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Microfluidics-Nano-Integration for Synthesis and Sensing

Optical Microsystems Laboratory, Mechanical and Industrial Engineering Department, Concordia University, 1455 de Maisonneuve Blvd. W., Montréal, QC H3G 1M8, Canada
Author to whom correspondence should be addressed.
Polymers 2012, 4(2), 1278-1310;
Received: 29 May 2012 / Accepted: 13 June 2012 / Published: 20 June 2012
The recent progress and achievements in the development of preparation of nano and microparticles in a microfluidic environment is reviewed. Microfluidics exploit fluid mechanics to create particles with a narrow range of sizes and offers a finely controllable route to tune the shape and composition of nanomaterials. The advantages of both continuous flow- and droplet-based synthesis of polymers and nanoparticles, in comparison with the traditional stirred flasks methods are discussed in detail by using numerous recent examples from the literature as well as from the authors’ work. The controllability of the size distribution of the particles is discussed in terms of the fabrication approach and the characteristics of the microfluidic reactors. A special attention is paid to metal-polymer nanocomposites prepared through microfluidic routes and their application in bio-sensing. Directions for future development of microfluidic synthesis of high quality nanoparticles are discussed. View Full-Text
Keywords: polymer synthesis; microreactors; nanoparticles; sensing; nanocomposite materials polymer synthesis; microreactors; nanoparticles; sensing; nanocomposite materials
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Badilescu, S.; Packirisamy, M. Microfluidics-Nano-Integration for Synthesis and Sensing. Polymers 2012, 4, 1278-1310.

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