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OK-432 Administration Inhibits Murine Allergic Rhinitis at the Induction Phase, through the Macrophage Activation with TLR2 Signaling Pathway
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Early Intervention is Important to Prevent Sensitization to New Allergens

Department of Otolaryngology, Osaka Medical College, 2-7 Daigakumachi Takatsuki, Osaka 569-8686, Japan
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Author to whom correspondence should be addressed.
Med. Sci. 2018, 6(4), 114; https://doi.org/10.3390/medsci6040114
Received: 7 November 2018 / Revised: 3 December 2018 / Accepted: 7 December 2018 / Published: 11 December 2018
(This article belongs to the Special Issue Allergic Rhinitis: Epidemiology, Prevention and Management)
We review current management for allergic rhinitis and possible new treatments for this condition. Management of allergic rhinitis includes promotion of protective factors, avoidance of allergens, and possibly immunotherapy. In recent years, the incidence of allergic rhinitis has increased in many countries. Early intervention at different stages is an important part of management. Allergic disease in infants has been described as the allergic march, commencing with atopic dermatitis accompanied by infantile asthma and progressing to perennial allergic rhinitis induced by house dust mite allergy. In order to prevent polysensitization, allergen-specific immunotherapy should probably be initiated at an earlier age, especially in children with rhinitis who show monosensitization to house dust mite antigens. View Full-Text
Keywords: allergic rhinitis; early intervention; antigen exposure; immunotherapy allergic rhinitis; early intervention; antigen exposure; immunotherapy
MDPI and ACS Style

Terada, T.; Kawata, R. Early Intervention is Important to Prevent Sensitization to New Allergens. Med. Sci. 2018, 6, 114.

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