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Antioxidants, Volume 13, Issue 7

July 2024 - 130 articles

Cover Story: Aquafeed contamination caused by microplastics (MPs) poses a risk to fish health due to their gastrointestinal absorption and translocation to other organs, particularly the liver, triggering oxidative stress. The present study aimed to combine the use of natural astaxanthin contained in natural-based microcapsules to counteract the negative side effects of MPs in juvenile European seabass (Dicentrarchus labrax) fed diets containing MPs. Specifically, starch contained in the microcapsules enabled the coagulation of MPs in fish gut, limiting their absorption and accumulation in all the tissues analyzed. Conversely, natural astaxanthin led to the mitigation of oxidative stress. This technology represents a new and economically affordable approach to promote fish welfare and quality within the aquaculture sector. View this paper
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Articles (130)

  • Article
  • Open Access
4 Citations
2,340 Views
20 Pages

Spotlight on Secondary Metabolites Produced by an Early-Flowering Apulian Artichoke Ecotype Sanitized from Virus Infection by Meristem-Tip-Culture and Thermotherapy

  • Roberta Spanò,
  • Patrizia Gena,
  • Vito Linsalata,
  • Valeria Sini,
  • Isabella D’Antuono,
  • Angela Cardinali,
  • Pietro Cotugno,
  • Giuseppe Calamita and
  • Tiziana Mascia

Globe artichoke (Cynara cardunculus L. subsp. scolymus) is an important crop of the Mediterranean basin characterized by many properties, like hepatoprotective, anticarcinogenic, antioxidant, antibacterial, and beneficial to human health. The high bi...

  • Article
  • Open Access
5 Citations
3,469 Views
23 Pages

The booming aquaculture industry has created a strong demand for fishmeal and increased environmental pressures. Spirulina, as a potential alternative to fishmeal, has been shown to have growth-promoting and animal health-enhancing properties. In thi...

  • Article
  • Open Access
5 Citations
2,765 Views
18 Pages

Novel Inhibitor of Keap1-Nrf2 Protein–Protein Interaction Attenuates Osteoclastogenesis In Vitro and Prevents OVX-Induced Bone Loss In Vivo

  • Zhihao Chen,
  • Hongyuan Yao,
  • Alessandra Marie Encarnacion,
  • Jujin Jeong,
  • Yunju Choi,
  • Sangwook Park,
  • Sunwoo Lee and
  • Taehoon Lee

Keap1 interacts with Nrf2 by assisting in its ubiquitination and subsequent proteolysis. By preventing ROS accumulation during RANKL-induced osteoclastogenesis, Nrf2 activation can prevent the differentiation of osteoclasts. Additionally, inhibiting...

  • Article
  • Open Access
8 Citations
2,393 Views
19 Pages

Cyprinus carpio is a significant freshwater species with substantial nutritional and economic value. Rice–carp co-culture represents one of its principal cultivation methods. However, in the system, the optimal farming density for carp and the...

  • Review
  • Open Access
19 Citations
7,008 Views
23 Pages

The Role of Oxidative Stress in Hypertension: The Insight into Antihypertensive Properties of Vitamins A, C and E

  • Ewelina Młynarska,
  • Laura Biskup,
  • Maria Możdżan,
  • Olivia Grygorcewicz,
  • Zofia Możdżan,
  • Jan Semeradt,
  • Michał Uramowski,
  • Jacek Rysz and
  • Beata Franczyk

Hypertension stands as a pervasive global health challenge, contributing significantly to mortality rates worldwide. Various factors, including lifestyle choices and dietary habits, contribute to the development of hypertension. In recent years, oxid...

  • Article
  • Open Access
1 Citations
2,205 Views
23 Pages

Anthocyanin-Rich Berry Extracts Affect SN-38-Induced Response: A Comparison of Non-Tumorigenic HCEC-1CT and HCT116 Colon Carcinoma Cells

  • Cornelia Schmutz,
  • Crepelle Plaza,
  • Franziska Steiger,
  • Natascha Stoirer,
  • Judith Gufler,
  • Gudrun Pahlke,
  • Frank Will,
  • Walter Berger and
  • Doris Marko

Chemotherapy with irinotecan (CPT-11), the pro-drug of the highly cytotoxic SN-38, is among the standard-of-care treatments for colorectal cancer. To counteract undesired toxic side effects on healthy tissue such as the intestinal epithelium, the use...

  • Article
  • Open Access
6 Citations
3,731 Views
16 Pages

A 70-day feeding experiment was performed to investigate the effects of dietary vitamin E at different addition levels (0, 100, 200, and 400 mg/kg) on the growth, collagen content, antioxidant capacity, and expressions of genes related to the transfo...

  • Article
  • Open Access
5 Citations
2,055 Views
17 Pages

Optimization of Oil and Tocopherol Extraction from Maqui (Aristotelia chilensis (Mol.) Stuntz) by Supercritical CO2 Procedure

  • Camila Sánchez,
  • Alicia Rodríguez,
  • Francisca Reinoso,
  • Gretel Dovale-Rosabal,
  • Nalda Romero,
  • Alejandra Espinosa,
  • María Elsa Pando,
  • Benjamín Claria,
  • Rodrigo Valenzuela and
  • Cielo Char
  • + 1 author

This study focused on the oil extraction from freeze-dried maqui (Aristotelia chilensis) by supercritical fluid extraction with carbon dioxide (SFE-CO2). The basic objective was to optimize the oil yield and the tocopherol concentration. A Box/Behnke...

  • Article
  • Open Access
3 Citations
2,293 Views
20 Pages

This study investigated the safety and functionality of traditional African sourdough flatbread (kisra), based on the content of biogenic amines (BAs) and antioxidant compounds and their improvement using lactic acid bacteria (LAB) species. The prima...

  • Article
  • Open Access
3 Citations
1,660 Views
16 Pages

Study on a Mechanism of Improving MaAPX1 Protein Activity by Mutating Methionine to Lysine

  • Lu Xiao,
  • Guoxiang Jiang,
  • Hongmei Lai,
  • Xiaoyan Duan,
  • Huiling Yan,
  • Shaoge Chen,
  • Zexin Chen and
  • Xuewu Duan

Ascorbate peroxidases (APXs) are key components of the ascorbate–glytathione cycle, which plays an important role in removing excess reactive oxygen species (ROS) in plants. Herein, MaAPX1 was verified as being involved in the ripening and sene...

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Antioxidants - ISSN 2076-3921