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Journal of Clinical Medicine, Volume 14, Issue 9

May-1 2025 - 406 articles

Cover Story: This review examines acute cardiorenal syndrome (CRS) through a clinical lens, providing practical diagnostic and treatment strategies. It incorporates thoracic and venous excess ultrasound to assess congestion at the bedside and clarifies the clinical significance of rising serum creatinine during diuresis, distinguishing transient changes from true renal injury. It outlines a systematic approach to overcoming diuretic resistance, including natriuresis-guided sequential nephron blockade, ultrafiltration, and inotropic support. We also discuss emerging trials that address renal hypoperfusion and systemic venous congestion. This paper provides evidence-based guidance to support clinicians in making timely and effective decisions to improve patient outcomes in acute CRS. View this paper
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Articles (406)

  • Article
  • Open Access
1,144 Views
9 Pages

Breast Cancer Treatment Disparities in a Rural Setting: Conserving Surgery Versus Mastectomy

  • Benjamin C. Kensing,
  • Lutfi A. Barghuthi,
  • Marvin Heck,
  • Carly R. Wadle,
  • Rebecca J. Swindall,
  • Alan D. Cook and
  • Hishaam N. Ismael

Background/Objectives: Randomized controlled trials demonstrate comparable survival among early-stage breast cancer patients undergoing breast-conserving therapy or patient preference mastectomy. Many factors affect the choice of treatment like the a...

  • Review
  • Open Access
2 Citations
2,045 Views
13 Pages

Modern Biomarkers in IgA Nephropathy and Their Potential in Paediatric Research

  • Agnieszka Such-Gruchot,
  • Małgorzata Mizerska-Wasiak,
  • Emilia Płatos and
  • Małgorzata Pańczyk-Tomaszewska

Immunoglobulin A nephropathy (IgAN) is one of the most common forms of glomerulonephritis and one of the main causes of end-stage renal disease (ESRD), affecting up to 40% of patients after 20 years of the disease. Over the past few years, several st...

  • Systematic Review
  • Open Access
1 Citations
1,571 Views
17 Pages

Artificial Intelligence Methods in the Detection of Oral Diseases on Pantomographic Images—A Systematic Narrative Review

  • Katarzyna Zaborowicz,
  • Maciej Zaborowicz,
  • Katarzyna Cieślińska,
  • Agata Daktera-Micker,
  • Marcel Firlej and
  • Barbara Biedziak

Background: Artificial intelligence (AI) is playing an increasingly important role in everyday dental practice and diagnosis, especially in the area of analysing digital pantomographic images. Through the use of innovative and modern algorithms, clin...

  • Article
  • Open Access
1,957 Views
10 Pages

A Novel Prophylactic Device Against Head Deformity to Prevent Severe Positional Plagiocephaly

  • Yukari Tanaka,
  • Hiroshi Miyabayashi,
  • Takanori Noto,
  • Risa Kato,
  • Nobuhiko Nagano and
  • Ichiro Morioka

Background/Objectives: Preventing head deformity in the early postnatal period could avert positional plagiocephaly (PP). Accordingly, we developed a novel prophylactic device to prevent head deformity and examined its impact on the incidence of PP a...

  • Article
  • Open Access
814 Views
11 Pages

Background: Patients with myasthenia gravis (MG) are susceptible to fractures due to glucocorticoid (GC) use and disease-related functional impairment affecting activities of daily living (ADL). The Fracture Risk Assessment Tool (FRAX®) estimates...

  • Review
  • Open Access
3 Citations
4,088 Views
16 Pages

Background: Intraoperative nerve monitoring (IONM) is increasingly recognized as an essential technique in thyroid surgery to preserve the integrity of the recurrent laryngeal nerve (RLN) and prevent postoperative complications. Although widely adopt...

  • Feature Paper
  • Article
  • Open Access
3 Citations
1,276 Views
17 Pages

Tranilast Reduces Intestinal Ischemia Reperfusion Injury in Rats Through the Upregulation of Heme-Oxygenase (HO)-1

  • Emilio Canovai,
  • Ricard Farré,
  • Gert De Hertogh,
  • Antoine Dubois,
  • Tim Vanuytsel,
  • Jacques Pirenne and
  • Laurens J. Ceulemans

Background: Intestinal ischemia reperfusion injury (IRI) is a harmful process that occurs during intestinal infarction and intestinal transplantation (ITx). It is characterized by severe inflammation which disrupts the mucosal barrier, causing bacter...

  • Article
  • Open Access
860 Views
13 Pages

Characteristics and Outcomes of New-Onset Cardiomyopathy in Hospitalized COVID-19 Patients

  • Sachin Kumar,
  • Gautam Shah,
  • Raunak Nair,
  • Sarah Rikabi,
  • Mohannad Seif,
  • Bindesh Ghimire,
  • Brian Griffin and
  • Umesh N. Khot

Background: The association between Coronavirus Disease-2019 (COVID-19) and new-onset cardiomyopathy (NOC) is unclear. Objectives: We aim to assess the incidence of NOC in hospitalized COVID-19 patients and its impact on short- and long-term survival...

  • Article
  • Open Access
3 Citations
1,204 Views
20 Pages

Cardio-Oncology Challenges in Elderly Patients

  • Ester Topa,
  • Eliana De Rosa,
  • Alessandra Cuomo,
  • Francesco Curcio,
  • Marika Rizza,
  • Francesco Elia,
  • Veronica Flocco,
  • Umberto Attanasio,
  • Martina Iengo and
  • Francesco Fiore
  • + 20 authors

Background and Objectives: Along with the ageing of the population, cancer and cardiovascular (CV) diseases more frequently coexist, complicating patients’ management. Here, we focus on elderly oncologic patients, describing clinical features a...

  • Review
  • Open Access
1 Citations
3,351 Views
13 Pages

The diagnostic evaluation of interstitial lung diseases (ILDs) remains challenging due to their heterogeneous etiologies and overlapping clinical and radiographic patterns. A confident diagnosis often necessitates histopathological sampling, particul...

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J. Clin. Med. - ISSN 2077-0383