Oxidative Stress in Neurodegeneration and Neuroinflammation

Dear Colleagues,

Oxidative stress, neurodegeneration and neuroinflammation are interrelated factors in the aetiology of several brain and retinal degenerative disorders, such as Alzheimer’s and Parkinson´s disease, retinitis pigmentosa, age-related macular degeneration and glaucoma. Oxidative stress results from the imbalance between the production and consumption of reactive oxygen species (ROS). This shift in redox homeostasis can initiate the synthesis and release of pro-inflammatory mediators and the infiltration of immune cells that can further potentiate oxidative stress. These cyclical processes, when uncontrolled, contribute to neuronal cell loss and severe tissue damage.

We invite you to submit your latest research findings or a review article to this Special Issue, “Oxidative Stress in Neurodegeneration and Neuroinflammation”. We aim to gather the latest research about the role of oxidative stress in neurodegeneration and neuroinflammation. We welcome submissions concerning all research models (e.g., in vitro, iPSC-derived cells, organoids, animal models), focusing on all the different nervous system tissues and cell types (e.g., retina, brain, spinal cord, neurons, microglia, astrocytes) and using all types of molecular and cellular approaches that contribute to unraveling and clarifying the pathophysiology and the molecular mechanisms related to neurodegenerative disorders.

We look forward to your contribution.

Dr. C. Henrique Alves
Dr. Peter M.J. Quinn
Dr. António Francisco Ambrósio

Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.