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Brain Sciences, Volume 12, Issue 7

July 2022 - 148 articles

Cover Story: Various scales allow for collecting Patient-Reported Outcomes (PROs). Their use should be expanded, moving from prescriptive to circular clinical interactions. Patients with nonaffective and affective psychoses suffer from distressing symptoms that are commonly treated with antipsychotics. These drugs are effective, but because of their side effects they also compromise patients’ quality of life and functioning. This burden should be recognized and clinicians should take care of it to increase overall patient well-being. Among PROs, the Glasgow Antipsychotic Side-Effect Scale has been indicated as a practical tool for collecting antipsychotics’ side effects. Our goal was to offer our Italian-speaking patients the opportunity to use such an instrument. View this paper
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Articles (148)

  • Case Report
  • Open Access
2 Citations
2,467 Views
13 Pages

Histiocytic Sarcoma Involving Cervical Vertebra: A Case Report and Review of the Literature

  • Eshagh Bahrami,
  • Masoumeh Najafi,
  • Amin Jahanbakhshi,
  • Jaber Hatam,
  • Saadat Molanaei,
  • Patrizia Ciammella and
  • Salvatore Cozzi

Histiocytic sarcoma (HS) is a rare neoplasm composed of cells with immunohistochemical characteristics of mature histiocytes. It can be disseminated or localized and usually involves the skin, spleen, and gastrointestinal tract. Primary involvement o...

  • Article
  • Open Access
8 Citations
5,372 Views
14 Pages

Patients with severe substance use disorders are often characterized by neurocognitive impairments and elevated mental health symptom load, typically associated with craving intensity and substance use relapse. There is a need to improve the predicti...

  • Systematic Review
  • Open Access
5 Citations
3,154 Views
15 Pages

(1) Background: The brainstem plays an essential role in the early stage of Parkinson’s disease (PD), but it is not widely tested in clinical examinations of PD. Vestibular-evoked myogenic potentials (VEMPs) are recognized as fundamental tools...

  • Article
  • Open Access
5 Citations
2,493 Views
13 Pages

Gender Differences in the Psychopathology of Obesity: How Relevant Is the Role of Binge Eating Behaviors?

  • Chiara Di Natale,
  • Lorenza Lucidi,
  • Chiara Montemitro,
  • Mauro Pettorruso,
  • Rebecca Collevecchio,
  • Lucia Di Caprio,
  • Luana Giampietro,
  • Liberato Aceto,
  • Giovanni Martinotti and
  • Massimo di Giannantonio

Background: Obesity is a condition that affects humans both physically and mentally. Moreover, many psychopathological conditions can be observed in obese patients that may threaten the positive outcomes of bariatric surgery. Purpose: The aim of this...

  • Article
  • Open Access
5 Citations
2,575 Views
11 Pages

Developmental Eye Movement (DEM) and King-Devick (K-D) Performance in Multiple Sclerosis

  • Amparo Gil-Casas,
  • David P. Piñero-Llorens and
  • Ainhoa Molina-Martín

Eye movement disorders have been reported in patients with multiple sclerosis (MS) as saccadic disturbances. Several methods have been described for the assessment of saccades, including the K-D and DEM tests. The performance of these tests also invo...

  • Article
  • Open Access
25 Citations
3,459 Views
14 Pages

Type 2 Diabetes Mellitus with Tight Glucose Control and Poor Pre-Injury Stair Climbing Capacity May Predict Postoperative Delirium: A Secondary Analysis

  • Kaixi Liu,
  • Yanan Song,
  • Yi Yuan,
  • Zhengqian Li,
  • Xiaoxiao Wang,
  • Wenchao Zhang,
  • Yue Li,
  • Xinning Mi,
  • Dengyang Han and
  • Yulan Rong
  • + 2 authors

(1) Background: Previous evidence demonstrates that tight glycemic control and good physical function could reduce the risk of delirium. This study aimed to investigate whether the occurrence of postoperative delirium (POD) in older hip fracture surg...

  • Article
  • Open Access
6 Citations
2,466 Views
11 Pages

During balance recovery from slip perturbations, forward flexion (elevation) of the arms serves to counterbalance the posteriorly displaced center of mass (CoM). We aimed to investigate whether aging affects modulation of arm responses to various int...

  • Article
  • Open Access
43 Citations
4,861 Views
13 Pages

PS-NPs Induced Neurotoxic Effects in SHSY-5Y Cells via Autophagy Activation and Mitochondrial Dysfunction

  • Qisheng Tang,
  • Tianwen Li,
  • Kezhu Chen,
  • Xiangyang Deng,
  • Quan Zhang,
  • Hailiang Tang,
  • Zhifeng Shi,
  • Tongming Zhu and
  • Jianhong Zhu

Polystyrene nanoparticles (PS-NPs) are organic pollutants that are widely detected in the environment and organisms, posing potential threats to both ecosystems and human health. PS-NPs have been proven to penetrate the blood–brain barrier and...

  • Article
  • Open Access
2 Citations
3,051 Views
11 Pages

A Retrospective Evaluation to Assess Reliability of Electrophysiological Methods for Diagnosis of Hearing Loss in Infants

  • Marco Mandalà,
  • Luca Mazzocchin,
  • Bryan Kevin Ward,
  • Francesca Viberti,
  • Ilaria Bindi,
  • Lorenzo Salerni,
  • Giacomo Colletti,
  • Liliana Colletti and
  • Vittorio Colletti

Background: An electrophysiological investigation with auditory brainstem response (ABR), round window electrocochleography (RW-ECoG), and electrical-ABR (E-ABR) was performed in children with suspected hearing loss with the purpose of early diagnosi...

  • Review
  • Open Access
14 Citations
10,010 Views
16 Pages

Magnetic Resonance Planimetry in the Differential Diagnosis between Parkinson’s Disease and Progressive Supranuclear Palsy

  • Andrea Quattrone,
  • Maurizio Morelli,
  • Maria G. Bianco,
  • Jolanda Buonocore,
  • Alessia Sarica,
  • Maria Eugenia Caligiuri,
  • Federica Aracri,
  • Camilla Calomino,
  • Marida De Maria and
  • Maria Grazia Vaccaro
  • + 4 authors

The clinical differential diagnosis between Parkinson’s disease (PD) and progressive supranuclear palsy (PSP) is often challenging. The description of milder PSP phenotypes strongly resembling PD, such as PSP-Parkinsonism, further increased the...

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Brain Sci. - ISSN 2076-3425