Clinical Trials

Dear Colleagues,

This Topical Collection covers all aspects of the performance and findings of randomized controlled trials in human health. We publish articles on general trial methodology, research into trial processes, study protocols, statistical analysis plans for randomized controlled trials and traditional result papers, regardless of the outcome or significance of the findings. We also welcome systematic reviews of randomized controlled clinical trials.

Our goal is to promote transparency in reporting randomized trials and build an evidence base to inform the design and reporting of future trials. We consider articles or study protocols assessing aspects of the design, conduct or reporting of trials, as well as assessment and evaluation of lessons learned from past trials, including those that were prematurely ended. We advocate for the collective success of trials and the importance of linking publications together.

To facilitate the complete and transparent reporting of research, this Collection does not impose strict word upper limits. We request that the authors provide the details required to make the research replicable. Authors are asked to communicate not only all outcome measures, varying analyses and interpretations, but also in-depth descriptions of what they did and what they learned. This sharing of direct experience is fundamental to improving the quality and conduct of trials worldwide.

Prof. Dr. Pabulo H. Rampelotto
Dr. Anca Oana Docea
Prof. Dr. Katalin Prokai-Tatrai
Collection Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.