Antioxidants, Volume 10, Issue 12
December 2021 - 175 articles
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Cover Story: Glutathione plays a key role in maintaining a physiological balance between prooxidants and antioxidants in the human body. This work presents the influence of maternal smoking as a source of oxidative stress measured by total oxidant capacity (TOC) on reduced glutathione (GSH), oxidized glutathione (GSSG), glutathione peroxidase (GPx-3), and reductase (GR) amount in maternal and umbilical cord blood. We found that oxidative stress generated by the toxic compounds in cigarette smoke impairs the homeostasis of glutathione in both mother and newborn. A twice lower value of the cell’s redox status index expressed by the GSH/GSSG ratio in neonates of smoking mothers compared to the non-smoking group may confirm the negative influence of maternal smoking on the oxidative–antioxidant balance in newborns. View this paper 
