You are currently viewing a new version of our website. To view the old version click .

Diagnostics, Volume 13, Issue 16

August-2 2023 - 104 articles

Cover Story: In medical mycology, the diagnosis of invasive pulmonary aspergillosis (IPA) in intensive care unit (ICU) patients is crucial, since most clinical signs are not specific for invasive fungal infections. For microbiological diagnostics, different methods are available. In addition to the conventional culture-based approaches like staining and culture, non-culture-based methods can increase test sensitivity and improve the time-to-result. In this review, we evaluate and discuss the value of non-culture-based methods (galactomannan, (1→3)-β-D-glucan, Aspergillus PCR, new biomarker/targets) for diagnosing IPA in ICU patients. The combination of non-culture-based methods and the investigation of different respiratory specimens seem to be the best diagnostic pathway to detect IPA in ICU patients. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (104)

  • Article
  • Open Access
5 Citations
3,723 Views
11 Pages

21 August 2023

(1) Background: This study aimed to evaluate the accuracy of predicting the histology of diminutive colonic polyps (DCPs) (≤5 mm) using i-scan optical enhancement (OE) based on the narrow-band imaging international colorectal endoscopic (NICE) cla...

  • Review
  • Open Access
6 Citations
4,939 Views
42 Pages

Rare Solid Pancreatic Lesions on Cross-Sectional Imaging

  • Ana Veron Sanchez,
  • Nuria Santamaria Guinea,
  • Silvia Cayon Somacarrera,
  • Ilias Bennouna,
  • Martina Pezzullo and
  • Maria Antonietta Bali

21 August 2023

Several solid lesions can be found within the pancreas mainly arising from the exocrine and endocrine pancreatic tissue. Among all pancreatic malignancies, the most common subtype is pancreatic ductal adenocarcinoma (PDAC), to a point that pancreatic...

  • Review
  • Open Access
6 Citations
2,428 Views
11 Pages

Microbiological Non-Culture-Based Methods for Diagnosing Invasive Pulmonary Aspergillosis in ICU Patients

  • Ulrike Scharmann,
  • Hedda Luise Verhasselt,
  • Lisa Kirchhoff,
  • Dan-Tiberiu Furnica,
  • Joerg Steinmann and
  • Peter-Michael Rath

21 August 2023

The diagnosis of invasive pulmonary aspergillosis (IPA) in intensive care unit (ICU) patients is crucial since most clinical signs are not specific to invasive fungal infections. To detect an IPA, different criteria should be considered. Next to host...

  • Article
  • Open Access
5 Citations
1,973 Views
12 Pages

Investigation of the Role of BMP2 and -4 in ASD, VSD and Complex Congenital Heart Disease

  • Dimitrios Bobos,
  • Giannoula Soufla,
  • Dimitrios C. Angouras,
  • Ioannis Lekakis,
  • Sotirios Georgopoulos and
  • Euthemia Melissari

21 August 2023

Congenital heart malformations (CHMs) make up between 2 and 3% of annual human births. Bone morphogenetic proteins (BMPs) signalling is required for chamber myocardium development. We examined for possible molecular defects in the bone morphogenetic...

  • Systematic Review
  • Open Access
19 Citations
7,521 Views
29 Pages

Keratoconus Diagnosis: From Fundamentals to Artificial Intelligence: A Systematic Narrative Review

  • Sana Niazi,
  • Marta Jiménez-García,
  • Oliver Findl,
  • Zisis Gatzioufas,
  • Farideh Doroodgar,
  • Mohammad Hasan Shahriari and
  • Mohammad Ali Javadi

21 August 2023

The remarkable recent advances in managing keratoconus, the most common corneal ectasia, encouraged researchers to conduct further studies on the disease. Despite the abundance of information about keratoconus, debates persist regarding the detection...

  • Article
  • Open Access
8 Citations
2,718 Views
11 Pages

Assessment and Monitoring of Nail Psoriasis with Ultra-High Frequency Ultrasound: Preliminary Results

  • Alessandra Michelucci,
  • Valentina Dini,
  • Giorgia Salvia,
  • Giammarco Granieri,
  • Flavia Manzo Margiotta,
  • Salvatore Panduri,
  • Riccardo Morganti and
  • Marco Romanelli

21 August 2023

Psoriatic onychopathy is one of the clinical presentations of psoriasis and a well-known risk factor for the development of psoriatic arthritis. High-frequency ultrasounds (HFUS > 20 MHz) have recently been used to evaluate the nail apparatus of h...

  • Article
  • Open Access
7 Citations
2,342 Views
20 Pages

21 August 2023

Velopharyngeal insufficiency (VPI) is a type of pharyngeal function dysfunction that causes speech impairment and swallowing disorder. Speech therapists play a key role on the diagnosis and treatment of speech disorders. However, there is a worldwide...

  • Article
  • Open Access
12 Citations
3,224 Views
17 Pages

Prediction of Pubertal Mandibular Growth in Males with Class II Malocclusion by Utilizing Machine Learning

  • Grant Zakhar,
  • Samir Hazime,
  • George Eckert,
  • Ariel Wong,
  • Sarkhan Badirli and
  • Hakan Turkkahraman

21 August 2023

The goal of this study was to create a novel machine learning (ML) model that can predict the magnitude and direction of pubertal mandibular growth in males with Class II malocclusion. Lateral cephalometric radiographs of 123 males at three time poin...

  • Article
  • Open Access
6 Citations
2,285 Views
15 Pages

Identification of Intestinal Microbial Community in Gallstone Patients with Metagenomic Next-Generation Sequencing

  • Li Ding,
  • Su Wang,
  • Wenrong Jiang,
  • Yingxin Miao,
  • Wenjian Liu,
  • Feng Yang,
  • Jinghao Zhang,
  • Wenjing Chi,
  • Tao Liu and
  • Yue Liu
  • + 3 authors

21 August 2023

Gallstone disease (GD) is one of the most common gastrointestinal diseases worldwide. Nowadays, intestinal microbiota are thought to play important roles in the formation of gallstones. In our study, human fecal samples were extracted for metagenomic...

  • Communication
  • Open Access
4 Citations
4,642 Views
7 Pages

20 August 2023

Progressive Supranuclear Palsy and Multiple-System Atrophy are entities within the spectrum of atypical parkinsonism. The role of imaging methods in the diagnosis and differentiation between PSP and MSA is limited and Magnetic Resonance Imaging (MRI)...

of 11

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Diagnostics - ISSN 2075-4418