jcm-logo

Journal Browser

Journal Browser

Cardiovascular Issues in Critical Care

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: closed (20 May 2025) | Viewed by 565

Special Issue Editors


E-Mail Website
Guest Editor
General University Hospital of Larissa, University of Thessaly Faculty of Medicine, 41110 Larissa, Greece
Interests: critical care; ARDS; mechanical ventilation; sepsis; hemodynamics; echocardiography; arrythmias; cardiomyopathy; neuromonitoring; COVID-19
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
General University Hospital of Larissa, University of Thessaly Faculty of Medicine, 41110 Larissa, Greece
Interests: ARDS; mechanical ventilation; sepsis; hemodynamics; echocardiography; respiratory muscles; diaphragm; esophageal pressure; neuromonitoring; COVID-19
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The Journal of Clinical Medicine has launched a Special Issue entitledCardiovascular Issues in Critical Care”.

Circulatory failure is encompassed in almost every patient in intensive care units, with sepsis being the most common cause, but cardiogenic circulatory failure, hypovolemia, and other types of distributive shock and obstructive shock are also causative agents. Evaluation of precipitating factors, but also understanding the underlying pathophysiological mechanisms of cardiovascular acclimatization to different conditions, is pivotal, governing therapeutic decisions. Tachyarrhythmias are common, and atrial fibrillation may be observed in as many as 25% of critically ill patients, associated with increased length of ventilation and mortality. 

Recent technological developments allow for better hemodynamic monitoring in patients using less invasive devices. One of these, echocardiography, has gained wide acceptance in recent years to guide decisions and critical care management. Optimization of macro- and microcirculation is the ultimate goal through enhancements in blood flow, pressure, and ventriculoarterial coupling using fluids and vasoactive drugs.

From this perspective, we are launching a call for original contributions and review articles addressing any cardiovascular aspects of critically ill patients.

Prof. Dr. Epaminondas G. Zakynthinos
Dr. Vasiliki Tsolaki
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • circulatory failure
  • hemodynamic monitoring
  • heart–lung interactions
  • shock
  • ultrasonography
  • cardiomyopathy
  • septic shock
  • cardiogenic shock
  • tachyarrhythmias
  • atrial fibrillation
  • right ventricular function
  • left ventricular function
  • fluid responsiveness

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 1811 KiB  
Article
Characteristics and Outcomes of New-Onset Cardiomyopathy in Hospitalized COVID-19 Patients
by Sachin Kumar, Gautam Shah, Raunak Nair, Sarah Rikabi, Mohannad Seif, Bindesh Ghimire, Brian Griffin and Umesh N. Khot
J. Clin. Med. 2025, 14(9), 3258; https://doi.org/10.3390/jcm14093258 - 7 May 2025
Viewed by 291
Abstract
Background: The association between Coronavirus Disease-2019 (COVID-19) and new-onset cardiomyopathy (NOC) is unclear. Objectives: We aim to assess the incidence of NOC in hospitalized COVID-19 patients and its impact on short- and long-term survival. Methods: We retrospectively studied 2219 COVID-19 patients hospitalized between [...] Read more.
Background: The association between Coronavirus Disease-2019 (COVID-19) and new-onset cardiomyopathy (NOC) is unclear. Objectives: We aim to assess the incidence of NOC in hospitalized COVID-19 patients and its impact on short- and long-term survival. Methods: We retrospectively studied 2219 COVID-19 patients hospitalized between March 2020 and February 2022 who underwent an in-hospital echocardiogram. NOC was defined as a left-ventricular ejection fraction (LVEF) reduction of >10%, resulting in an LVEF of <54% for females and <52% for males. The 30-day and 1-year survival outcomes in patients without and with NOC were studied. Results: Among 25,943 hospitalized COVID-19 patients, 2219 met our inclusion criteria, with 209 (9.4%) having NOC. NOC patients were more likely to be male (56.1% vs. 68.4%, p = 0.001) and have chronic kidney disease (51.4% vs. 60.3%, p = 0.018). They had a higher 30-day mortality rate (29.1% vs. 32%, p = 0.033), but the 1-year survival rate was similar between the patients without and with NOC (36.9% vs. 41.6%, p = 0.12). Multivariable regression revealed that advanced age, admission to intensive care unit, mechanical ventilation, treatment with glucocorticoids, and treatment with vasopressors were associated with higher odds of 30-day mortality in NOC patients. Only 74 (35.4%) NOC patients had follow-up echocardiograms after discharge, of which 47 showed persistent cardiomyopathy. Conclusions: NOC can affect around 1 out of 10 hospitalized COVID-19 patients undergoing echocardiography. While NOC was associated with worse short-term survival, it did not impact the long-term mortality of these patients. Persistent LVEF deficits in some patients emphasize the need for improved outpatient follow-up to identify at-risk individuals and optimize treatment. Full article
(This article belongs to the Special Issue Cardiovascular Issues in Critical Care)
Show Figures

Figure 1

Back to TopTop