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Journal of Clinical Medicine, Volume 13, Issue 14

July-2 2024 - 288 articles

Cover Story: There is a well-established relationship between different subsets of idiopathic inflammatory myopathies (IIMs, myositis) and interstitial lung disease (ILD), with lung complications sometimes presenting prior to myopathic manifestations. The subtypes of myositis include those that are strongly associated with ILD. Research has shown that in certain patients, these can then be further divided into subtypes using myositis-specific antibodies (MSAs), which are specific for myositis, and myositis-associated antibodies (MAAs), which can be found in myositis in overlap syndromes with other connective tissue diseases (CTDs). The aim of this review is to highlight the clinical features, diagnostic criteria, important histopathologic, laboratory, and radiographic features, and treatment modalities for those patients with myositis-associated ILD. View this paper
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Articles (288)

  • Article
  • Open Access
1 Citations
3,046 Views
14 Pages

22 July 2024

The loss of vestibular and motor function can occur naturally with aging. Vestibular physiotherapy exercises (VE) specifically address vestibular rehabilitation to reduce imbalances and improve physical condition, like therapeutic exercise (TE). Duri...

  • Review
  • Open Access
1 Citations
4,021 Views
16 Pages

Pediatric Perspectives on Liver Cirrhosis: Unravelling Clinical Patterns and Therapeutic Challenges

  • Lorenza Forna,
  • Laura Bozomitu,
  • Vasile Valeriu Lupu,
  • Ancuta Lupu,
  • Laura Mihaela Trandafir,
  • Anca Adam Raileanu,
  • Camelia Cojocariu,
  • Carmen Anton,
  • Irina Girleanu and
  • Cristina Maria Muzica

22 July 2024

Background: Liver cirrhosis presents significant challenges in the pediatric population due to a complex interplay of etiological factors, clinical manifestations, and limited therapeutic options. The leading contributors to cirrhosis among pediatric...

  • Article
  • Open Access
2 Citations
1,814 Views
11 Pages

Comparative Approaches in Treating Double-J Stent Syndrome: Monotherapy or Combination Therapy?

  • Cătălin Pricop,
  • Carina Alexandra Bandac,
  • Marius Ivanuță,
  • Daniel Rădăvoi,
  • Viorel Jinga and
  • Dragoş Puia

22 July 2024

Introduction: The application of double-J ureteral stents in urology is widespread, but their use is often accompanied by complications and bothersome symptoms, affecting patients’ quality of life (QoL). While various medications have been test...

  • Review
  • Open Access
4 Citations
2,257 Views
14 Pages

Beyond Stress Ischemia: Unveiling the Multifaceted Nature of Coronary Vulnerable Plaques Using Cardiac Computed Tomography

  • Gianluigi Napoli,
  • Saima Mushtaq,
  • Paolo Basile,
  • Maria Cristina Carella,
  • Daniele De Feo,
  • Michele Davide Latorre,
  • Andrea Baggiano,
  • Marco Matteo Ciccone,
  • Gianluca Pontone and
  • Andrea Igoren Guaricci

22 July 2024

Historically, cardiovascular prevention has been predominantly focused on stress-induced ischemia, but recent trials have challenged this paradigm, highlighting the emerging role of vulnerable, non-flow-limiting coronary plaques, leading to a shift t...

  • Article
  • Open Access
1,454 Views
11 Pages

Serotonin-Mediated Anti-Allodynic Effect of Yokukansan on Diabetes-Induced Neuropathic Pain

  • Yoko Kajikawa,
  • Hiroshi Yokomi,
  • Soshi Narasaki,
  • Satoshi Kamiya,
  • Hirotsugu Miyoshi,
  • Takahiro Kato and
  • Yasuo M. Tsutsumi

22 July 2024

Background: Diabetic neuropathic pain is a known complication of diabetes mellitus (DM) and results from the complex interaction of various factors affecting the nervous system. Yokuansan (YKS) is a versatile traditional Japanese herbal medicine with...

  • Article
  • Open Access
6 Citations
2,725 Views
12 Pages

22 July 2024

Background/Objectives: Burning Mouth Syndrome (BMS) patients experience a reduction in health-related quality of life and an increased intake of medication. Photobiomodulation with low-level laser therapy has been demonstrated to be an efficacious tr...

  • Article
  • Open Access
3 Citations
1,986 Views
9 Pages

Early Access for Medicines in ITALY: The Case of Ruxolitinib for Patients with Graft-Versus-Host Disease

  • Lucia Gozzo,
  • Salvatore Leotta,
  • Giovanni Luca Romano,
  • Calogero Vetro,
  • Andrea Duminuco,
  • Giuseppe Milone,
  • Alessandra Cupri,
  • Fanny Erika Palumbo,
  • Serena Brancati and
  • Rosy Ruscica
  • + 8 authors

22 July 2024

After European Medicines Agency (EMA) approval, national pricing and reimbursement procedures are necessary to guarantee access to drugs, based on the willingness to pay and the recognition of therapeutic value. These can result in delays in drug ava...

  • Brief Report
  • Open Access
3 Citations
1,383 Views
7 Pages

22 July 2024

Background: Intrathoracic airway closure frequently occurs during cardiac arrest, possibly impairing ventilation. Previously, capnogram analysis was used to detect this pathophysiological process. In other populations, quasi-static pressure–vol...

  • Article
  • Open Access
1 Citations
2,147 Views
13 Pages

Short- and Long-Term Outcomes in Elderly Patients with Resectable Esophageal Cancer: Upfront Esophagectomy Compared to Surgery after Neoadjuvant Treatments

  • Lucia Moletta,
  • Elisa Sefora Pierobon,
  • Giovanni Capovilla,
  • Irene Sole Zuin,
  • Jose Luis Carrillo Lizarazo,
  • Giulia Nezi,
  • Sara Lonardi,
  • Sabina Murgioni,
  • Sara Galuppo and
  • Gianpietro Zanchettin
  • + 3 authors

22 July 2024

Background/Objectives: Despite the increased incidence of esophageal cancer (EC) in elderly people, there are no clear guidelines for its treatment in these patients. The aim of this study was to compare the outcomes of patients ≥ 75 years with re...

  • Article
  • Open Access
2 Citations
2,468 Views
11 Pages

22 July 2024

Background: The transversus abdominis plane (TAP) block is providing effective postoperative analgesia in patients undergoing cesarean section (CS). This study aims to evaluate and compare the effects on pain levels of bupivacaine alone versus bupiva...

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J. Clin. Med. - ISSN 2077-0383Creative Common CC BY license