Next Article in Journal
Deep and Densely Connected Networks for Classification of Diabetic Retinopathy
Next Article in Special Issue
The Expansion of Cholangioscopy: Established and Investigational Uses of SpyGlass in Biliary and Pancreatic Disorders
Previous Article in Journal
Sensor-as-a-Service: Convergence of Sensor Analytic Point Solutions (SNAPS) and Pay-A-Penny-Per-Use (PAPPU) Paradigm as a Catalyst for Democratization of Healthcare in Underserved Communities
Previous Article in Special Issue
A Pancreatic Inflammatory Myofibroblastic Tumor with Spontaneous Remission: A Case Report with a Literature Review
Open AccessArticle

Utility of Contrast-Enhanced Harmonic Endoscopic Ultrasonography for Early Diagnosis of Small Pancreatic Cancer

1
Second Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, Japan
2
Clinical Study Support Center, Wakayama Medical University Hospital, Wakayama 641-8509, Japan
3
Department of Radiology, Wakayama Minami Radiology Clinic, Wakayama 641-0012, Japan
4
Department of Radiology, Wakayama Medical University, Wakayama 641-8509, Japan
5
Second Department of Surgery, Wakayama Medical University, Wakayama 641-8509, Japan
*
Author to whom correspondence should be addressed.
Diagnostics 2020, 10(1), 23; https://doi.org/10.3390/diagnostics10010023
Received: 29 November 2019 / Revised: 26 December 2019 / Accepted: 30 December 2019 / Published: 1 January 2020
(This article belongs to the Special Issue Endoscopic Diagnostics for Pancreatobiliary Disorders)
This study aimed to assess whether contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS), compared to multidetector-row computed tomography (MDCT) and magnetic resonance imaging (MRI), is useful for early diagnosis of small pancreatic cancer (PC). Between March 2010 and June 2018, all three imaging modalities and surgery were performed for patients with a pancreatic solid lesion measuring ≤20 mm; diagnostic ability was compared among modalities. Fifty-one of 60 patients were diagnosed with PC (PC size in 41 patients: 11–20 mm; 10 patients: ≤10 mm). The sensitivity, specificity, and accuracy of CH-EUS, MDCT, and MRI for PC (11–20 mm) detection were 95%/83%/94%, 78%/83%/79%, and 73%/33%/68%, respectively. The diagnostic ability of CH-EUS was significantly superior compared with MDCT and MRI (p = 0.002 and p = 0.007, respectively). The sensitivity, specificity, and accuracy of CH-EUS, MDCT, and MRI for PC (≤10 mm) detection were 70%/100%/77%, 20%/100%/38%, and 50%/100%/62%, respectively. The diagnostic ability of CH-EUS tended to be superior to that of MDCT (p = 0.025). The sensitivity of MDCT for PC (≤10 mm) detection was significantly lower than that for PC (11–20 mm) detection (20% vs. 78%; p = 0.001). CH-EUS, compared to MDCT and MRI, is useful for diagnosing small PCs. View Full-Text
Keywords: early diagnosis of pancreatic cancer; contrast-enhanced harmonic endoscopic ultrasonography; magnetic resonance imaging; multidetector computed tomography early diagnosis of pancreatic cancer; contrast-enhanced harmonic endoscopic ultrasonography; magnetic resonance imaging; multidetector computed tomography
Show Figures

Figure 1

MDPI and ACS Style

Yamashita, Y.; Tanioka, K.; Kawaji, Y.; Tamura, T.; Nuta, J.; Hatamaru, K.; Itonaga, M.; Yoshida, T.; Ida, Y.; Maekita, T.; Iguchi, M.; Terada, M.; Sonomura, T.; Hirono, S.; Okada, K.-I.; Kawai, M.; Yamaue, H.; Kitano, M. Utility of Contrast-Enhanced Harmonic Endoscopic Ultrasonography for Early Diagnosis of Small Pancreatic Cancer. Diagnostics 2020, 10, 23.

AMA Style

Yamashita Y, Tanioka K, Kawaji Y, Tamura T, Nuta J, Hatamaru K, Itonaga M, Yoshida T, Ida Y, Maekita T, Iguchi M, Terada M, Sonomura T, Hirono S, Okada K-I, Kawai M, Yamaue H, Kitano M. Utility of Contrast-Enhanced Harmonic Endoscopic Ultrasonography for Early Diagnosis of Small Pancreatic Cancer. Diagnostics. 2020; 10(1):23.

Chicago/Turabian Style

Yamashita, Yasunobu; Tanioka, Kensuke; Kawaji, Yuki; Tamura, Takashi; Nuta, Junya; Hatamaru, Keiichi; Itonaga, Masahiro; Yoshida, Takeichi; Ida, Yoshiyuki; Maekita, Takao; Iguchi, Mikitaka; Terada, Masaki; Sonomura, Tetsuo; Hirono, Seiko; Okada, Ken-Ichi; Kawai, Manabu; Yamaue, Hiroki; Kitano, Masayuki. 2020. "Utility of Contrast-Enhanced Harmonic Endoscopic Ultrasonography for Early Diagnosis of Small Pancreatic Cancer" Diagnostics 10, no. 1: 23.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop