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Medical Sciences, Volume 12, Issue 4

2024 December - 26 articles

Cover Story: Our data demonstrated that self-directed rehabilitation (SDR), guided by a smartphone-based care management platform (sbCMP), was utilized without adjunct physical therapy after arthroplasty in patients enrolled in this study more frequently in the early period of the pandemic, when restricted access was common. Importantly, both objective and subjective measures of recovery, including step counts, KOOS JR, and HOOS JR scores did not vary according to the period of the pandemic, suggesting that SDR provided by the sbCMP can be feasibly and effectively utilized, particularly when access to in-person physical therapy is hindered. View this paper
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Articles (26)

  • Article
  • Open Access
3 Citations
1,764 Views
14 Pages

Could Fibrin Sealants (TISSEELTM) Be Effective in the Management of Burn Injuries? A Histopathological Study in Rats

  • Christina Nikolaou,
  • Maximos Frountzas,
  • Dimitrios Schizas,
  • Vasilios Pergialiotis,
  • Emmanouil I. Kapetanakis,
  • Konstantinos Kontzoglou,
  • Despina N. Perrea,
  • Efthymios Koniaris,
  • Stylianos Kykalos and
  • Dimitrios Iliopoulos

19 December 2024

Background: Burn injuries remain a major clinical problem worldwide, which require special management by experienced plastic surgeons. However, they cannot be available in every healthcare unit; consequently, there is a need for effective treatment o...

  • Case Report
  • Open Access
3 Citations
2,230 Views
9 Pages

An Unusual Case of Nephrotic Range Proteinuria in a Short-Standing Type 1 Diabetic Patient with Newly Diagnosed Systemic Lupus Erythematosus: A Case Report and Literature Review

  • Marco Dominguez Davalos,
  • José C. De La Flor,
  • Carlos Bedia Castillo,
  • Roxana Lipa Chancolla,
  • Celia Rodríguez Tudero,
  • Jacqueline Apaza,
  • Rocío Zamora and
  • Michael Cieza-Terrones

16 December 2024

Background: Lupus podocytopathy (LP) is a non-immune complex-mediated glomerular lesion in systemic lupus erythematosus (SLE), characterized by the diffuse effacement of podocyte processes without immune complex deposition or with only mesangial immu...

  • Essay
  • Open Access
1 Citations
2,244 Views
7 Pages

14 December 2024

Objective: This study aims to investigate the possible effects of gestational diabetes mellitus (GDM) on fetal heart structure and the relationship of this effect with maternal blood sugar control. Materials and Methods: In this cross-sectional study...

  • Review
  • Open Access
8 Citations
3,771 Views
15 Pages

Molecular Mimicry Between Gut Microbiome and Rheumatoid Arthritis: Current Concepts

  • Anandanarayan Muruganandam,
  • Filippo Migliorini,
  • Naveen Jeyaraman,
  • Raju Vaishya,
  • Sangeetha Balaji,
  • Swaminathan Ramasubramanian,
  • Nicola Maffulli and
  • Madhan Jeyaraman

12 December 2024

Rheumatoid arthritis (RA) represents an autoimmune condition impacted by a combination of genetic and environmental factors, with the gut microbiome (GMB) being one of the influential environmental factors. Patients with RA display notable modificati...

  • Article
  • Open Access
3 Citations
2,233 Views
18 Pages

11 December 2024

Background/Objective: Environmental exposures, such as heavy metals, can significantly affect physical activity, an important determinant of health. This study explores the effect of physical activity on combined exposure to cadmium, lead, and mercur...

  • Article
  • Open Access
1 Citations
2,335 Views
14 Pages

The Impact of Tumor Stage and Histopathology on Survival Outcomes in Esophageal Cancer Patients over the Past Decade

  • Ayrton Bangolo,
  • Vignesh Krishnan Nagesh,
  • Grace Simonson,
  • Abhishek Thapa,
  • Arun Ram,
  • Nithin Jayan Santhakumari,
  • Rayan Chamroukh,
  • Vivek Joseph Varughese,
  • Shallot Nareeba and
  • Simcha Weissman
  • + 19 authors

9 December 2024

Background: Esophageal cancer (EC) is the sixth leading cause of cancer-related mortality worldwide, continuing to be a significant public health concern. The purpose of this study is to assess the impact of staging and histopathology of EC on associ...

