- Article
The Autotrophic Core: An Ancient Network of 404 Reactions Converts H2, CO2, and NH3 into Amino Acids, Bases, and Cofactors
- Jessica L. E. Wimmer,
- Andrey do Nascimento Vieira,
- Joana C. Xavier,
- Karl Kleinermanns,
- William F. Martin and
- Martina Preiner
The metabolism of cells contains evidence reflecting the process by which they arose. Here, we have identified the ancient core of autotrophic metabolism encompassing 404 reactions that comprise the reaction network from H2, CO2, and ammonia (NH3) to...

