Special Issue "Challenges in Abdominal Aortic Aneurysm"

Dear Colleagues,

An abdominal aortic aneurysm (AAA) is a chronic inflammatory, multifactorial disease, more prevalent in men >65 years. AAA risk factors include smoking, male sex and positive family history, and AAAs are most common in men of >65 years of age. Infrarenal AAAs are the most frequently observed type, and less common types involve renal arteries (pararenal AAAs) and infrarenal segments closely approaching renal arteries, without involving them (juxtarenal AAAs). These types of AAAs, together with suprarenal AAAs, pose particular technical challenges in endovascular repair due to their complex anatomy.

Other challenges are related to the management of AAA patients with concomitant diseases. Cancer is one of these comorbidities, and in retrospective studies, the concomitant presence of an AAA and cancer has been estimated to be 4%-38%.

AAAs are typically asymptomatic until rupture, an event with a 65-85% mortality rate. The most recognized predictor of rupture is size, but a significant number of smaller aneurysms also rupture.

The present Special Issue aims to highlight challenges in AAAs; therefore, we invite authors to propose articles related to the choice of strategy for the prevention of aneurysm rupture; methods for the identification of aneurysms carrying a high risk of rupture even though they have a diameter below the surgical threshold; or studies focused on methods for the prediction of AAA patients’ outcomes or for the identification of patients at risk of endoleaks.

Prof. Dr. Natzi Sakalihasan
Dr. Lucia Musumeci
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• rupture of abdominal aortic aneurysms;
• EVAR;
• FEVAR;
• BEVAR;
• biomechanical analysis;
• endoleaks;
• cancer