  • Article
  • Open Access
3 Citations
1,989 Views
10 Pages

Evaluating Self-Directed Rehabilitation for Knee and Hip Arthroplasty During the COVID-19 Pandemic: A Multicenter Study

  • Todd M. Miner,
  • Mike B. Anderson,
  • David C. Van Andel,
  • Robert E. Neher,
  • Roberta E. Redfern and
  • Paul J. Duwelius

26 November 2024

The COVID-19 pandemic has triggered the adoption of new technologies to reduce the need for in-person physical therapy (PT). This study evaluated the impact of the COVID-19 pandemic on PT utilization and outcomes of patients prescribed a smartphone-b...

  • Article
  • Open Access
5 Citations
2,694 Views
15 Pages

The Impact of Telemonitoring and Telehealth Coaching on General Nutrition Knowledge in Overweight and Obese Individuals: A Pilot Randomized Controlled Trial

  • Noura M. S. Eid,
  • Ebtisam A. Al-Ofi,
  • Sumia Enani,
  • Rana H. Mosli,
  • Raneem R. Saqr,
  • Karimah M. Qutah and
  • Sara M. S. Eid

22 November 2024

(1) Background: General nutrition knowledge is a fundamental pillar of well-being and healthy lifestyles. This study aimed to measure the general nutrition knowledge questionnaire (GNKQ) scores of overweight and obese participants who joined a pilot...

  • Article
  • Open Access
1 Citations
2,522 Views
11 Pages

Hemin Promotes Higher Effectiveness of Aminolevulinic-Photodynamic Therapy (ALA-PDT) in A549 Lung Cancer Cell Line by Interrupting ABCG2 Expression

  • Anantya Pustimbara,
  • Rahma Wirdatul Umami,
  • Nurul Muhammad Prakoso,
  • Anna Rozaliyani,
  • Jamal Zaini,
  • Astari Dwiranti,
  • Shun-ichiro Ogura and
  • Anom Bowolaksono

17 November 2024

Background/Objectives: Due to concerns about drug resistance and side effects, the discovery of improved drugs for lung cancer has attracted studies to find an effective and safe treatment. Aminolevulinic acid-mediated photodynamic therapy (ALA-PDT)...

  • Article
  • Open Access
1 Citations
1,714 Views
8 Pages

12 November 2024

Purpose: To assess (I) whether, in autopsy-proven lethal intoxications with opiates/opioids, a dilatation of the common bile duct (CBD) is still visible in postmortem computed tomography (PMCT) and (II) if a dilatation of the CBD might also be measur...

  • Systematic Review
  • Open Access
3 Citations
5,562 Views
23 Pages

Beta-Blocker Use in Patients Undergoing Non-Cardiac Surgery: A Systematic Review and Meta-Analysis

  • Doménica Herrera Hernández,
  • Bárbara Abreu,
  • Tania Siu Xiao,
  • Andreina Rojas,
  • Kevin López Romero,
  • Valentina Contreras,
  • Sol Villa Nogueyra,
  • Zulma Sosa,
  • Samantha M. Alvarez and
  • Ernesto Calderón Martinez
  • + 1 author

11 November 2024

Background: The use of beta-blockers in the perioperative period has been widely investigated due to their potential to reduce the risk of major adverse cardiovascular and cerebrovascular events (MACCE) and mortality; yet their overall impact on vari...

  • Article
  • Open Access
2,818 Views
12 Pages

The Impact of Adverse Childhood Experiences on Asthma Severity in US Adults

  • Chukwuemeka E. Ogbu,
  • Ioannis Stouras,
  • Chisa O. Oparanma,
  • Stella C. Ogbu and
  • Chinazor Umerah

11 November 2024

Background/objectives: The association between adverse childhood experiences (ACEs) and asthma severity among United States (US) adults with asthma has not been well documented. In addition, whether gender differences exist in this association has be...

