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Antioxidants, Volume 13, Issue 9

September 2024 - 126 articles

Cover Story: Frontotemporal dementia (FTD) causes progressive neurodegeneration in the frontal and temporal lobes, impairing behavior, cognition, and language. With no effective treatment, new therapies are crucial. Dimethyl fumarate (DMF), an NRF2 activator, has shown neuroprotective, antioxidant, and anti-inflammatory effects in TAU-dependent FTD mice. This study tested DMF in TDP-43-related FTD mice with early cognitive impairment. The mice received oral DMF from the presymptomatic to symptomatic stages. Cognitive improvement was observed by postnatal day 60 and continued to increase at day 90. This correlated with the neuroprotection and reduced astrogliosis demonstrated in the dentate gyrus and prefrontal cortex. The results suggest DMF's potential for treating TDP-43-dependent FTD. View this paper
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Articles (126)

  • Article
  • Open Access
3 Citations
3,028 Views
16 Pages

23 September 2024

Lactobacillus delbrueckii subsp. bulgaricus (L. bulgaricus) is one of the most commonly employed Lactobacillus in the food industry. Exopolysaccharides (EPS) of Lactobacillus, which are known to exhibit probiotic properties, are secondary metabolites...

  • Article
  • Open Access
23 Citations
2,937 Views
23 Pages

23 September 2024

Citrus species are widely cultivated across the globe and frequently encounter drought stress during their growth and development phases. Previous research has indicated that citrus species synthesize flavonoids as a response mechanism to drought str...

  • Article
  • Open Access
4 Citations
2,403 Views
23 Pages

Synthesis, Characterization and Assessment of Antioxidant and Melanogenic Inhibitory Properties of Edaravone Derivatives

  • R. Divya Mohan,
  • S. A. Anaswara,
  • Naveen V. Kulkarni,
  • Dimitar G. Bojilov,
  • Stanimir P. Manolov,
  • Iliyan I. Ivanov,
  • Jamelah S. Al-Otaibi and
  • Y. Sheena Mary

23 September 2024

A series of edaravone derivatives and the corresponding Cu(II) complexes were synthesized and characterized using spectroscopic and analytical techniques such as IR, UV, NMR and elemental analysis. Antioxidant activities of all compounds were examine...

  • Article
  • Open Access
1 Citations
2,994 Views
18 Pages

8-Week Kaempferia parviflora Extract Administration Improves Submaximal Exercise Capacity in Mice by Enhancing Skeletal Muscle Antioxidant Gene Expression and Plasma Antioxidant Capacity

  • Jiapeng Huang,
  • Yishan Tong,
  • Shuo Wang,
  • Takashi Tagawa,
  • Yasuhiro Seki,
  • Sihui Ma,
  • Ziwei Zhang,
  • Tiehan Cao,
  • Haruki Kobori and
  • Katsuhiko Suzuki

23 September 2024

Black ginger (Kaempferia parviflora) extract (KPE) is extracted from a ginger family plant grown in Thailand. The polyphenolic components have potential antioxidant effects and have been reported to enhance exercise performance. However, the impact o...

  • Article
  • Open Access
2 Citations
2,198 Views
16 Pages

Propylene Glycol Alleviates Oxidative Stress and Enhances Immunity in Ketotic Cows through Modulating Amino Acid and Lipid Metabolism

  • Jian Tan,
  • Huiying Zhao,
  • Liuxue Li,
  • Ying Wang,
  • Yucong Pan,
  • Luoyun Fang,
  • Yuchao Zhao and
  • Linshu Jiang

23 September 2024

This study investigates the impact of propylene glycol (PRG) on ketotic cows, focusing on alleviating oxidative stress and enhancing immunity through modulating amino acid and lipid metabolism. Ketosis, a prevalent metabolic disease in dairy cows, ne...

  • Article
  • Open Access
2 Citations
2,199 Views
19 Pages

Oxidative Stability of Fish Oil-Loaded Nanocapsules Produced by Electrospraying Using Kafirin or Zein Proteins as Wall Materials

  • Nor E. Rahmani-Manglano,
  • Elnaz Z. Fallahasghari,
  • Ana C. Mendes,
  • Mogens L. Andersen,
  • Emilia M. Guadix,
  • Ioannis S. Chronakis and
  • Pedro J. García-Moreno

23 September 2024

The encapsulation of fish oil by monoaxial electrospraying using kafirin or zein proteins as hydrophobic wall materials was investigated. Kafirin resulted in spherical fish oil-loaded nanocapsules (>50% of capsules below 1 µm), whereas zein...

  • Article
  • Open Access
4 Citations
2,176 Views
15 Pages

Melatonin Enhances Heat Tolerance via Increasing Antioxidant Enzyme Activities and Osmotic Regulatory Substances by Upregulating zmeno1 Expression in Maize (Zea mays L.)

  • Liru Cao,
  • Abbas Muhammad Fahim,
  • Xiaohan Liang,
  • Senmiao Fan,
  • Yinghui Song,
  • Huafeng Liu,
  • Feiyu Ye,
  • Chenchen Ma,
  • Dongling Zhang and
  • Xiaomin Lu

22 September 2024

Heat stress severely affects the yield and quality of maize. Melatonin (N-acetyl-5-methoxy-tryptamin, MT) plays an important role in various types of stress resistance in plants, including heat tolerance. Enolase (ENO, 2-phospho-D-glycerate hydrolyas...

  • Review
  • Open Access
44 Citations
10,608 Views
37 Pages

Anti-Inflammatory and Anticancer Effects of Anthocyanins in In Vitro and In Vivo Studies

  • Tomasz Kowalczyk,
  • Martyna Muskała,
  • Anna Merecz-Sadowska,
  • Joanna Sikora,
  • Laurent Picot and
  • Przemysław Sitarek

22 September 2024

Anthocyanins, a class of flavonoid compounds responsible for the vibrant colors of many fruits and vegetables, have received considerable attention in recent years due to their potential health benefits. This review, focusing on evidence from both in...

  • Review
  • Open Access
12 Citations
5,503 Views
16 Pages

Recent Advances in the Extraction and Characterization of Bioactive Compounds from Corn By-Products

  • Ulises Ramírez-Esparza,
  • María Cristina Agustín-Chávez,
  • Emilio Ochoa-Reyes,
  • Sandra M. Alvarado-González,
  • Leticia X. López-Martínez,
  • Juan A. Ascacio-Valdés,
  • Guillermo C. G. Martínez-Ávila,
  • Lilia Arely Prado-Barragán and
  • José Juan Buenrostro-Figueroa

21 September 2024

Maize comes in a variety of colors, including white, yellow, red, blue, and purple, which is due to the presence of phytochemicals such as carotenoids, anthocyanins, flavonoids, phytosterols, and some hydroxycinnamic acid derivatives. In Mexico, maiz...

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Antioxidants - ISSN 2076-3921Creative Common CC BY license