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Applied Sciences, Volume 12, Issue 15

August-1 2022 - 601 articles

Cover Story: Extracellular vesicles (EV) represent a promising therapeutic approach for unmet clinical needs in the field of tissue engineering and regenerative medicine (TERM). Current research on native and bioengineered microvesicles and apoptotic bodies (left), exosomes and biomineralization vesicles (center), and matrix bound nanovesicles (right) aim to harness the translational and regenerative potential of these EV subtypes. Substantial translational effort has focused on the development of EV therapies for clinical application across the fields of cardiovascular, respiratory, renal, hepatic, nervous system, and wound healing medicine. While early pre-clinical and clinical results are promising, further research is required as there remain significant translational hurdles to establishing EV therapies in the field of TERM. View this paper
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Articles (601)

  • Article
  • Open Access
1 Citations
3,460 Views
15 Pages

The FaaS-Based Cloud Agnostic Architecture of Medical Services—Polish Case Study

  • Dariusz R. Augustyn,
  • Łukasz Wyciślik and
  • Mateusz Sojka

8 August 2022

In this paper, the authors, based on a case study of the Polish healthcare IT system being deployed to the cloud, show the possibilities for limiting the computing resources consumption of rarely used services. The architecture of today’s devel...

  • Article
  • Open Access
8 Citations
2,574 Views
16 Pages

Enhanced Search-and-Rescue Optimization-Enabled Secure Route Planning Scheme for Internet of Drones Environment

  • Fatma S. Alrayes,
  • Sami Dhahbi,
  • Jaber S. Alzahrani,
  • Amal S. Mehanna,
  • Mesfer Al Duhayyim,
  • Abdelwahed Motwakel,
  • Ishfaq Yaseen and
  • Amgad Atta Abdelmageed

8 August 2022

The Internet of Drones (IoD) is greatly developed and promotes many civil applications. However, it can still be prone to several security problems which threaten public safety. The issue of security poses further problems upon linking the IoD to the...

  • Article
  • Open Access
16 Citations
3,418 Views
16 Pages

Optimal and Efficient Deep Learning Model for Brain Tumor Magnetic Resonance Imaging Classification and Analysis

  • Manar Ahmed Hamza,
  • Hanan Abdullah Mengash,
  • Saud S. Alotaibi,
  • Siwar Ben Haj Hassine,
  • Ayman Yafoz,
  • Fahd Althukair,
  • Mahmoud Othman and
  • Radwa Marzouk

8 August 2022

A brain tumor (BT) is an abnormal development of brain cells that causes damage to the nerves and blood vessels. An accurate and early diagnosis of BT is important to prevent future complications. Precise segmentation of the BT provides a basis for s...

  • Article
  • Open Access
14 Citations
4,672 Views
14 Pages

8 August 2022

At the present time, the entire world is suffering from global climate change due to emissions caused by the combustion of fossil fuels. Thus, it is necessary to look for alternative power sources to generate clean electrical energy. Thermoelectric g...

  • Article
  • Open Access
6 Citations
11,695 Views
11 Pages

Do Carbon-Plated Running Shoes with Different Characteristics Influence Physiological and Biomechanical Variables during a 10 km Treadmill Run?

  • Pierre Kiesewetter,
  • Sabrina Bräuer,
  • Ralf Haase,
  • Nico Nitzsche,
  • Christian Mitschke and
  • Thomas L. Milani

8 August 2022

Footwear properties can influence physiological and biomechanical variables, which may lead to positive changes in distance running performance. One innovative development in running shoe technology is adding carbon fiber plates to increase midsole b...

  • Article
  • Open Access
24 Citations
4,751 Views
17 Pages

8 August 2022

Citrus harvesting is time-intensive and labor-intensive, relying mainly on manual harvesting. The automatic harvesting of fruit and vegetable crops can not only reduce the physical labor of fruit farmers in the harsh field environment but also greatl...

  • Article
  • Open Access
10 Citations
5,393 Views
11 Pages

Using Blockchain to Protect 3D Printing from Unauthorized Model Tampering

  • Yajing Wang,
  • Yaodong Yang,
  • Shuaipeng Suo,
  • Mingyuan Wang and
  • Weifeng Rao

8 August 2022

As three-dimensional (3D) printing technology is widely used, security issues have arisen, especially in the terminal parts of automobiles, aircraft, and 3D-printed military equipment. If the original design models or the STL (stereolithography) file...

  • Article
  • Open Access
1 Citations
2,149 Views
13 Pages

8 August 2022

Variable-period scanning beam interference lithography (VP-SBIL) can be used to fabricate varied-line-spacing (VLS) plane gratings. The exposure phase modulation method to pattern a VLS grating with a desired groove density must be carefully devised....

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Appl. Sci. - ISSN 2076-3417