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Vaccines, Volume 2, Issue 1

March 2014 - 12 articles

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Articles (12)

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Article

13 Citations

7,050 Views

13 Pages

Pilot Study on the Use of DNA Priming Immunization to Enhance Y. pestis LcrV-Specific B Cell Responses Elicited by a Recombinant LcrV Protein Vaccine

Wei Li,
Shixia Wang and
Shan Lu

Vaccines2014, 2(1), 36-48;https://doi.org/10.3390/vaccines2010036

27 December 2013

Recent studies indicate that DNA immunization is powerful in eliciting antigen-specific antibody responses in both animal and human studies. However, there is limited information on the mechanism of this effect. In particular, it is not known whethe...

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Review

21 Citations

7,093 Views

14 Pages

Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies

Garnett Kelsoe,
Laurent Verkoczy and
Barton F. Haynes

Vaccines2014, 2(1), 1-14;https://doi.org/10.3390/vaccines2010001

19 December 2013

In this brief review, we discuss immune tolerance as a factor that determines the magnitude and quality of serum antibody responses to HIV-1 infection and vaccination in the context of recent work. We propose that many conserved, neutralizing epitope...

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Vaccines - ISSN 2076-393X

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