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Journal of Clinical Medicine, Volume 12, Issue 9

May-1 2023 - 303 articles

Cover Story: Head and neck (HN) squamous cell carcinomas (SCCs) originate from the epithelial cells of the mucosal linings of the upper aerodigestive tract, which includes the oral cavity, the pharynx, the larynx, and the sinonasal cavities. Human papilloma virus (HPV) is another independent risk factor for oropharyngeal SCC, but it is only a minor contributor to oral cavity SCC (OSCC). Betel quid chewing is also an established risk factor in southeast Asian countries. However, OSCC, and especially oral tongue cancer, incidence has been reported to be increasing in several countries, suggesting risk factors that have not been identified yet. This review summarizes the established risk factors for oral cavity squamous cell carcinomas and examines other undemonstrated risk factors for HNSCC. View this paper
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Articles (303)

  • Article
  • Open Access
1 Citations
2,091 Views
9 Pages

Association of the Calcification Score of the Abdominal Aorta, Common Iliac, and Renal Arteries with Outcomes in Living Kidney Donors

  • Luís Costa Ribeiro,
  • Manuela Almeida,
  • Jorge Malheiro,
  • Filipa Silva,
  • Diogo Nunes-Carneiro,
  • La Salete Martins,
  • Sofia Pedroso and
  • Miguel Silva-Ramos

Background: Vascular calcification is an ever-more-common finding in protocoled pre-transplant imaging in living kidney donors. We intended to explore whether a connection could be found between the Agatston calcification score, prior to kidney donat...

  • Brief Report
  • Open Access
3 Citations
1,979 Views
9 Pages

A Trend towards Diaphragmatic Muscle Waste after Invasive Mechanical Ventilation in Multiple Trauma Patients—What to Expect?

  • Liliana Mirea,
  • Cristian Cobilinschi,
  • Raluca Ungureanu,
  • Ana-Maria Cotae,
  • Raluca Darie,
  • Radu Tincu,
  • Oana Avram,
  • Sorin Constantinescu,
  • Costin Minoiu and
  • Alexandru Baetu
  • + 1 author

Considering the prioritization of life-threatening injuries in trauma care, secondary dysfunctions such as ventilator-induced diaphragmatic dysfunction (VIDD) are often overlooked. VIDD is an entity induced by muscle inactivity during invasive mechan...

  • Review
  • Open Access
16 Citations
5,997 Views
19 Pages

Utility of MRI in Quantifying Tissue Injury in Cervical Spondylotic Myelopathy

  • Ali Fahim Khan,
  • Grace Haynes,
  • Esmaeil Mohammadi,
  • Fauziyya Muhammad,
  • Sanaa Hameed and
  • Zachary A. Smith

Cervical spondylotic myelopathy (CSM) is a progressive disease that worsens over time if untreated. However, the rate of progression can vary among individuals and may be influenced by various factors, such as the age of the patients, underlying cond...

  • Article
  • Open Access
26 Citations
4,631 Views
11 Pages

Smoking Increases the Risk of Hepatocellular Carcinoma and Cardiovascular Disease in Patients with Metabolic-Associated Fatty Liver Disease

  • Jeong-Ju Yoo,
  • Man Young Park,
  • Eun Ju Cho,
  • Su Jong Yu,
  • Sang Gyune Kim,
  • Yoon Jun Kim,
  • Young Seok Kim and
  • Jung-Hwan Yoon

The association of smoking with hepatocellular carcinoma (HCC) or cardiovascular disease (CVD) has been reported, but the study of its relationship with metabolic-associated fatty liver disease (MAFLD) is limited. We aimed to investigate the effect o...

  • Article
  • Open Access
3 Citations
4,013 Views
10 Pages

The Liver Can Deliver: Utility of Hepatic Function Tests as Predictors of Outcome in COVID-19, Influenza and RSV Infections

  • Einat Ritter,
  • Eden Shusterman,
  • Lior Prozan,
  • Orli Kehat,
  • Ahuva Weiss Meilik,
  • Oren Shibolet and
  • Jacob Nadav Ablin

Background: liver test abnormalities have been described in patients with Coronavirus-2019 (COVID-19), and hepatic involvement may correlate with disease severity. With the relaxing of COVID-19 restrictions, seasonal respiratory viruses now circulate...

  • Article
  • Open Access
2 Citations
3,323 Views
13 Pages

Efficacy and Safety of Chemotherapy in Elderly Patients with Unresectable Pancreatic Cancer

  • Byung Soo Kwan,
  • Ok Jae Lee,
  • Hyun Jin Kim,
  • Kwang Min Kim,
  • Sang Goon Shim,
  • Dae Hyeon Cho,
  • Sung Min Kong,
  • Jun Young Kim and
  • Jun Ho Ji

Background/Aims: The incidence of pancreatic cancer (PC) is gradually increasing among elderly individuals, but there are insufficient clinical data on elderly individuals. To determine the efficacy and safety of chemotherapy, we compared the. the ou...

  • Article
  • Open Access
4 Citations
2,597 Views
11 Pages

Quantitative Assessment of Upper Limb Movement in Post-Stroke Adults for Identification of Sensitive Measures in Reaching and Lifting Activities

  • Monika Błaszczyszyn,
  • Agnieszka Szczęsna,
  • Mariusz Konieczny,
  • Paweł Pakosz,
  • Stefan Balko and
  • Zbigniew Borysiuk

Background: The assumption of this work is the achievement of objective results of the movement structure, which forms the basis for in-depth analysis and, consequently, for determining the upper limb movements that are most affected by stroke compar...

  • Article
  • Open Access
18 Citations
3,169 Views
11 Pages

The Presence of Myosteatosis Is Associated with Age, Severity of Liver Disease and Poor Outcome and May Represent a Prodromal Phase of Sarcopenia in Patients with Liver Cirrhosis

  • Eleni Geladari,
  • Theodoros Alexopoulos,
  • Meropi D. Kontogianni,
  • Larisa Vasilieva,
  • Iliana Mani,
  • Roxane Tenta,
  • Vasilios Sevastianos,
  • Ioannis Vlachogiannakos and
  • Alexandra Alexopoulou

Background/Aims: Myosteatosis implies impaired muscle quality. The aim of the study was to investigate the association of myosteatosis with other muscle abnormalities and its role in the prognosis of liver cirrhosis (LC). Method: Skeletal muscle inde...

  • Article
  • Open Access
8 Citations
3,756 Views
11 Pages

The potential effects of asymptomatic flexible flatfoot (FF) on children’s health-related quality of life (QoL) and objective clinical foot characteristics have been poorly investigated in the literature. Therefore, this study aimed to analyse...

  • Article
  • Open Access
2,052 Views
11 Pages

Value of Fractional Exhaled Nitric Oxide in Diagnosing Mild Asthma Responsive to Inhaled Corticosteroids

  • Natasa Karamarkovic Lazarusic,
  • Eugenija Kasap Basioli,
  • Ena Tolic,
  • Martina Dokoza and
  • Gordana Pavlisa

Background: Mild asthma is often characterized by normal spirometric values and a negative bronchodilation test (BDT), which makes accurate diagnosis challenging. The aim of our study was to evaluate the diagnostic accuracy of fractional exhaled nitr...

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J. Clin. Med. - ISSN 2077-0383