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Microorganisms, Volume 10, Issue 10

2022 October - 216 articles

Cover Story: Biofilm formation by Salmonella typhimurium and Escherichia coli is a common ancient multicellular behavior relevant in cell–cell and inter-organism interactions equally, as in interaction with biotic and abiotic surfaces. Two characteristic extracellular matrix components amyloid curli fimbriae and the exopolysaccharide cellulose promote biofilm formation. The expression of these biofilm-promoting factors is regulated by the orphan transcriptional regulator CsgD. We found that GreA/GreB, proteins that interact with RNA polymerase to selectively overcome transcriptional pausing, are required for the expression of the csgD operon and consequently for biofilm formation. In the model proposed, the Gre factors suppress transcriptional pausing at the 5′-UTR of the csgD gene. View this paper
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Articles (216)

  • Article
  • Open Access
11 Citations
4,024 Views
13 Pages

Vaginal Lactobacillus Impair Candida Dimorphic Switching and Biofilm Formation

  • Carola Parolin,
  • Vanessa Croatti,
  • Barbara Giordani and
  • Beatrice Vitali

Lactobacillus spp. generally dominate the vaginal microbiota and prevent pathogen adhesion and overgrowth, including Candida spp., by various mechanisms. Although Candida spp. can be commensal, in certain conditions they can become pathogenic, causin...

  • Brief Report
  • Open Access
4 Citations
2,453 Views
4 Pages

SARS-CoV-2 Omicron BA.2.75 Variant May Be Much More Infective than Preexisting Variants Based on In Silico Model

  • Aki Sugano,
  • Yutaka Takaoka,
  • Haruyuki Kataguchi,
  • Mika Ohta,
  • Shigemi Kimura,
  • Masatake Araki,
  • Yoshitomo Morinaga and
  • Yoshihiro Yamamoto

Previously, we developed a mathematical model via molecular simulation analysis to predict the infectivity of six SARS-CoV-2 variants. In this report, we aimed to predict the relative risk of the recent new variants of SARS-CoV-2 based on our previou...

  • Article
  • Open Access
11 Citations
3,988 Views
20 Pages

Screening of Endophytic Bacteria of Leucojum aestivum ‘Gravety Giant’ as a Potential Source of Alkaloids and as Antagonist to Some Plant Fungal Pathogens

  • Yuka Munakata,
  • Rosella Spina,
  • Sophie Slezack-Deschaumes,
  • Julie Genestier,
  • Alain Hehn and
  • Dominique Laurain-Mattar

Leucojum aestivum is a medicinal plant belonging to the Amaryllidaceae family well known as a producer of alkaloids such as galanthamine and lycorine. However, the endophytic microbes that colonize different plant tissues without causing any damage h...

  • Article
  • Open Access
18 Citations
5,280 Views
21 Pages

Probiotic bacteria modulate macrophage immune inflammatory responses, with functional cytokine responses determined by macrophage subset polarisation, stimulation and probiotic strain. Mucosal macrophages exhibit subset functional heterogeneity but a...

  • Article
  • Open Access
2 Citations
2,894 Views
14 Pages

StcU-2 Gene Mutation via CRISPR/Cas9 Leads to Misregulation of Spore-Cyst Formation in Ascosphaera apis

  • Tessema Aynalem,
  • Lifeng Meng,
  • Awraris Getachew,
  • Jiangli Wu,
  • Huimin Yu,
  • Jing Tan,
  • Nannan Li and
  • Shufa Xu

Ascosphaera apis is the causative agent of honey bee chalkbrood disease, and spores are the only known source of infections. Interference with sporulation is therefore a promising way to manage A. apis. The versicolorin reductase gene (StcU-2) is a k...

  • Article
  • Open Access
21 Citations
3,316 Views
16 Pages

Translocation and Dissemination of Gut Bacteria after Severe Traumatic Brain Injury

  • Weijian Yang,
  • Qiang Yuan,
  • Zhiqi Li,
  • Zhuoying Du,
  • Gang Wu,
  • Jian Yu and
  • Jin Hu

Enterobacteriaceae are often found in the lungs of patients with severe Traumatic Brain Injury (sTBI). However, it is unknown whether these bacteria come from the gut microbiota. To investigate this hypothesis, the mice model of sTBI was used in this...

