Overcoming Fish Defences: The Virulence Factors of Yersinia ruckeri
1
Department of Biosciences, University of Oslo, 0316 Oslo, Norway
2
Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG1 4FQ, UK
*
Author to whom correspondence should be addressed.
Genes 2019, 10(9), 700; https://doi.org/10.3390/genes10090700
Received: 27 July 2019 / Revised: 2 September 2019 / Accepted: 5 September 2019 / Published: 11 September 2019
(This article belongs to the Special Issue Host-Bacterial Associations in Marine Organisms)
Yersinia ruckeri is the causative agent of enteric redmouth disease, a bacterial infection of marine and freshwater fish. The disease mainly affects salmonids, and outbreaks have significant economic impact on fish farms all over the world. Vaccination routines are in place against the major serotypes of Y. ruckeri but are not effective in all cases. Despite the economic importance of enteric redmouth disease, a detailed molecular understanding of the disease is lacking. A considerable number of mostly omics-based studies have been performed in recent years to identify genes related to Y. ruckeri virulence. This review summarizes the knowledge on Y. ruckeri virulence factors. Understanding the molecular pathogenicity of Y. ruckeri will aid in developing more efficient vaccines and antimicrobial compounds directed against enteric redmouth disease.
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Keywords:
aquaculture; plasmid; fish disease; Yersinia ruckeri; virulence factor
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MDPI and ACS Style
Wrobel, A.; Leo, J.C.; Linke, D. Overcoming Fish Defences: The Virulence Factors of Yersinia ruckeri. Genes 2019, 10, 700.
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