- Article
Development of a Single-Step Antibody–Drug Conjugate Purification Process with Membrane Chromatography
- Juan Carlos Cordova,
- Sheng Sun,
- Jeffrey Bos,
- Srinath Thirumalairajan,
- Sanjeevani Ghone,
- Miyako Hirai,
- Ricarda A. Busse,
- Julia S. v. der Hardt,
- Ian Schwartz and
- Jieyu Zhou
Membrane chromatography is routinely used to remove host cell proteins, viral particles, and aggregates during antibody downstream processing. The application of membrane chromatography to the field of antibody-drug conjugates (ADCs) has been applied...

