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Life, Volume 15, Issue 2

February 2025 - 192 articles

Cover Story: This review assesses global longitudinal strain (GLS) and left atrial strain (LAS) as echocardiographic biomarkers for diagnosing and characterizing HFpEF. Strain imaging, particularly speckle tracking echocardiography, offers a refined assessment of myocardial deformation, providing detailed insights into left heart function beyond traditional measures. Normal ranges for GLS and LAS are discussed, acknowledging demographic and technical influences. Clinical studies confirm the prognostic value of GLS and LAS in HFpEF, especially for predicting cardiovascular outcomes and distinguishing HFpEF from other dyspnea causes. Integration of these biomarkers into standard diagnostic practice requires an organized approach, and future guidelines should recommend their combined use for comprehensive HFpEF assessment. View this paper
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Articles (192)

  • Article
  • Open Access
1,857 Views
16 Pages

Quality of Life of Donors After Living Kidney Transplantation: A Cross-Sectional Study

  • Chrysanthi Skalioti,
  • Maria Smyrli,
  • Chrysoula Beletsioti,
  • Stathis Tsiakas,
  • Kalliopi Vallianou,
  • John N. Boletis and
  • Smaragdi Marinaki

19 February 2025

Living kidney transplantation yields better outcomes for recipients than deceased donation, though it may present long-term challenges for donors. This study assessed the quality of life (QoL) of living kidney donors in Greece using the SF-36 questio...

  • Article
  • Open Access
1,154 Views
14 Pages

Analysis of Biomarker Levels in Nasopharyngeal Swabs, Serum, and Saliva Across Different Health Conditions

  • Mina Pencheva,
  • Neshka Manchorova-Veleva,
  • David Baruh,
  • Georgi Rusinov and
  • Lyubomir Vangelov

19 February 2025

Background: Coronavirus disease 2019 (COVID-19) is associated with a wide variety of clinical manifestations. Aim: This study aims to evaluate the levels of angiotensin-converting enzyme 2 (ACE2), metalloprotease 17 (ADAM17), Interleukin-17A (IL-17A)...

  • Article
  • Open Access
2 Citations
1,176 Views
17 Pages

Habitat Suitability Assessment of Key Wildlife in Hainan Tropical Rainforest Based on ESDM

  • Wutao Yao,
  • Jin Yang,
  • Yong Ma,
  • Lixi Liu,
  • Erping Shang and
  • Shuyan Zhang

19 February 2025

Hainan tropical rainforest is the largest contiguous tropical rainforest in China, but it has experienced increasing disturbances from anthropogenic activities in recent decades due to economic and social development. However, the current status of w...

  • Article
  • Open Access
1 Citations
803 Views
16 Pages

19 February 2025

We examined long-term trends in the yellow-necked mouse (Apodemus flavicollis) in Lithuania using data collected from 1980 to 2024. Over 10,000 individuals were captured and 5666 were necropsied to measure standard morphometric traits, including body...

  • Article
  • Open Access
1,487 Views
12 Pages

Association Between Nephrolith Size and Location and Grade of Hydronephrosis

  • Sultan Abdulwadoud Alshoabi,
  • Abdulkhaleq Ayedh Binnuhaid,
  • Abdullatif Mothanna Almohtadi,
  • Halah Fuad Muslem,
  • Abdullgabbar M. Hamid,
  • Fahad H. Alhazmi,
  • Abdulaziz A. Qurashi,
  • Walaa M. Alsharif,
  • Awadia Gareeballah and
  • Amel F. Alzain
  • + 3 authors

19 February 2025

This research investigated the unstudied impact, in 416 cases of stone-induced hydronephrosis detected radiographically in 369 patients, of stone size on the stone’s location in the urinary tract and on the hydronephrosis grade. Most (62.5%) of...

  • Study Protocol
  • Open Access
1 Citations
1,559 Views
18 Pages

Clinical Validation of a Machine Learning-Based Biomarker Signature to Predict Response to Cytotoxic Chemotherapy Alone or Combined with Targeted Therapy in Metastatic Colorectal Cancer Patients: A Study Protocol and Review

  • Duilio Pagano,
  • Vincenza Barresi,
  • Alessandro Tropea,
  • Antonio Galvano,
  • Viviana Bazan,
  • Adele Caldarella,
  • Cristina Sani,
  • Gianpaolo Pompeo,
  • Valentina Russo and
  • Rosa Liotta
  • + 9 authors

19 February 2025

Metastatic colorectal cancer (mCRC) is a severe condition with high rates of illness and death. Current treatments are limited and not always effective because the cancer responds differently to drugs in different patients. This research aims to use...

  • Article
  • Open Access
952 Views
17 Pages

19 February 2025

The genus Camphora encompasses species of significant ecological and economic importance, such as C. parthenoxylon and C. officinarum, which exhibit distinct phenotypic traits and stress responses. This study seeks to elucidate the molecular basis of...

  • Article
  • Open Access
1,551 Views
13 Pages

Lower-Extremity Muscle Strength Symmetry Assessment Through Isokinetic Dynamometry

  • Yuanyuan Ren,
  • Sheng Zhou,
  • Guangzhen Cheng,
  • Yueqin Tang,
  • Guangge Wang and
  • Aming Lu

19 February 2025

Objective: This study aimed to establish a dominant and non-dominant limb muscle strength evaluation model to evaluate the asymmetry of lower extremity muscle strength. Methods: The hip, knee, ankle flexors and extensors of 86 runners were evaluated...

  • Review
  • Open Access
5 Citations
4,778 Views
29 Pages

Spent Mushroom Substrate-Derived Biochar and Its Applications in Modern Agricultural Systems: An Extensive Overview

  • Worawoot Aiduang,
  • Kritsana Jatuwong,
  • Tanongkiat Kiatsiriroat,
  • Wassana Kamopas,
  • Pimsiri Tiyayon,
  • Rotsukon Jawana,
  • Orlavanh Xayyavong and
  • Saisamorn Lumyong

18 February 2025

Spent mushroom substrate (SMS), a nutrient-dense byproduct of mushroom cultivation, has emerged as a promising feedstock for biochar production, offering a sustainable solution to modern agricultural and environmental challenges. This review explores...

  • Review
  • Open Access
2 Citations
9,509 Views
16 Pages

Anatomical-Based Diagnosis and Filler Injection Techniques: Lips and Philtrum

  • Gi-Woong Hong,
  • Wonseok Choi,
  • Song-Eun Yoon,
  • Jovian Wan and
  • Kyu-Ho Yi

18 February 2025

Lip augmentation has become increasingly popular in aesthetic medicine, driven by advancements in dermal filler technologies and injection techniques. This review provides a comprehensive overview of lip anatomy, age-related changes, and current best...

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Life - ISSN 2075-1729Creative Common CC BY license