  • Article
  • Open Access
6 Citations
3,145 Views
22 Pages

Epidermal Microbiomes of Leopard Sharks (Triakis semifasciata) Are Consistent across Captive and Wild Environments

  • Asha Z. Goodman,
  • Bhavya Papudeshi,
  • Michael P. Doane,
  • Maria Mora,
  • Emma Kerr,
  • Melissa Torres,
  • Jennifer Nero Moffatt,
  • Lais Lima,
  • Andrew P. Nosal and
  • Elizabeth Dinsdale

Characterizations of shark-microbe systems in wild environments have outlined patterns of species-specific microbiomes; however, whether captivity affects these trends has yet to be determined. We used high-throughput shotgun sequencing to assess the...

  • Article
  • Open Access
10 Citations
3,261 Views
23 Pages

Endophytic Bacteria Associated with Origanum heracleoticum L. (Lamiaceae) Seeds

  • Giulia Semenzato,
  • Teresa Faddetta,
  • Sara Falsini,
  • Sara Del Duca,
  • Antonia Esposito,
  • Anna Padula,
  • Claudia Greco,
  • Nadia Mucci,
  • Marco Zaccaroni and
  • Renato Fani
  • + 2 authors

Seed-associated microbiota are believed to play a crucial role in seed germination, seedling establishment, and plant growth and fitness stimulation, due to the vertical transmission of a core microbiota from seeds to the next generations. It might b...

  • Article
  • Open Access
6 Citations
3,280 Views
13 Pages

Microbiome of Citrullus colocynthis (L.) Schrad. Reveals a Potential Association with Non-Photosynthetic Cyanobacteria

  • Miranda Procter,
  • Biduth Kundu,
  • Naganeeswaran Sudalaimuthuasari,
  • Raja S. AlMaskari,
  • Esam E. Saeed,
  • Khaled M. Hazzouri and
  • Khaled M. A. Amiri

Citrullus colocynthis grows in the sandy desert soil of the Arabian Peninsula with limited access to water, aside from occasional precipitation or dew. Understanding its ability to produce water-filled fruit and nutrient-rich seeds despite the harsh...

  • Article
  • Open Access
12 Citations
3,207 Views
12 Pages

‘Hongyang’ kiwifruit (Actinidia chinensis, cultivar ‘Hongyang’) black spot disease is caused by the fungal pathogen Didymella glomerata, and is a serious disease, causing considerable losses to the kiwifruit industry during gr...

  • Article
  • Open Access
5 Citations
2,727 Views
15 Pages

Gene Regulatory Network of the Noncoding RNA Qrr5 Involved in the Cytotoxicity of Vibrio parahaemolyticus during Infection

  • Fei Zha,
  • Rui Pang,
  • Shixuan Huang,
  • Jumei Zhang,
  • Juan Wang,
  • Moutong Chen,
  • Liang Xue,
  • Qinghua Ye,
  • Shi Wu and
  • Qingping Wu
  • + 4 authors

Small non-coding RNAs (sRNAs) in bacteria are important regulatory molecules for controlling virulence. In Vibrio spp., Qrr sRNAs are critical for quorum-sensing pathways and regulating the release of some virulence factors. However, the detailed rol...

  • Review
  • Open Access
37 Citations
4,185 Views
16 Pages

In recent years, as an emerging material, nanomaterials have rapidly expanded from laboratories to large-scale industrial productions. Along with people’s productive activities, these nanomaterials can enter the natural environment of soil, wat...

  • Article
  • Open Access
10 Citations
3,273 Views
16 Pages

Plant and Soil Core Mycobiomes in a Two-Year Sorghum–Legume Intercropping System of Underutilized Crops in South Africa

  • Gilmore T. Pambuka,
  • Tonjock Rosemary Kinge,
  • Soumya Ghosh,
  • Errol D. Cason,
  • Martin M. Nyaga and
  • Marieka Gryzenhout

Fungal communities form close beneficial (mutualists) or detrimental (pathogens) associations with their plant hosts. Their diversity and abundance can be affected by agricultural practices which include cropping systems such as rotations and intercr...

