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Genes, Volume 9, Issue 3

March 2018 - 55 articles

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Cover Story: When Egyptologists at the Museum of Fine Arts, Boston, could not figure out the sex of a mummified head from an important 4000-year-old Egyptian tomb, they turned to the medical and scientific communities for help. In 2009, scientists extracted a molar in the hope of recovering sufficient uncontaminated DNA to provide the answer. Their first attempt failed because the DNA proved too degraded to yield results with the routinely employed DNA typing methodologies of the time. The FBI stepped in and applied the cutting-edge techniques described in this article to find the long-sought answer. View the paper here.

Articles (55)

  • Article
  • Open Access
19 Citations
4,535 Views
13 Pages

Yak IGF2 Promotes Fibroblast Proliferation Via Suppression of IGF1R and PI3KCG Expression

  • Quanwei Zhang,
  • Qi Wang,
  • Jishang Gong,
  • Jiaxing Du,
  • Yong Zhang and
  • Xingxu Zhao

20 March 2018

Insulin-like growth factor 2 (IGF2) recapitulates many of the activities of insulin and promotes differentiation of myoblasts and osteoblasts, which likely contribute to genetic variations of growth potential. However, little is known about the funct...

  • Article
  • Open Access
65 Citations
7,662 Views
22 Pages

Long Non-Coding RNAs Responsive to Salt and Boron Stress in the Hyper-Arid Lluteño Maize from Atacama Desert

  • Wilson Huanca-Mamani,
  • Raúl Arias-Carrasco,
  • Steffany Cárdenas-Ninasivincha,
  • Marcelo Rojas-Herrera,
  • Gonzalo Sepúlveda-Hermosilla,
  • José Carlos Caris-Maldonado,
  • Elizabeth Bastías and
  • Vinicius Maracaja-Coutinho

20 March 2018

Long non-coding RNAs (lncRNAs) have been defined as transcripts longer than 200 nucleotides, which lack significant protein coding potential and possess critical roles in diverse cellular processes. Long non-coding RNAs have recently been functionall...

  • Article
  • Open Access
65 Citations
6,964 Views
16 Pages

Genomic Characterization of Listeria monocytogenes Isolates Associated with Clinical Listeriosis and the Food Production Environment in Ireland

  • Amber Hilliard,
  • Dara Leong,
  • Amy O’Callaghan,
  • Eamonn P. Culligan,
  • Ciara A. Morgan,
  • Niall DeLappe,
  • Colin Hill,
  • Kieran Jordan,
  • Martin Cormican and
  • Cormac G.M. Gahan

20 March 2018

Listeria monocytogenes is a major human foodborne pathogen that is prevalent in the natural environment and has a high case fatality rate. Whole genome sequencing (WGS) analysis has emerged as a valuable methodology for the classification of L. monoc...

  • Article
  • Open Access
14 Citations
7,224 Views
17 Pages

Comparative Analysis of Surface Layer Glycoproteins and Genes Involved in Protein Glycosylation in the Genus Haloferax

  • Yarden Shalev,
  • Shannon M. Soucy,
  • R. Thane Papke,
  • J. Peter Gogarten,
  • Jerry Eichler and
  • Uri Gophna

20 March 2018

Within the Haloferax genus, both the surface (S)-layer protein, and the glycans that can decorate it, vary between species, which can potentially result in many different surface types, analogous to bacterial serotypes. This variation may mediate phe...

  • Review
  • Open Access
47 Citations
11,394 Views
20 Pages

Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction

  • Corina T. Madreiter-Sokolowski,
  • Armin A. Sokolowski,
  • Markus Waldeck-Weiermair,
  • Roland Malli and
  • Wolfgang F. Graier

16 March 2018

Senescence is related to the loss of cellular homeostasis and functions, which leads to a progressive decline in physiological ability and to aging-associated diseases. Since mitochondria are essential to energy supply, cell differentiation, cell cyc...

  • Article
  • Open Access
17 Citations
5,665 Views
10 Pages

16 March 2018

The evolution of intrinsic barriers to gene flow is a crucial step in the process of speciation. Chromosomal changes caused by fusion and fission events are one such barrier and are common in several groups of Lepidoptera. However, it remains unclear...

  • Review
  • Open Access
125 Citations
27,634 Views
19 Pages

Dietary Alteration of the Gut Microbiome and Its Impact on Weight and Fat Mass: A Systematic Review and Meta-Analysis

  • George Kunnackal John,
  • Lin Wang,
  • Julie Nanavati,
  • Claire Twose,
  • Rajdeep Singh and
  • Gerard Mullin

16 March 2018

Dietary alteration of the gut microbiome is an important target in the treatment of obesity. Animal and human studies have shown bidirectional weight modulation based on the probiotic formulation used. In this study, we systematically reviewed the li...

  • Article
  • Open Access
51 Citations
7,304 Views
16 Pages

16 March 2018

Cytokinin oxidase/dehydrogenases (CKXs) play a critical role in the irreversible degradation of cytokinins, thereby regulating plant growth and development. Brassica napus is one of the most widely cultivated oilseed crops worldwide. With the complet...

  • Review
  • Open Access
69 Citations
11,485 Views
25 Pages

Phylogeny and Phylogeography of Rhizobial Symbionts Nodulating Legumes of the Tribe Genisteae

  • Tomasz Stępkowski,
  • Joanna Banasiewicz,
  • Camille E. Granada,
  • Mitchell Andrews and
  • Luciane M. P. Passaglia

14 March 2018

The legume tribe Genisteae comprises 618, predominantly temperate species, showing an amphi-Atlantic distribution that was caused by several long-distance dispersal events. Seven out of the 16 authenticated rhizobial genera can nodulate particular Ge...

  • Article
  • Open Access
12 Citations
5,869 Views
18 Pages

Distinct Roles of Velvet Complex in the Development, Stress Tolerance, and Secondary Metabolism in Pestalotiopsis microspora, a Taxol Producer

  • Oren Akhberdi,
  • Qian Zhang,
  • Dan Wang,
  • Haichuan Wang,
  • Xiaoran Hao,
  • Yanjie Liu,
  • Dongsheng Wei and
  • Xudong Zhu

14 March 2018

The velvet family proteins have been shown to play critical roles in fungal secondary metabolism and development. However, variations of the roles have been observed in different fungi. We report here the observation on the role of three velvet compl...

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