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Journal of Clinical Medicine, Volume 14, Issue 24

December-2 2025 - 41 articles

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Articles (36)

  • Article
  • Open Access

Managing Complex Chronic Otitis Media: Insights from Subtotal Petrosectomy with Blind Sac Closure

  • Angelo Immordino,
  • Simone Oliva,
  • Palmira Immordino,
  • Federico Sireci,
  • Francesco Lorusso,
  • Riccardo Manzella,
  • Salvatore Gallina,
  • Antonino Maniaci,
  • Giannicola Iannella and
  • Quentin Mat
  • + 1 author
J. Clin. Med.2025, 14(24), 8633;https://doi.org/10.3390/jcm14248633 
(registering DOI)

5 December 2025

Objectives: Chronic otitis media poses a surgical challenge, and subtotal petrosectomy represents a last-resort intervention. This study aims to evaluate the efficacy and safety of subtotal petrosectomy with blind sac closure of the external auditory...

  • Review
  • Open Access
J. Clin. Med.2025, 14(24), 8631;https://doi.org/10.3390/jcm14248631 
(registering DOI)

5 December 2025

Prostatic artery embolization (PAE) has emerged as a minimally invasive treatment for benign prostatic obstruction (BPO), offering clinically meaningful symptom improvement with a favorable perioperative safety and sexual function profile. This narra...

  • Article
  • Open Access

Bowel Transit Time May Be Accelerated in Colonic Diverticulosis Independent of Mucosal Serotonin Signaling

  • Piotr Nehring,
  • Miłosz Jastrzębski,
  • Ilona Joniec-Maciejak,
  • Adriana Wawer and
  • Adam Przybyłkowski
J. Clin. Med.2025, 14(24), 8626;https://doi.org/10.3390/jcm14248626 
(registering DOI)

5 December 2025

Background/Objectives: Colonic diverticulosis is a common condition in the elderly population and may affect bowel habits and reduce quality of life. Intestinal peristalsis is regulated by bioamines, which can influence bowel transit time. Methods: T...

  • Systematic Review
  • Open Access

The Association Between Vitamin D Levels and Erectile Dysfunction in Men: A Systematic Review

  • Radvilė Matukaitienė,
  • Augustė Pikelytė,
  • Birutė Žilaitienė,
  • Robertas Lažauskas,
  • Rasa Verkauskienė and
  • Jonas Čeponis
J. Clin. Med.2025, 14(24), 8630;https://doi.org/10.3390/jcm14248630 
(registering DOI)

5 December 2025

Background/Objectives: Erectile dysfunction (ED) is a common sexual disorder in men, frequently linked to endothelial dysfunction affecting penile vasculature. Accumulating evidence suggests that vitamin D (VD) status may influence endothelial functi...

  • Article
  • Open Access
J. Clin. Med.2025, 14(24), 8628;https://doi.org/10.3390/jcm14248628 
(registering DOI)

5 December 2025

Background/Objectives: Stress experienced by pregnant women during the pandemic may be associated with an increased level of fear of childbirth. Psycho-social resources such as a sense of coherence and social support may be associated with better psy...

  • Review
  • Open Access

Modern Imaging Techniques for Percutaneous Coronary Intervention Guidance: A Focus on Intravascular Ultrasound and Optical Coherence Tomography

  • Lorenzo Scalia,
  • Mattia Squillace,
  • Antonio Popolo Rubbio,
  • Enrico Poletti,
  • Federica Agnello,
  • Antonio Sisinni,
  • Francesco Bedogni,
  • Marco Barbanti and
  • Luca Testa
J. Clin. Med.2025, 14(24), 8627;https://doi.org/10.3390/jcm14248627 
(registering DOI)

5 December 2025

The use of imaging during percutaneous coronary intervention (PCI) can improve the outcomes by giving key information in every phase of the procedure. It can improve the knowledge of plaque composition thus helping the subsequent technical strategy;...

  • Article
  • Open Access
J. Clin. Med.2025, 14(24), 8625;https://doi.org/10.3390/jcm14248625 
(registering DOI)

5 December 2025

Background: Cognitive impairment is a major health problem, so several studies worldwide have studied its aggravating and protective factors. However, few studies have looked into the prediction of better or worsening cognitive status based on the pr...

  • Article
  • Open Access

Risk Analysis in the Lower Silesia Healthy Donors Cohort: Statistical Insights and Machine Learning Classification

  • Przemysław Wieczorek,
  • Magdalena Krupińska,
  • Patrycja Gazinska and
  • Agnieszka Matera-Witkiewicz
J. Clin. Med.2025, 14(24), 8624;https://doi.org/10.3390/jcm14248624 
(registering DOI)

5 December 2025

Background/Objectives: Metabolic syndrome (MetS) increases the risk of type 2 diabetes and cardiovascular disease. We aimed to identify the key metabolic predictors of MetS in a Central European cohort and to compare classical statistics with modern...

  • Article
  • Open Access

Dynamics of Fecal microRNAs Following Fecal Microbiota Transplantation in Alcohol-Related Cirrhosis

  • Cristian Ichim,
  • Adrian Boicean,
  • Samuel Bogdan Todor,
  • Ioana Boeras,
  • Paula Anderco and
  • Victoria Birlutiu
J. Clin. Med.2025, 14(24), 8623;https://doi.org/10.3390/jcm14248623 
(registering DOI)

5 December 2025

Background: Micro-RNAs (miRNAs) are emerging as pivotal regulators of pathophysiological processes, reflecting systemic responses to stress, inflammation and metabolic imbalance. Their role in advanced liver disease and in modulating responses to the...

  • Article
  • Open Access

Left Atrial Deformation in Paediatric Dilated and Hypertrophic Cardiomyopathy: Insights from Two-Dimensional Speckle-Tracking Echocardiography

  • Iolanda Muntean,
  • Beatrix-Julia Hack,
  • Diana-Ramona Iurian,
  • Theodora Benedek,
  • Diana Muntean,
  • Ioana-Octavia Matacuta-Bogdan and
  • Asmaa Carla Hagau
J. Clin. Med.2025, 14(24), 8622;https://doi.org/10.3390/jcm14248622 
(registering DOI)

5 December 2025

Background: Left atrial strain (LAS) derived from speckle-tracking echocardiography (STE) provides a sensitive, load-dependent measure of atrial function and ventricular filling pressures. Data on LAS in paediatric cardiomyopathies are still scarce;...

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J. Clin. Med. - ISSN 2077-0383