  • Article
  • Open Access
2 Citations
2,919 Views
17 Pages

The enzyme that, in Saccharomyces cerevisiae, catalyzes the last step in both proline synthesis and arginine catabolism, δ1-pyrroline-5-carboxylate (P5C) reductase, was purified to near homogeneity and characterized thoroughly. Retention patter...

  • Article
  • Open Access
19 Citations
3,079 Views
16 Pages

Biochar application can enhance soil health and alter soil bacterial community structure. However, knowledge relating to biochar on soil nutrients of mountainous apple orchards and then assessing its effect on soil health, especially on soil microorg...

  • Article
  • Open Access
7 Citations
4,169 Views
11 Pages

Bloodstream infections are a leading cause of morbidity and mortality. The rapid diagnostic testing of positive blood cultures (PBCs) shortens times to effective therapy and the de-escalation of broad-spectrum empiric therapy. This is the first study...

  • Article
  • Open Access
5 Citations
2,422 Views
14 Pages

Epidemiological and Cytokine Profile of Patients with Pulmonary and Extrapulmonary Tuberculosis in a Population of the Brazilian Amazon

  • Maria Alice Freitas Queiroz,
  • Sandra Souza Lima,
  • Ednelza da Silva Graça Amoras,
  • Francisca Dayse Martins de Sousa,
  • Iury de Paula Souza,
  • Juliana Abreu Lima Nunes,
  • Igor Brasil-Costa,
  • Izaura Maria Vieira Cayres-Vallinoto,
  • Ricardo Ishak and
  • Antonio Carlos Rosário Vallinoto

Several factors are associated with the development of different clinical forms of tuberculosis (TB). The present study evaluated epidemiological variables and cytokine levels in samples from 89 patients with TB (75 with pulmonary TB and 14 with extr...

  • Article
  • Open Access
2 Citations
2,347 Views
9 Pages

We previously reported trends in pneumococcal nasopharyngeal carriage in the post-PCV13 era as detected by conventional culture methods. Our current aim is to assess if there are fundamental differences in the clinical and demographic features of chi...

  • Article
  • Open Access
17 Citations
3,500 Views
17 Pages

Initial pH Conditions Shape the Microbial Community Structure of Sewage Sludge in Batch Fermentations for the Improvement of Volatile Fatty Acid Production

  • Ylenia Di Leto,
  • Fanny Claire Capri,
  • Antonio Mineo,
  • Alida Cosenza,
  • Giuseppe Gallo,
  • Rosa Alduina and
  • Giorgio Mannina

Conversion of wastewater treatment plants into biorefineries is a sustainable alternative for obtaining valuable compounds, thus reducing pollutants and costs and protecting the environment and human health. Under specific operating conditions, micro...

  • Review
  • Open Access
47 Citations
9,328 Views
17 Pages

Opposite Sides of Pantoea agglomerans and Its Associated Commercial Outlook

  • Adriana Sturion Lorenzi,
  • Maria Letícia Bonatelli,
  • Mathias Ahii Chia,
  • Leonardo Peressim and
  • Maria Carolina Quecine

Multifaceted microorganisms such as the bacterium Pantoea colonize a wide range of habitats and can exhibit both beneficial and harmful behaviors, which provide new insights into microbial ecology. In the agricultural context, several strains of Pant...

  • Article
  • Open Access
3 Citations
3,566 Views
16 Pages

Long-Term Effects of Single-Dose Cephalosporin or Macrolide Use on the Prevalence of AmpC and Extended-Spectrum β-Lactamase Producing Escherichia coli in the Feces of Beef Cattle

  • Gizem Levent,
  • Ashlynn Schlochtermeier,
  • Javier Vinasco,
  • Jenny Jennings,
  • John Richeson,
  • Samuel E. Ives,
  • Keri N. Norman,
  • Sara D. Lawhon,
  • Guy H. Loneragan and
  • H. Morgan Scott

Extended-spectrum-β-lactamase (ESBL) and AmpC-lactamase-producing Enterobacteriaceae are serious public health threats. Due to an increasing number of reports of ESBL and AmpC producing Escherichia coli in agricultural settings, it is critical t...