  • Article
  • Open Access
2 Citations
2,420 Views
6 Pages

Association Between Asian Flush and Satisfaction of Sleep via Alcohol Consumption Status in a Sample of Japanese Participants

  • Yuji Shimizu,
  • Tomokatsu Yoshida,
  • Keiko Ito,
  • Kumiko Terada,
  • Nagisa Sasaki,
  • Eiko Honda and
  • Kazushi Motomura

8 November 2024

Background: The reddening of the face and neck following alcohol consumption is known as Asian flush. Although genetic factors related to Asian flush have been reported to be inversely associated with duration of sleep, no study has reported an assoc...

  • Article
  • Open Access
1 Citations
2,835 Views
11 Pages

Investigating the Matrix of Factor V Leiden (G1691A), Factor II Prothrombin (G2021A), MTHFR C677T and A1298G Polymorphisms in Greek Population: A Preliminary Study

  • Maria Spanoudaki,
  • Aikaterini Itziou,
  • Antonios Cheimaras,
  • Orestis Tsiripidis,
  • Grigoris Risvas,
  • Naysika Tsitlakidou and
  • Vasileios Balis

5 November 2024

Background: Thrombophilia, characterized by an increased risk of thrombosis, can result from genetic polymorphisms in clotting factors. This study aims to investigate the prevalence of factor V Leiden (G1691A), factor II prothrombin (G20210A), and MT...

  • Article
  • Open Access
2 Citations
2,950 Views
9 Pages

Survival Outcomes of U.S. Patients with CMML: A Two-Decade Analysis from the SEER Database

  • Ayrton Bangolo,
  • Behzad Amoozgar,
  • Abhishek Thapa,
  • Wardah Bajwa,
  • Vignesh K. Nagesh,
  • Yaryna Nyzhnyk,
  • Rakshanda Banu,
  • Tirth Bhavsar,
  • Lili Zhang and
  • Simcha Weissman
  • + 19 authors

31 October 2024

Background: Chronic Myelomonocytic Leukemia (CMML) is a rare and aggressive form of leukemia with characteristics of both myeloproliferative neoplasms (MPNs) and myelodysplastic syndromes (MDSs). This study aims to explore the clinical features, surv...

  • Article
  • Open Access
2 Citations
3,723 Views
17 Pages

Comparing NIRS and Pulse Oximetry for Cerebral Oxygen Saturation During Hypoxia Testing

  • Vasilios Alevizakos,
  • Andreas Werner,
  • Lisa-Marie Schiller,
  • Constantin von See and
  • Marcus Schiller

24 October 2024

Objective: This study evaluates the suitability of cerebral oximetry using near-infrared spectroscopy (NIRS) compared to traditional pulse oximetry (SpO2) for measuring cerebral oxygen saturation during hypoxia testing, aiming to enhance safety durin...

  • Case Report
  • Open Access
2 Citations
2,676 Views
11 Pages

Experience of Hereditary Amyloidosis with Rare Variant in Ecuador: Case Reports

  • Diana Elizabeth Luzuriaga Carpio,
  • Borys Roberto Abrigo Maldonado and
  • Humberto Villacorta

21 October 2024

More than approximately 120 transthyretin mutations are known. Their clinical presentation is heterogeneous, as the course of disease onset depends on genetic variation and level of penetrance. They are little known in Ecuador, and some of the report...

  • Article
  • Open Access
1 Citations
3,020 Views
12 Pages

Predicting Invasiveness in Lepidic Pattern Adenocarcinoma of Lung: Analysis of Visual Semantic and Radiomic Features

  • Sean F. Johnson,
  • Seyed Mohammad Hossein Tabatabaei,
  • Grace Hyun J. Kim,
  • Bianca E. Villegas,
  • Matthew Brown,
  • Scott Genshaft,
  • Robert D. Suh,
  • Igor Barjaktarevic,
  • William Dean Wallace and
  • Fereidoun Abtin

18 October 2024

Objectives: To differentiate invasive lepidic predominant adenocarcinoma (iLPA) from adenocarcinoma in situ (AIS)/minimally invasive adenocarcinoma (MIA) of lung utilizing visual semantic and computer-aided detection (CAD)-based texture features on s...

