You are currently viewing a new version of our website. To view the old version click .

Antioxidants, Volume 14, Issue 1

January 2025 - 119 articles

Cover Story: Hydroxyl radicals are the most reactive oxidants among reactive oxygen species and a major cause of oxidative damage to biomolecules in several subcellular components. The excessive production of hydroxyl radicals is linked to diseases such as cancer and neurodegenerative disorders. Rapid and reliable detection of hydroxyl radicals near DNA and within subcellular organelles is important. However, the high reactivity and short half-lives of hydroxyl radicals result in exceptionally low concentrations, which pose significant challenges to their detection. This review highlights advances in fluorescent probes for the detection of hydroxyl radicals in distinct subcellular regions with an emphasis on the probe design, applications, and limitations, and it outlines pathways to enhance future development. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (119)

  • Review
  • Open Access
7 Citations
4,259 Views
36 Pages

Treating Metabolic Dysregulation and Senescence by Caloric Restriction: Killing Two Birds with One Stone?

  • Lara Russo,
  • Serena Babboni,
  • Maria Grazia Andreassi,
  • Jalil Daher,
  • Paola Canale,
  • Serena Del Turco and
  • Giuseppina Basta

16 January 2025

Cellular senescence is a state of permanent cell cycle arrest accompanied by metabolic activity and characteristic phenotypic changes. This process is crucial for developing age-related diseases, where excessive calorie intake accelerates metabolic d...

  • Article
  • Open Access
8 Citations
2,842 Views
52 Pages

Enhancement of Cognitive Benefits and Anti-Anxiety Effects of Phytolacca americana Fruits in a Zebrafish (Danio rerio) Model of Scopolamine-Induced Memory Impairment

  • Lucia-Florina Popovici,
  • Ion Brinza,
  • Florentina Gatea,
  • Georgiana Ileana Badea,
  • Emanuel Vamanu,
  • Simona Oancea and
  • Lucian Hritcu

15 January 2025

Phytolacca americana fruits exhibit a wide range of biological activities, including antimicrobial, anti-inflammatory, and anticancer properties. This study aims to investigate the phenolic profile of hydroethanolic extracts from both fresh (PEC) and...

  • Article
  • Open Access
1 Citations
2,110 Views
25 Pages

Ferroptosis Transcriptional Regulation and Prognostic Impact in Medulloblastoma Subtypes Revealed by RNA-Seq

  • Christophe Desterke,
  • Yuanji Fu,
  • Jenny Bonifacio-Mundaca,
  • Claudia Monge,
  • Pascal Pineau,
  • Jorge Mata-Garrido and
  • Raquel Francés

15 January 2025

Medulloblastoma (MB) is the most common malignant brain tumor in children, typically arising during infancy and childhood. Despite multimodal therapies achieving a response rate of 70% in children older than 3 years, treatment remains challenging. Fe...

  • Review
  • Open Access
4 Citations
4,515 Views
22 Pages

15 January 2025

Acute pancreatitis (AP) is a potentially fatal acute digestive disease that is widespread globally. Although significant progress has been made in the previous decade, the study of mechanisms and therapeutic strategies is still far from being complet...

  • Article
  • Open Access
1 Citations
1,824 Views
18 Pages

DNA Methylation and Transcriptome Profiling Reveal the Role of the Antioxidant Pathway and Lipid Metabolism in Plectropomus leopardus Skin Color Formation

  • Yang Liu,
  • Linna Wang,
  • Zhentong Li,
  • Linlin Li,
  • Tangtang Ding,
  • Shuai Chen,
  • Pengfei Duan,
  • Xinyi Wang,
  • Yishu Qiu and
  • Xiaoyu Ding
  • + 1 author

15 January 2025

Leopard coral grouper (Plectropomus leopardus), possessing a distinct red body color, is an important species in commercial markets; however, the high ratio of black individuals under intensive cultivation has limited the commercial value of the spec...

  • Review
  • Open Access
16 Citations
4,157 Views
20 Pages

15 January 2025

Normal tissues typically maintain partial oxygen pressure within a range of 3–10% oxygen, ensuring homeostasis through a well-regulated oxygen supply and responsive vascular network. However, in solid tumors, rapid growth often outpaces angioge...

  • Article
  • Open Access
1,494 Views
14 Pages

15 January 2025

Diabetic retinopathy is characterized by hyperglycemic retinal pigment epithelial cells that secrete excessive pro-inflammatory cytokines and VEGF, leading to retinal damage and vision loss. Cobalt protoporphyrin (CoPP) is a compound that can reduce...

  • Article
  • Open Access
6 Citations
1,869 Views
20 Pages

Structure–Antioxidant Activity Relationship of Polysaccharides Isolated by Microwave/Ultrasonic-Assisted Extraction from Pleurotus ferulae

  • Hongjin Zhou,
  • Zhongxiong Fan,
  • Yuan Li,
  • Xuelian Liu,
  • Bo Wang,
  • Jianguo Xing,
  • Jiang He,
  • Ruifang Zheng and
  • Jinyao Li

14 January 2025

To investigate the structure–antioxidant activity relationship, Pleurotus ferulae polysaccharides were extracted using ultrasonic (U-PFPS) and microwave/ultrasonic-assisted methods (MU-PFPS). Compared to U-PFPS with a molecular weight of 1.566...

  • Article
  • Open Access
2 Citations
1,807 Views
17 Pages

Shrimp White Spot Viral Infections Are Attenuated by Organic Acids by Regulating the Expression of HO-1 Oxygenase and β-1,3-Glucan-Binding Protein

  • Ioan Pet,
  • Igori Balta,
  • Nicolae Corcionivoschi,
  • Tiberiu Iancu,
  • Ducu Stef,
  • Lavinia Stef and
  • Iuliana Cretescu

14 January 2025

The absence of efficient on-farm interventions against white spot syndrome viral (WSSV) infections can cause significant economic losses to shrimp farmers. With this exploratory study we aimed to test, both in vitro and in vivo, the efficacy of an or...

of 12

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Antioxidants - ISSN 2076-3921