  • Article
  • Open Access
31 Citations
8,068 Views
15 Pages

The purpose of this study was to evaluate the genotypic and phenotypic toxicity of Enterococcus faecalis MG5206 and Enterococcus faecium MG5232 isolated from kimchi (fermented vegetable cabbage). In this study, the genotypic toxicity of the strains M...

  • Review
  • Open Access
57 Citations
8,590 Views
20 Pages

Fermentation of Microalgal Biomass for Innovative Food Production

  • Cristiana Garofalo,
  • Alessandra Norici,
  • Lorenzo Mollo,
  • Andrea Osimani and
  • Lucia Aquilanti

Fermentation is an ancient method used worldwide to process and preserve food while enhancing its nutraceutical profile. Alga-based fermented products have recently been developed and tested due to growing interest in healthy sustainable diets, which...

  • Article
  • Open Access
20 Citations
3,683 Views
19 Pages

Effect of Lactobacteria on Bioactive Peptides and Their Sequence Identification in Mature Cheese

  • Marina Kurbanova,
  • Roman Voroshilin,
  • Oksana Kozlova and
  • Victor Atuchin

An in silico study that featured the effect of starter cultures on the bioactivity and other health benefits of peptides in semi-hard cheese is presented in this contribution. Model Caciotta-type cheese samples were obtained in laboratory conditions...

  • Brief Report
  • Open Access
3 Citations
2,261 Views
6 Pages

Outliers Matter—Correlation between S1 IgG SARS-CoV-2 Antibodies and Neutralizing SARS-CoV-2 Antibodies

  • Berthold Hocher,
  • Anne Schönbrunn,
  • Xin Chen,
  • Bernhard K. Krämer and
  • Volker von Baehr

Vaccination against the SARS-CoV-2 virus or infection with SARS-CoV-2 will lead to the development of IgG antibodies against the S1 protein of the SARS-CoV-2 virus. However, even despite having high levels of IgG antibodies against the S1 protein of...

  • Article
  • Open Access
20 Citations
3,949 Views
13 Pages

Plasma Gut Microbe-Derived Metabolites Associated with Peripheral Artery Disease and Major Adverse Cardiac Events

  • Karen J. Ho,
  • Joel L. Ramirez,
  • Rohan Kulkarni,
  • Katharine G. Harris,
  • Irene Helenowski,
  • Liqun Xiong,
  • C. Keith Ozaki and
  • S. Marlene Grenon

Cardiovascular diseases are associated with gut dysbiosis, but the role of microbe-derived metabolites as biomarkers or modulators of cardiovascular disease are not well understood. This is a targeted metabolomics study to investigate the association...

  • Article
  • Open Access
9 Citations
7,095 Views
19 Pages

Geno- and Phenotypic Characteristics of a Klebsiella pneumoniae ST20 Isolate with Unusual Colony Morphology

  • Katharina Sydow,
  • Elias Eger,
  • Michael Schwabe,
  • Stefan E. Heiden,
  • Jürgen A. Bohnert,
  • Sören Franzenburg,
  • Christoph Jurischka,
  • Peter Schierack and
  • Katharina Schaufler

Klebsiella pneumoniae is a common member of the intestinal flora of vertebrates. In addition to opportunistic representatives, hypervirulent (hvKp) and antibiotic-resistant K. pneumoniae (ABR-Kp) occur. While ABR-Kp isolates often cause difficult-to-...

  • Review
  • Open Access
8 Citations
3,042 Views
16 Pages

The Changes in Bacterial Microbiome Associated with Immune Disorder in Allergic Respiratory Disease

  • Juanjuan Lyu,
  • Fangfang Kou,
  • Xiangyu Men,
  • Yinhui Liu,
  • Li Tang and
  • Shu Wen

Allergic respiratory disease is a worldwide and increasingly prevalent health problem. Many researchers have identified complex changes in the microbiota of the respiratory and intestinal tracts in patients with allergic respiratory diseases. These a...