  • Article
  • Open Access
2 Citations
1,943 Views
7 Pages

Impact of Neutropenia on Clinical Outcomes after Lung Transplantation

  • Raquel Sanabrias Fernández de Sevilla,
  • Ana Concepción Sánchez Cerviño,
  • Rosalía Laporta Hernández,
  • Myriam Aguilar Pérez,
  • Christian García Fadul,
  • Sarela García-Masedo Fernández,
  • Amelia Sánchez Guerrero and
  • María Piedad Ussetti Gil

16 October 2024

Background/Objectives: Neutropenia is a frequent complication among solid organ transplant (SOT) recipients receiving immunosuppressive therapy and antimicrobial prophylaxis. However, there are limited studies analysing the frequency and impact of ne...

  • Review
  • Open Access
11 Citations
7,667 Views
23 Pages

Novel Therapeutic Approach for Obesity: Seaweeds as an Alternative Medicine with the Latest Conventional Therapy

  • Rajesh Yadav,
  • Ankita Nigam,
  • Richa Mishra,
  • Saurabh Gupta,
  • Anis Ahmad Chaudhary,
  • Salah-Ud-Din Khan,
  • Eman Abdullah almuqri,
  • Zakir Hassain Ahmed,
  • Sarvesh Rustagi and
  • Sanjay Kumar
  • + 1 author

13 October 2024

The prevalence of overweight and obesity is increasing worldwide. Common comorbidities related to obesity, significantly polygenic disorders, cardiovascular disease, and heart conditions affect social and monetary systems. Over the past decade, resea...

  • Technical Note
  • Open Access
1,226 Views
4 Pages

One-Step Cannulation and Distance Measurement during Aortic Branched Endograft Repair: The Neuron Catheter Trick

  • Gioele Simonte,
  • Gianluigi Fino,
  • Gianbattista Parlani,
  • Rachele Simonte and
  • Giacomo Isernia

6 October 2024

Purpose: This paper aims to describe a straightforward, efficient, and reliable technique to simplify cannulation maneuvers during aortic branched endograft repair. Technique: The suggested approach utilizes the Penumbra Neuron Select catheter, which...

  • Review
  • Open Access
3 Citations
9,623 Views
21 Pages

The Increasing Problem of Resistant Hypertension: We’ll Manage till Help Comes!

  • Francesco Natale,
  • Rosa Franzese,
  • Ettore Luisi,
  • Noemi Mollo,
  • Luigi Marotta,
  • Achille Solimene,
  • Saverio D’Elia,
  • Paolo Golino and
  • Giovanni Cimmino

4 October 2024

Arterial hypertension remains the major cardiovascular risk worldwide. It is estimated that under 50 years of age one in every three adults is hypertensive while beyond the age of 50 the prevalence is almost 50% globally. The latest World Health Orga...

  • Article
  • Open Access
2 Citations
2,021 Views
7 Pages

Fractional Exhaled Nitric Oxide (FeNO) in Biomass Smoke-Associated Chronic Obstructive Pulmonary Disease

  • Juan Silva-Gallardo,
  • Raúl H. Sansores,
  • Alejandra Ramírez-Venegas,
  • Robinson E. Robles Hernández,
  • Gustavo I. Centeno-Saenz and
  • Rafael J. Hernández-Zenteno

4 October 2024

Chronic Obstructive Pulmonary Disease (COPD) is a disease characterized by local and systemic inflammation independently of the risk factor; during the exacerbations, such inflammation is accentuated and amplified. A practical inflammatory marker and...

  • Article
  • Open Access
5 Citations
2,717 Views
10 Pages

2 October 2024

Background: Cardiovascular diseases (CVD) are a leading cause of mortality worldwide, influenced by genetic, environmental, and behavioral factors. This study examines the relationship between heavy metal exposure, chronic physiological stress (allos...

  • Article
  • Open Access
2 Citations
2,029 Views
9 Pages

Changes in Central Sensitivity to Thyroid Hormones vs. Urine Iodine during Pregnancy

  • Ioannis Ilias,
  • Charalampos Milionis,
  • Maria Alexiou,
  • Ekaterini Michou,
  • Chrysi Karavasili,
  • Evangelia Venaki,
  • Kostas Markou,
  • Irini Mamali and
  • Eftychia Koukkou

27 September 2024

Introduction/Aim: Central sensitivity to thyroid hormones refers to the responsiveness of the hypothalamic–pituitary–thyroid (HPT) axis to changes in circulating free thyroxine (fT4). Although dose–response relationships between thy...

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Med. Sci. - ISSN 2076-3271