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Antioxidants, Volume 13, Issue 3

2024 March - 130 articles

Cover Story: Melanocyte death due to oxidative stress and autoimmune reactions causes hypopigmentation, such as vitiligo. Melanin overproduction from melanocytes stimulated by oxidative stress, hormones, or substrates causes hyperpigmentation, such as melasma. Thus, we hypothesized that certain antioxidants may help alleviate skin pigmentation disorders. This study highlights the multifaceted effects of L-cysteine, L-ascorbic acid (vitamin C), and their derivatives on melanocyte viability and melanin levels under several experimental conditions, which can guide the therapeutic application of each compound. In particular, it suggests that L-cysteine, L-cysteinamide, or L-ascorbic acid may be applied to prevent and treat skin hypopigmentation, hyperpigmentation, or both diseases in the matched order. View this paper
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Articles (130)

  • Article
  • Open Access
1 Citations
2,654 Views
15 Pages

Syrah Grape Polyphenol Extracts Protect Human Skeletal Muscle Cells from Oxidative and Metabolic Stress Induced by Excess of Palmitic Acid: Effect of Skin/Seed Ripening Stage

  • Adriana Capozzi,
  • Auriane Dudoit,
  • Luca Garcia,
  • Gilles Carnac,
  • Gérald Hugon,
  • Cédric Saucier,
  • Catherine Bisbal and
  • Karen Lambert

Metabolic skeletal muscle (SM) dysfunction, triggered by increased oxidative stress and mitochondrial impairment, is a pivotal contributor to obesity-associated insulin resistance (IR). Addressing obesity and SM IR demands substantial lifestyle chang...

  • Article
  • Open Access
3 Citations
3,343 Views
15 Pages

Phenolic Compounds in Berries of Winter-Resistant Actinidia arguta Miq. and Actinidia kolomikta Maxim.: Evidence of Antioxidative Activity

  • Laima Česonienė,
  • Viktorija Januškevičė,
  • Sandra Saunoriūtė,
  • Mindaugas Liaudanskas,
  • Vaidotas Žvikas,
  • Ričardas Krikštolaitis,
  • Pranas Viškelis,
  • Dalia Urbonavičienė,
  • Paulina Martusevičė and
  • Jonas Viškelis
  • + 3 authors

Variations between fruit cultivars can significantly impact their biochemical composition. The present research examined the variability in the qualitative and quantitative content of phenolic compounds in berry extracts of Actinidia kolomikta and Ac...

  • Article
  • Open Access
11 Citations
9,094 Views
21 Pages

The Cerebral Protective Effect of Novel Erinacines from Hericium erinaceus Mycelium on In Vivo Mild Traumatic Brain Injury Animal Model and Primary Mixed Glial Cells via Nrf2-Dependent Pathways

  • Kam-Fai Lee,
  • Yung-Yu Hsieh,
  • Shui-Yi Tung,
  • Chih-Chuan Teng,
  • Kung-Chuan Cheng,
  • Meng-Chiao Hsieh,
  • Cheng-Yi Huang,
  • Ko-Chao Lee,
  • Li-Ya Lee and
  • Hsing-Chun Kuo
  • + 2 authors

Hericium erinaceus, a consumable mushroom, has shown a potential to enhance the production of neuroprotective bioactive metabolites. Traumatic brain injury (TBI) often leads to cognitive, physical, and psychosocial impairments, resulting in neuroinfl...

  • Article
  • Open Access
27 Citations
2,645 Views
19 Pages

Se Alleviated Pb-Caused Neurotoxicity in Chickens: SPS2-GPx1-GSH-IL-2/IL-17-NO Pathway, Selenoprotein Suppression, Oxidative Stress, and Inflammatory Injury

  • Yansheng Li,
  • Jiatian Liang,
  • Chunyu Jiang,
  • Jiawen Cui,
  • Lan Hong,
  • Zhiyu Hao,
  • You Tang,
  • Yuhao Liu,
  • Xun Cui and
  • Xiaohua Teng

Lead (Pb), a heavy metal environmental pollutant, poses a threat to the health of humans and birds. Inflammation is one of the most common pathological phenomena in the case of illness and poisoning. However, the underlying mechanisms of inflammation...

  • Article
  • Open Access
3 Citations
2,714 Views
23 Pages

Effect of Gracilaria vermiculophylla Macroalga on Non-Alcoholic Fatty Liver Disease in Obese Rats

  • Maitane González-Arceo,
  • Leixuri Aguirre,
  • María Teresa Macarulla,
  • Clàudia Gil-Pitarch,
  • María Luz Martínez-Chantar,
  • María P. Portillo and
  • Saioa Gómez-Zorita

Marine algae are valuable sources of bioactive compounds that have the potential to be used in the management of various pathologies. Despite the increasing prevalence of NAFLD, the absence of an approved effective pharmacological treatment with demo...

  • Article
  • Open Access
19 Citations
5,670 Views
27 Pages

The study aimed to optimize hydrolysis conditions and isolate and identify bioactive peptides with anti-skin aging effects from Acheta domesticus (house cricket). A. domesticus proteins underwent hydrolysis using Alcalase® and optimized condition...

  • Article
  • Open Access
7 Citations
2,790 Views
13 Pages

TNFRSF1B Signaling Blockade Protects Airway Epithelial Cells from Oxidative Stress

  • Javier Checa,
  • Pau Fiol,
  • Marta Guevara and
  • Josep M. Aran

Progressive respiratory airway destruction due to unresolved inflammation induced by periodic infectious exacerbation episodes is a hallmark of cystic fibrosis (CF) lung pathology. To clear bacteria, neutrophils release high amounts of reactive oxyge...

  • Article
  • Open Access
6 Citations
2,239 Views
15 Pages

This study investigated the effects of dietary chitosan oligosaccharide (COS) supplementation on meat quality, antioxidant capacity, and muscle fiber characteristics in the thigh muscle of broilers. The results showed that dietary COS supplementation...

  • Article
  • Open Access
9 Citations
3,228 Views
16 Pages

Mealworm, migratory locust, and house cricket have recently been recognized by the European Commission as novel foods, thus being suitable in different food applications. In this work, we tested their powders as meat extenders at 5% (w/w) inclusion i...

  • Article
  • Open Access
1 Citations
3,076 Views
17 Pages

The Oxidative Stability of Champagne Base Wines Aged on Lees in Barrels: A 2-Year Study

  • Charlotte Maxe,
  • Rémy Romanet,
  • Michel Parisot,
  • Régis D. Gougeon and
  • Maria Nikolantonaki

In contrast with the elaboration of still wines, the impact of barrel aging before the “prise de mousse” on the aging potential of Champagne base wines has not been studied so far. In the present study, the oxidative stability and related...

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Antioxidants - ISSN 2076-3921