  • Article
  • Open Access
5 Citations
2,548 Views
12 Pages

Spent mushroom substrates (SMSs) can be developed as a biofertilizer through composting. Here, we investigated the dynamics of bacterial and fungal communities during commercial composting and the effect of swine and poultry manure on their communiti...

  • Article
  • Open Access
8 Citations
2,534 Views
12 Pages

The performance of the urine reagent strips (URS) in detecting the presence and estimating the intensity of Schistosoma haematobium infection was evaluated using urine filtration microscopy as a reference standard. Urine samples collected from 1288 s...

  • Review
  • Open Access
87 Citations
24,719 Views
20 Pages

The intestine represents the body’s largest interface between internal organs and external environments except for its nutrient and fluid absorption functions. It has the ability to sense numerous endogenous and exogenous signals from both apic...

  • Article
  • Open Access
12 Citations
6,914 Views
12 Pages

Real-Time PCR Protocol for Detection and Quantification of Three Pathogenic Members of the Vibrionaceae Family

  • Cátia Costa,
  • Guilherme D. Ferreira,
  • Marco Simões,
  • Joana L. Silva and
  • Maria J. Campos

Vibriosis, an often-fatal disease induced by pathogenic members of the Vibrionaceae family, causes severe economic losses in aquacultures. To mitigate/avoid vibriosis outbursts, it is vital to detect and quantify these pathogens as early as possible....

  • Article
  • Open Access
9 Citations
2,691 Views
13 Pages

Responses of Bacterial Community Structure, Diversity, and Chemical Properties in the Rhizosphere Soil on Fruiting-Body Formation of Suillus luteus

  • Yixin Zhou,
  • Zhichao Shi,
  • Qiliang Pang,
  • Xiufeng Liang,
  • Hongtao Li,
  • Xin Sui,
  • Chongwei Li and
  • Fuqiang Song

Mycorrhiza helper bacteria (MHB) play an important role in driving mycorrhizal formation. There are few reports on the relationship between bacteria and fruiting growths. Taking mycorrhizal rhizosphere soil from sporocarps of the S. luteus and non-my...

  • Review
  • Open Access
78 Citations
12,592 Views
25 Pages

Lactic Acid Bacteria and Bacteriocins: Novel Biotechnological Approach for Biopreservation of Meat and Meat Products

  • Dipanwita Bhattacharya,
  • Pramod Kumar Nanda,
  • Mirian Pateiro,
  • José M. Lorenzo,
  • Pubali Dhar and
  • Arun K. Das

Meat and meat products are perishable in nature, and easily susceptible to microbial contamination and chemical deterioration. This not only results in an increased risk to health of consumers, but also causes economic loss to the meat industry. Some...

  • Article
  • Open Access
12 Citations
4,681 Views
17 Pages

Polyhydroxyalkanoate (PHA) Biopolymer Synthesis by Marine Bacteria of the Malaysian Coral Triangle Region and Mining for PHA Synthase Genes

  • Athraa Alsaadi,
  • Sree Selva Kumar Ganesen,
  • Tan Suet May Amelia,
  • Radwa Moanis,
  • Eveline Peeters,
  • Sevakumaran Vigneswari and
  • Kesaven Bhubalan

Polyhydroxyalkanoate (PHA), a biodegradable and plastic-like biopolymer, has been receiving research and industrial attention due to severe plastic pollution, resource depletion, and global waste issues. This has spurred the isolation and characteris...

  • Article
  • Open Access
11 Citations
4,078 Views
19 Pages

Screening of Bacteria Inhibiting Clostridium perfringens and Assessment of Their Beneficial Effects In Vitro and In Vivo with Whole Genome Sequencing Analysis

  • Zipeng Jiang,
  • Weifa Su,
  • Mingzhi Yang,
  • Wentao Li,
  • Tao Gong,
  • Yu Zhang,
  • Chaoyue Wen,
  • Xinxia Wang,
  • Yizhen Wang and
  • Zeqing Lu
  • + 1 author

Various countries and organizations call for banning the use of antibiotic growth promoters (AGPs) as prophylaxis and for growth promotion in the livestock industry. Hence, seeking a substitute for antibiotics is strongly required by the livestock in...

