorgulescu, G.; Pantazi, A.; Dorobantu, D.; Nechifor, A.C.; Isildak, I.; Burlibasa, M.; Nechifor, G.; Enachescu, M. Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol. J. Clin. Med. 2020, 9, 324. https://doi.org/10.3390/jcm9020324

AMA Style

Cristache CM, Totu EE, Iorgulescu G, Pantazi A, Dorobantu D, Nechifor AC, Isildak I, Burlibasa M, Nechifor G, Enachescu M. Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol. Journal of Clinical Medicine. 2020; 9(2):324. https://doi.org/10.3390/jcm9020324

Chicago/Turabian Style

Cristache, Corina Marilena, Eugenia Eftimie Totu, Gabriela Iorgulescu, Aida Pantazi, Dorel Dorobantu, Aurelia Cristina Nechifor, Ibrahim Isildak, Mihai Burlibasa, Gheorghe Nechifor, and Marius Enachescu. 2020. "Eighteen Months Follow-Up with Patient-Centered Outcomes Assessment of Complete Dentures Manufactured Using a Hybrid Nanocomposite and Additive CAD/CAM Protocol" Journal of Clinical Medicine 9, no. 2: 324. https://doi.org/10.3390/jcm9020324

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