Animals, Volume 12, Issue 8
2022 April-2 - 109 articles
Cover Story: The equine fecal microbiome is dynamic and not yet well understood. Inflammatory conditions of the gastrointestinal tract are common in the horse and can be catastrophic. Alterations in this microbial community or its metabolic profile can lead to imbalances resulting in diarrhea or other health conditions. The objective of this study was to examine the effects of intravenous antibiotics on the equine fecal microbiome in healthy horses. Four groups of four horses each were studied over time and were administered either intravenous ceftiofur, oxytetracycline, enrofloxacin, or saline (control group). Significant microbiome changes developed shortly after starting ceftiofur and enrofloxacin, which had lasting effects on bacterial community structures. Such changes could underlie development of inflammatory conditions of the gastrointestinal tract seen during or after antibiotic therapy. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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