  • Article
  • Open Access
8 Citations
4,568 Views
15 Pages

Assessment of Indoor Air Quality of Four Primary Health Care Centers in Qatar

  • Hana Abdelrahman,
  • Lubna Abu-Rub,
  • Hassan Al Mana,
  • Yousef Alhorr,
  • Asmaa Al Thani,
  • Hamda Qotba,
  • Hadi M. Yassine and
  • Nahla O. Eltai

Airborne bacteria pose a potential risk to human health upon inhalation in the indoor environments of health care facilities. Airborne bacteria may originate from various sources, including patients, workers, and daily visitors. Hence, this study inv...

  • Article
  • Open Access
3 Citations
2,595 Views
13 Pages

Molecular Characterization and Antibiotic Susceptibility of Non-PCV13 Pneumococcal Serotypes among Vaccinated Children in Cape Coast, Ghana

  • Richael O. Mills,
  • Mohammed R. Abdullah,
  • Samuel A. Akwetey,
  • Dorcas C. Sappor,
  • Johan A. Bolivar,
  • Gustavo Gámez,
  • Mark P. G. van der Linden and
  • Sven Hammerschmidt

Preventive strategies involving the use of pneumococcal conjugate vaccines (PCVs) are known to drastically reduce pneumococcal disease. However, PCV vaccination has been plagued with serotype replacement by non-PCV serotypes. In this study, we descri...

  • Review
  • Open Access
20 Citations
5,846 Views
23 Pages

The Protective Effects of Nutraceutical Components in Methotrexate-Induced Toxicity Models—An Overview

  • Gheorghe-Eduard Marin,
  • Maria-Adriana Neag,
  • Codrin-Constantin Burlacu and
  • Anca-Dana Buzoianu

There are multiple concerns associated with methotrexate (MTX), widely recognized for anti-neoplastic and anti-inflammatory effects in life-threatening disease conditions, i.e., acute lymphoblastic leukemia, non-Hodgkin’s lymphoma, psoriasis, a...

  • Article
  • Open Access
1 Citations
3,561 Views
15 Pages

The increase in cyanobacterial blooms linked to climate change and the eutrophication of water bodies is a global concern. The harmful cyanobacterium Microcystis aeruginosa is one of the most common bloom-forming species whose removal from fresh wate...

  • Article
  • Open Access
3 Citations
2,744 Views
11 Pages

Electrochemical Enrichment and Isolation of Electrogenic Bacteria from 0.22 µm Filtrate

  • Sota Ihara,
  • Satoshi Wakai,
  • Tomoko Maehara and
  • Akihiro Okamoto

Ultramicrobacteria (UMB) that can pass through a 0.22 µm filter are attractive because of their novelty and diversity. However, isolating UMB has been difficult because of their symbiotic or parasitic lifestyles in the environment. Some UMB hav...

  • Article
  • Open Access
5 Citations
3,519 Views
19 Pages

Detection and Molecular Characterization of Rotavirus Infections in Children and Adults with Gastroenteritis from Vojvodina, Serbia

  • Aleksandra Patić,
  • Vladimir Vuković,
  • Gordana Kovačević,
  • Vladimir Petrović,
  • Mioljub Ristić,
  • Milan Djilas,
  • Petar Knežević,
  • Tatjana Pustahija,
  • Mirjana Štrbac and
  • Ivana Hrnjaković Cvjetković
  • + 2 authors

Rotaviruses (RV) are the leading cause of gastroenteritis in infants, young children, and adults, responsible for serious disease burden. In the period 2012–2018, a cross-sectional study was conducted using stool samples collected from patients...

  • Article
  • Open Access
3 Citations
1,945 Views
18 Pages

Naturally fermented black table olives are processed at low pH in the presence of high sodium chloride concentrations ranging from 8 to 12% (w v−1). Reducing the salt content of brine has become an urgent issue as it is responsible for several...

