You are currently viewing a new version of our website. To view the old version click .

Medical Sciences, Volume 6, Issue 4

December 2018 - 38 articles

Cover Story: This study showed that human dermal fibroblasts produce significant levels of NO depending on stimulation and glucose conditions. The nitrite level in the media is not a reliable proxy for the actual level of NO produced by the cells. Using the CellNO trap, a novel measurement system developed in our lab, we are able to accurately measure NO produced by cells grown in culture without changing established culturing protocols. If we accurately measure the actual levels of NO produced by cells cultured under specific conditions, including the temporal NO release profile, we can understand and mimic the physiological NO release at different stages of wound healing and in different pathological states. This will facilitate a smooth transition of the wound from a chronic state into resolution, consequently shortening the time to complete the healing process of diabetic foot ulcers. View this paper.
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (38)

  • Article
  • Open Access
11 Citations
5,482 Views
8 Pages

17 December 2018

Commercially available digital stethoscopes can be used as a phonocardiograph to record heart sounds. However, procuring a costly digital stethoscope may not be possible under resource-limited conditions. A low-cost, wire connected, and mobile phone-...

  • Article
  • Open Access
6 Citations
4,670 Views
9 Pages

Asymptomatic Bacteriuria and Anti-Microbial Susceptibility Patterns among Women of Reproductive Age. A Cross-Sectional Study in Primary Care, Ghana

  • Prince Afoakwa,
  • Seth Agyei Domfeh,
  • Bright Oppong Afranie,
  • Dorcas Ohui Owusu,
  • Sampson Donkor,
  • Kennedy Kormla Sakyi,
  • Richard Akesse Adom,
  • Godfred Kyeremeh,
  • Bright Afranie Okyere and
  • Emmanuel Acheampong
  • + 1 author

17 December 2018

Background: Asymptomatic bacteriuria (ASB) poses serious future clinical repercussions for reproductive women. The study determined the prevalence of asymptomatic bacteriuria along with anti-microbial susceptibility patterns among women of reproducti...

  • Review
  • Open Access
201 Citations
12,674 Views
15 Pages

Microbiota in the Gastrointestinal Tract

  • Walburga Dieterich,
  • Monic Schink and
  • Yurdagül Zopf

14 December 2018

Gut microbiota are permanent residents of humans with the highest concentrations being found in human colon. Humans get the first contact with bacteria at delivery, and microbiota are subject of permanent change during the life. The individual microb...

  • Review
  • Open Access
5 Citations
3,376 Views
10 Pages

11 December 2018

We review current management for allergic rhinitis and possible new treatments for this condition. Management of allergic rhinitis includes promotion of protective factors, avoidance of allergens, and possibly immunotherapy. In recent years, the inci...

  • Review
  • Open Access
27 Citations
4,680 Views
18 Pages

Transglutaminases in Monocytes and Macrophages

  • Huifang Sun and
  • Mari T. Kaartinen

11 December 2018

Macrophages are key players in various inflammatory disorders and pathological conditions via phagocytosis and orchestrating immune responses. They are highly heterogeneous in terms of their phenotypes and functions by adaptation to different organs...

  • Feature Paper
  • Article
  • Open Access
33 Citations
6,044 Views
13 Pages

Polyamine Homeostasis in Snyder-Robinson Syndrome

  • Tracy Murray-Stewart,
  • Matthew Dunworth,
  • Jackson R. Foley,
  • Charles E. Schwartz and
  • Robert A. Casero

7 December 2018

Loss-of-function mutations of the spermine synthase gene (SMS) result in Snyder-Robinson Syndrome (SRS), a recessive X-linked syndrome characterized by intellectual disability, osteoporosis, hypotonia, speech abnormalities, kyphoscoliosis, and seizur...

  • Review
  • Open Access
16 Citations
3,962 Views
16 Pages

New Insights in Bladder Cancer Diagnosis: Urinary miRNAs and Proteins

  • Gökçe Güllü Amuran,
  • Irem Peker Eyuboglu,
  • Ilker Tinay and
  • Mustafa Akkiprik

7 December 2018

Bladder cancer is the 10th-most common cancer worldwide. The diagnosis and follow-up of patients require costly invasive methods and due to these expenses, bladder cancer continues to be one of the expensive malignancies. Early diagnosis is crucial i...

  • Perspective
  • Open Access
3 Citations
3,456 Views
12 Pages

29 November 2018

The launch of ‘Rapid Recommendations’ by the Grading of Recommendations Assessment, Development and Evaluation (GRADE) group, in collaboration with Making GRADE the Irresistible Choice (MAGIC) and the British Medical Journal (BMJ), is a very interest...

  • Review
  • Open Access
117 Citations
11,162 Views
14 Pages

Idiopathic Pulmonary Fibrosis: Epidemiology, Natural History, Phenotypes

  • Jaume Sauleda,
  • Belén Núñez,
  • Ernest Sala and
  • Joan B. Soriano

29 November 2018

Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial pneumonias. It is characterized by a chronic, progressive, fibrotic interstitial lung disease of unknown cause that occurs primarily in older adults. Its prevalence...

of 4

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Med. Sci. - ISSN 2076-3271Creative Common CC BY license