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Journal of Personalized Medicine, Volume 15, Issue 1

January 2025 - 39 articles

Cover Story: B3 breast lesions, or "lesions of uncertain malignant potential", represent a challenging area in breast pathology. Detected during routine breast imaging and biopsy, these lesions include atypical ductal hyperplasia, lobular neoplasia, flat epithelial atypia, and papillary lesions, among others. While not outright malignant, B3 lesions carry an elevated risk of developing into breast cancer or being associated with malignancy. Accurate diagnosis and management are critical, requiring a multidisciplinary approach to balance overtreatment risks against ensuring patient safety. This paper explores the pathology, diagnostic challenges, and evolving management strategies for B3 lesions. View this paper
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Articles (39)

  • Study Protocol
  • Open Access
2 Citations
3,334 Views
21 Pages

A Protocol for AI-Powered Tools to Enhance Mobility and Function in Older Adults: An Evidence and Gap Map

  • Mirella Veras,
  • Jordi Pardo,
  • Mê-Linh Lê,
  • Cindy Jussup,
  • José Carlos Tatmatsu-Rocha and
  • Vivian Welch

14 January 2025

Introduction: Artificial intelligence (AI) is transforming healthcare by enhancing diagnostic accuracy, treatment, and patient monitoring, benefiting older adults by offering personalized care plans. AI-powered tools help manage chronic conditions an...

  • Article
  • Open Access
19 Citations
4,831 Views
25 Pages

A Novel CNN-Based Framework for Alzheimer’s Disease Detection Using EEG Spectrogram Representations

  • Konstantinos Stefanou,
  • Katerina D. Tzimourta,
  • Christos Bellos,
  • Georgios Stergios,
  • Konstantinos Markoglou,
  • Emmanouil Gionanidis,
  • Markos G. Tsipouras,
  • Nikolaos Giannakeas,
  • Alexandros T. Tzallas and
  • Andreas Miltiadous

14 January 2025

Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that poses critical challenges in global healthcare due to its increasing prevalence and severity. Diagnosing AD and other dementias, such as frontotemporal dement...

  • Review
  • Open Access
1 Citations
3,869 Views
20 Pages

13 January 2025

Sensory evoked potentials (EPs), namely, somatosensory, visual, and brainstem acoustic EPs, are used in neurosurgery to monitor the corresponding functions with the aim of preventing iatrogenic neurological complications. Functional deficiency usuall...

  • Article
  • Open Access
1,505 Views
18 Pages

Health Professionals’ Preferences for Next-Generation Sequencing in the Diagnosis of Suspected Genetic Disorders in the Paediatric Population

  • Mario Cesare Nurchis,
  • Gerardo Altamura,
  • Gian Marco Raspolini,
  • Enrico Capobianco,
  • Luca Salmasi and
  • Gianfranco Damiani

10 January 2025

Background/Objectives: Next-generation sequencing (NGS) can explain how genetics influence morbidity and mortality in children. However, it is unclear whether health providers will perceive and use such treatments. We conducted a discrete choice expe...

  • Article
  • Open Access
1,276 Views
11 Pages

Assessing the TNM Classification for Periprosthetic Joint Infections of the Knee: Predictive Validity for Functional and Subjective Outcomes

  • Arne Kienzle,
  • Sandy Walter,
  • Paul Köhli,
  • Clemens Gwinner,
  • Sebastian Hardt,
  • Michael Müller,
  • Carsten Perka and
  • Stefanie Donner

10 January 2025

Background: Periprosthetic joint infection (PJI) following knee arthroplasty can significantly compromise patient mobility and quality of life. The newly proposed TNM classification system, adapted from oncology, categorizes PJI severity but has not...

  • Article
  • Open Access
4 Citations
2,377 Views
13 Pages

Prostatic Artery Embolization in Elderly Comorbid Patients with Benign Prostatic Hyperplasia: Safety, Efficacy, and Predictive Factors of Clinical Failure

  • Federico Zorzi,
  • Giulio Rossin,
  • Michelangelo Digregorio,
  • Simone Lavecchia,
  • Andrea Piasentin,
  • Fabio Traunero,
  • Carmelo Morreale,
  • Michele Rizzo,
  • Tommaso Cai and
  • Carlo Trombetta
  • + 2 authors

10 January 2025

Background: This study aims to evaluate the safety and efficacy of prostatic artery embolization (PAE) in elderly, multimorbid patients with benign prostatic hyperplasia (BPH). Additionally, it seeks to identify technical and clinical factors that pr...

  • Article
  • Open Access
3 Citations
2,333 Views
15 Pages

A Mediation Appraisal of Neuropathic-like Symptoms, Pain Catastrophizing, and Central Sensitization-Related Signs in Adults with Knee Osteoarthritis—A Cross-Sectional Study

  • Fausto Salaffi,
  • Marina Carotti,
  • Sonia Farah,
  • Carlo Ciccullo,
  • Antonio Pompilio Gigante,
  • Francesca Bandinelli and
  • Marco Di Carlo

10 January 2025

Objective. To investigate the relationships among neuropathic pain (NP), pain catastrophizing (PC), and central sensitization (CS) in relation to functional status and radiological damage in patients with knee osteoarthritis (OA). Methods. This cross...

  • Review
  • Open Access
13 Citations
5,211 Views
21 Pages

The Role of Artificial Intelligence and Emerging Technologies in Advancing Total Hip Arthroplasty

  • Luca Andriollo,
  • Aurelio Picchi,
  • Giulio Iademarco,
  • Andrea Fidanza,
  • Loris Perticarini,
  • Stefano Marco Paolo Rossi,
  • Giandomenico Logroscino and
  • Francesco Benazzo

9 January 2025

Total hip arthroplasty (THA) is a widely performed surgical procedure that has evolved significantly due to advancements in artificial intelligence (AI) and robotics. As demand for THA grows, reliable tools are essential to enhance diagnosis, preoper...

  • Article
  • Open Access
1 Citations
1,653 Views
15 Pages

6 January 2025

Purpose: Augmented reality (AR) may allow vitreoretinal surgeons to leverage microscope-integrated digital imaging systems to analyze and highlight key retinal anatomic features in real time, possibly improving safety and precision during surgery. By...

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J. Pers. Med. - ISSN 2075-4426