Histiocytic Sarcoma Involving Cervical Vertebra: A Case Report and Review of the Literature
Abstract
1. Introduction
2. Case Presentation
3. Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
CNS | Central nervous system |
CT | Computed tomography |
MR | Magnetic resonance |
HS | Histiocytic sarcoma |
DLBCL | Diffuse large B-cell lymphoma |
ALCL | Anaplastic large cell lymphoma |
IHC | Immunohistochemical |
PET | Positron emission tomography |
References
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Author/Year | Age/Sex | Location | IHC | Treatment | Follow-Up |
---|---|---|---|---|---|
Pileri et al. (2002) [8] | 26, male | T4, T5 | CD 68, lysozyme, S100, CD45 | Radiotherapy and autologous bone marrow transplantation at the time of relapse | After 3 years, alive in complete remisssion |
Kaushal et al. (2012) [6] | 17, male | L3 | LCA, vimentin, CD68, CD163, Ki67 20% | Surgery + radiotherapy | Disease-free 3.5 years after surgery |
Lin et al. (2012) [7] | 27, female | L3 | Cd68, vimentin, S100 | Surgery (spondylectomy) without adjuvant treatment | No recurrence after 2 years |
Patnaik et al. (2012) [2] | 22, male | T8, T9 | S100, CD38, Lysosyme | Partial excision without adjuvant treatment | Alive after 5 months |
Buonocore et al. (2005) [5] | 3, male | L4, T6 | CD68, focal S100, CD15 | Surgery and radiotherapy just to L4 and chemotherapy, and thereafter, chemoradiotherapy to pulmonary metastases | Two pulmonary nodules developed no change in the T6 lesion |
Sohn et al. (2010) [9] | 63, male | Multiple thoraco lumbar vertebra | CD68, S100 protein, CD31, CD99, vimentin weakly positive for: CD21, CD4, lysozyme | The patient refused all treatments | Died after 2 months |
The current case | 29, female | C2 | CD45, CD43, CD68, S100 | Surgery and radiotherapy | Brain metastasis after 9 months |
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Bahrami, E.; Najafi, M.; Jahanbakhshi, A.; Hatam, J.; Molanaei, S.; Ciammella, P.; Cozzi, S. Histiocytic Sarcoma Involving Cervical Vertebra: A Case Report and Review of the Literature. Brain Sci. 2022, 12, 958. https://doi.org/10.3390/brainsci12070958
Bahrami E, Najafi M, Jahanbakhshi A, Hatam J, Molanaei S, Ciammella P, Cozzi S. Histiocytic Sarcoma Involving Cervical Vertebra: A Case Report and Review of the Literature. Brain Sciences. 2022; 12(7):958. https://doi.org/10.3390/brainsci12070958
Chicago/Turabian StyleBahrami, Eshagh, Masoumeh Najafi, Amin Jahanbakhshi, Jaber Hatam, Saadat Molanaei, Patrizia Ciammella, and Salvatore Cozzi. 2022. "Histiocytic Sarcoma Involving Cervical Vertebra: A Case Report and Review of the Literature" Brain Sciences 12, no. 7: 958. https://doi.org/10.3390/brainsci12070958
APA StyleBahrami, E., Najafi, M., Jahanbakhshi, A., Hatam, J., Molanaei, S., Ciammella, P., & Cozzi, S. (2022). Histiocytic Sarcoma Involving Cervical Vertebra: A Case Report and Review of the Literature. Brain Sciences, 12(7), 958. https://doi.org/10.3390/brainsci12070958