  • Review
  • Open Access
115 Citations
15,875 Views
25 Pages

Gut Microbiota-Derived Short-Chain Fatty Acids: Impact on Cancer Treatment Response and Toxicities

  • Ghanyah H. Al-Qadami,
  • Kate R. Secombe,
  • Courtney B. Subramaniam,
  • Hannah R. Wardill and
  • Joanne M. Bowen

The gut microbiota has emerged as a key modulator of cancer treatment responses in terms of both efficacy and toxicity. This effect is clearly mediated by processes impacting the activation and modulation of immune responses. More recently, the abili...

  • Article
  • Open Access
51 Citations
6,524 Views
22 Pages

A Plant Endophytic Bacterium Priestia megaterium StrainBP-R2 Isolated from the Halophyte Bolboschoenus planiculmis Enhances Plant Growth under Salt and Drought Stresses

  • Hau-Hsuan Hwang,
  • Pei-Ru Chien,
  • Fan-Chen Huang,
  • Pin-Hsien Yeh,
  • Shih-Hsun Walter Hung,
  • Wen-Ling Deng and
  • Chieh-Chen Huang

Global warming and climate change have contributed to the rise of weather extremes. Severe drought and soil salinization increase because of rising temperatures. Economically important crop production and plant growth and development are hindered whe...

  • Article
  • Open Access
31 Citations
3,796 Views
19 Pages

This study aimed to investigate the protective effect of a novel exopolysaccharide EPSRam12, produced by Lacticaseibacillus rhamnosus Ram12, against D-galactose-induced brain injury and gut microbiota dysbiosis in mice. The findings demonstrate that...

  • Article
  • Open Access
6 Citations
2,427 Views
13 Pages

Evaluation of Drug-Induced Liver Injury in Hospitalized Patients with SARS-CoV-2 Infection

  • Nicoleta Mihai,
  • Catalin Tiliscan,
  • Constanta Angelica Visan,
  • Laurentiu Stratan,
  • Oana Ganea,
  • Stefan Sorin Arama,
  • Mihai Lazar and
  • Victoria Arama

Elevated liver enzymes are frequently reported in SARS-CoV-2-infected patients. Several mechanisms of liver injury have been proposed, but no clear conclusions were drawn. We aimed to evaluate hepatocellular and cholestatic injury in relation to the...

  • Article
  • Open Access
6 Citations
2,894 Views
18 Pages

The intensive and extensive broiler production systems imply different veterinary interventions, including the use of antimicrobials. This study aimed to compare the antimicrobial susceptibility profiles of Escherichia coli isolated from both systems...

  • Article
  • Open Access
11 Citations
2,792 Views
19 Pages

Hypervirulence and Multiresistance to Antibiotics in Klebsiella pneumoniae Strains Isolated from Patients with Hospital- and Community-Acquired Infections in a Mexican Medical Center

  • Areli Bautista-Cerón,
  • Eric Monroy-Pérez,
  • Luis Rey García-Cortés,
  • Ernesto Arturo Rojas-Jiménez,
  • Felipe Vaca-Paniagua and
  • Gloria Luz Paniagua-Contreras

Klebsiella pneumoniae is a pathogenic bacterium associated with different infectious diseases. This study aimed to establish the different association profiles of virulence genes related to the hypermucoviscous phenotype (HM), capsular serotypes, bio...

  • Article
  • Open Access
16 Citations
4,319 Views
15 Pages

Streptococcus salivarius 24SMBc Genome Analysis Reveals New Biosynthetic Gene Clusters Involved in Antimicrobial Effects on Streptococcus pneumoniae and Streptococcus pyogenes

  • Gaia Vertillo Aluisio,
  • Ambra Spitale,
  • Luca Bonifacio,
  • Grete Francesca Privitera,
  • Aldo Stivala,
  • Stefania Stefani and
  • Maria Santagati

Streptococcus salivarius 24SMBc is an oral probiotic with antimicrobial activity against the otopathogens Streptococcus pyogenes and Streptococcus pneumoniae. Clinical studies have reinforced its role in reducing the recurrence of upper respiratory t...

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Microorganisms - ISSN 2076-2607