is the causative agent of enteric redmouth disease, a bacterial infection of marine and freshwater fish. The disease mainly affects salmonids, and outbreaks have significant economic impact on fish farms all over the world. Vaccination routines are in place against the major serotypes of Y. ruckeri
but are not effective in all cases. Despite the economic importance of enteric redmouth disease, a detailed molecular understanding of the disease is lacking. A considerable number of mostly omics-based studies have been performed in recent years to identify genes related to Y. ruckeri
virulence. This review summarizes the knowledge on Y. ruckeri
virulence factors. Understanding the molecular pathogenicity of Y. ruckeri
will aid in developing more efficient vaccines and antimicrobial compounds directed against enteric redmouth disease.
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