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Journal of Clinical Medicine, Volume 14, Issue 9

May-1 2025 - 406 articles

Cover Story: This review examines acute cardiorenal syndrome (CRS) through a clinical lens, providing practical diagnostic and treatment strategies. It incorporates thoracic and venous excess ultrasound to assess congestion at the bedside and clarifies the clinical significance of rising serum creatinine during diuresis, distinguishing transient changes from true renal injury. It outlines a systematic approach to overcoming diuretic resistance, including natriuresis-guided sequential nephron blockade, ultrafiltration, and inotropic support. We also discuss emerging trials that address renal hypoperfusion and systemic venous congestion. This paper provides evidence-based guidance to support clinicians in making timely and effective decisions to improve patient outcomes in acute CRS. View this paper
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Articles (406)

  • Article
  • Open Access
1 Citations
1,150 Views
12 Pages

Background: The deep inferior epigastric artery perforator (DIEP) flap is currently the most widely used method for autologous breast reconstruction. Its primary advantage over the transverse rectus abdominis muscle (TRAM) flap is the reduction in do...

  • Article
  • Open Access
3 Citations
1,098 Views
10 Pages

Guideline-Directed Medical Therapy in Sepsis Survivors with Left Ventricular Systolic Dysfunction: An Observational Study

  • Thomas Oswald,
  • Samuel Malomo,
  • Thomas Alway,
  • Stanislav Hadjivassilev,
  • Steven Coombs,
  • Susan Ellery,
  • Joon Lee,
  • Claire Phillips,
  • Barbara Philips and
  • Rachael James
  • + 3 authors

Background: Sepsis survivors can develop left ventricular systolic dysfunction (LVSD) and heart failure. These patients are often treated with guideline-directed medical therapy (GDMT) known to be effective in patients with non-sepsis-related heart f...

  • Article
  • Open Access
1,063 Views
25 Pages

Demographic and Socio-Economic Disparities in the Outcomes Among Patients with NVAF Treated with Oral Anticoagulants: A Real-World Evaluation of Medicare Beneficiaries

  • Nipun Atreja,
  • Anandkumar Dubey,
  • Monal Kohli,
  • Jenny Jiang,
  • Melissa Hagan,
  • Gideon Aweh,
  • Shayna Adams and
  • Dong Cheng

Objectives: To assess the association between apixaban use and the risk of stroke/systemic embolism (SE) and major bleeding (MB) compared with other anticoagulants (OACs) across demographic and socio-economic subgroups in the treatment of nonvalvular...

  • Article
  • Open Access
708 Views
15 Pages

The Role of Periarticular Knee Muscle Torques in Ensuring the Body Balance of Older Adults with Balance Disturbances

  • Piotr Prochor,
  • Łukasz Magnuszewski,
  • Paulina Zalewska,
  • Michał Świętek,
  • Zyta Beata Wojszel and
  • Szczepan Piszczatowski

Background: The role of the periarticular muscles of the knee joint in ensuring body balance is still ambiguous. Therefore, we conducted clinical and biomechanical assessments on 52 older adults (36 women and 16 men, age of 67.58 ± 7.30 years,...

  • Systematic Review
  • Open Access
4 Citations
2,970 Views
27 Pages

Comparative Efficacy and Precision of Robot-Assisted vs. Conventional Total Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Ümit Mert,
  • Moh’d Yazan Khasawneh,
  • Maher Ghandour,
  • Ahmad Al Zuabi,
  • Klemens Horst,
  • Frank Hildebrand,
  • Bertil Bouillon,
  • Mohamad Agha Mahmoud and
  • Koroush Kabir

Background/Objectives: Total knee arthroplasty (TKA) is a common procedure for knee osteoarthritis. While conventional TKA (C-TKA) remains standard, robot-assisted TKA (RA-TKA) has been introduced to enhance implant positioning and clinical outcomes....

  • Review
  • Open Access
11 Citations
3,769 Views
32 Pages

Atrial Cardiomyopathy in Atrial Fibrillation: Mechanistic Pathways and Emerging Treatment Concepts

  • Paschalis Karakasis,
  • Panagiotis Theofilis,
  • Panayotis K. Vlachakis,
  • Nikolaos Ktenopoulos,
  • Dimitrios Patoulias,
  • Antonios P. Antoniadis and
  • Nikolaos Fragakis

Atrial fibrillation (AF) is increasingly recognized not merely as an arrhythmia, but as a clinical manifestation of atrial cardiomyopathy (AtCM)—a progressive, multifaceted disease of the atrial myocardium involving structural, electrical, mech...

  • Systematic Review
  • Open Access
2 Citations
2,061 Views
19 Pages

Risk Factors for Prenatal Anxiety in European Women: A Review

  • Alba Val,
  • Cristina M. Posse and
  • M. Carmen Míguez

Background: Prenatal anxiety is a common problem affecting a large number of women. The presence of anxiety during pregnancy is associated with adverse consequences for both the mother and the baby. The main objective of this review was to determine...

  • Article
  • Open Access
1,378 Views
13 Pages

Impact of Frailty and Other Factors as Estimated by HU to Predict Response to Anabolic Bone Medications

  • Abdelrahman M. Hamouda,
  • Zach Pennington,
  • Rahul Kumar,
  • Michael L. Martini,
  • Derrick Obiri-Yeboah,
  • Maria Astudillo Potes,
  • Nicholas Kendall,
  • Anthony L. Mikula,
  • Michelle J. Clarke and
  • William E. Krauss
  • + 7 authors

Introduction: Bone health optimization is a key component of the preoperative management of spine surgery patients, as poor bone quality increases the odds of mechanical complications. The present study aimed to achieve the following: (1) compare the...

  • Article
  • Open Access
1,216 Views
9 Pages

Radiological Evaluation of Retained Primary Molars in Adolescents with Mandibular Second Premolar Agenesis

  • Dita Meistere,
  • Aleksandra Karkle,
  • Sindija Mengele,
  • Liga Kronina and
  • Laura Neimane

Objectives: We aimed to evaluate the condition of retained primary molars in case of mandibular second premolar agenesis. Materials and Methods: In total, 2692 panoramic radiographs of adolescent patients were analyzed to determine the prevalence of...

  • Case Report
  • Open Access
939 Views
7 Pages

Perioperative Stroke in MCA Aneurysm Surgery: The Hidden Risks of Amphetamine Use

  • Firat Taskaya,
  • Vanessa Magdalena Swiatek,
  • Sifian Al-Hamid,
  • Julius Reiser,
  • Roland Schwab,
  • Klaus-Peter Stein,
  • Daniel Behme,
  • Ali Rashidi,
  • I. Erol Sandalcioglu and
  • Belal Neyazi

Background/Objectives: Perioperative strokes are a rare but recognized complication of cerebral aneurysm surgeries, often influenced by patient-specific factors. Amphetamine abuse, known for its vasospastic effects, is an underexplored risk factor in...

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J. Clin. Med. - ISSN 2077-0383